UbiCREST technology is exclusively licensed to Boston Biochem by the laboratory of Prof. David Komander
|What is UbiCREST?|
The UbiCREST (Ubiquitin Chain Restriction Analysis) Deubiquitinase Enzyme Set (Catalog # K-400) is designed to analyze the ubiquitin linkages present in free polyubiquitin chains or polyubiquitin chains conjugated to a substrate protein (linked Komander paper). Eight ubiquitin linkage-specific deubiquitinases (DUBs), along with DUB reaction buffer, are included in sufficient amounts to carry out 5 UbiCREST analysis experiments. This technology is exclusively licensed to Boston Biochem by the laboratory of Dr. David Komander (read what he has to say about UbiCREST and Boston Biochem below). Learn more about UbiCREST.
UbiCREST: Developed by Ubiquitin Researchers FOR Ubiquitin Researchers
UbiCREST was developed at the Komander Laboratory at the prestigious Medical Research Council Laboratory of Molecular Biology. "We desperately need new orthogonal methods to characterise atypical ubiquitin chain types," says David Komander, Ph.D., Group Leader at the MRC Laboratory of Molecular Biology. "I am convinced that UbiCREST can have a high impact in the field, especially in conjunction with complementary methods. It should allow new insights for the still poorly characterised atypical ubiquitin chain types."