Transcription Factors
Bish, R. A. and M. P. Myers (2007). "Werner Helicase-interacting Protein 1 Binds Poly-ubiquitin via Its Zinc Finger Domain." J. Biol. Chem. 282(32): 23184-23193.
Burnett, B.G., et al. (2009) "Regulation of SMN Protein Stability." Mol. Cell. Biol. 29(5): 1107-1115.
Chang, W., et al. (2003) "TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres." Genes & Dev. 17: 1328-1333.
Daulny, A., et al. (2008) "Modulation of RNA polymerase II subunit composition by ubiquitylation." PNAS 105(50): 19649-19654.
de Thonel, A., et al. (2010) “HSP27 controls GATA-1 protein level during erythroid cell differentiation.” Blood116: 85 - 96.
Frampton, J., et al. (2006) "Postreplication Repair and PCNA Modification in Schizosaccharomyces pombe." Mol. Biol. Cell 17(7): 2976-2985.
Guo, Y., et al. (2010) “Blockade of the Ubiquitin Protease UBP43 Destabilizes Transcription Factor PML/RAR and Inhibits the Growth of Acute Promyelocytic Leukemia.” Cancer Res. 70: 9875-9885.
Gurova K. V., et al. (2005) "Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors." PNAS 102(48): 17448-17453.
Gurtan, A. M., et al. (2006) "The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly." J. Biol. Chem. 281(16): 10896-10905.
Haracska, L., et al. (2006) "Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis." PNAS 103(17): 6477-6482.
Havens, C. G., et al. (2006) "Regulation of Late G1/S Phase Transition and APCCdh1 by Reactive Oxygen Species." Mol. Cell. Biol. 26(12): 4701-4711.
Hwang, X-S., et al. (2009) "Two proteolytic pathways regulate DNA repair by co-targeting the Mgt1 alkylguanine transferase." PNAS 106(7): 2142-2147.
Jones, J.M., et al. (2003) "Autoubiquitylation of the V(D)J recombinase protein RAG1." PNAS 100(26): 15446-15451.
Jung Y. and Lippard S.J. (2005) "RNA Polymerase II Blockage by Cisplatin-damaged DNA: Stability and poly-ubiquitylation of stalled polymerase." J. Biol. Chem.: 281-25001-25005.
Jung, Y. and S. J. Lippard (2006). "RNA Polymerase II Blockage by Cisplatin-damaged DNA: Stability and poly-ubiquitylation of stalled polymerase." J. Biol. Chem. 281(3): 1361-1370.
Kang, T.-H., et al. (2010) “Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein” Nucleic Acids Res. 10.1093/nar/gkq1318.*
Karagianni, P., et al. (2008) "ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation" Mol. Cell. Biol. 28: 705-17.
Kerns, S. L., et al. (2007). "Geminin Prevents Re-replication during Xenopus Development." J. Biol. Chem. 282(8): 5514-5521.
Kuznetsova, A.V., et al. (2003) "von Hippel-Lindau protein binds hyper-phosphorylated large subunit RNA polymerase II through a praline hydroxylation motif and targets it for ubiquitination." PNAS 100(5): 2706-2711.
Lagarou, A., et al. (2008) "KDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing." Genes & Dev. 22(20): 2799-2810.
Laine, A., I. et al. (2006). "Regulation of p53 Localization and Activity by Ubc13." Mol. Cell. Biol. 26(23): 8901-8913.
Lis, E. T. and F. E. Romesberg (2006). "Role of Doa1 in the Saccharomyces cerevisiae DNA Damage Response." Mol. Cell. Biol. 26(11): 4122-4133.
Lotz C., et al. (2005) "Targeting Positive Regulatory Domain I-Binding Factor 1 and X Box-Binding Protein 1 Transcription Factors by Multiple Myeloma-Reactive CTL." J. Immunol. 175(2): 1301-1309.
Meisenberg, C., et al. (2011) “Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.” Nucleic Acids Res. 10.1093/nar/gkr744.
Mersman, D.P., et al. (2009) "Poly-ubiquitination of the demethylase Jhd2 controls histone methylation and gene expression." Genes & Dev. 23: 951-962.
Miyase S., et al. (2005) "Differential Regulation of Rad18 through Rad6-dependent mono- and poly-ubiquitination." J. Biol. Chem. 280(1): 515-524.
Mo, P., et al. (2010) “MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3.” J. Biol. Chem. 285: 26908 - 26915.
Ogawa S., et al. (2004) "A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation." PNAS 101(40): 14461-14466.
Oh Y.K., et al. (2008) "Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells." Mol. Canc. Res. 6: 1232-1249.
Pasillas, M., et al. (2011) “NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome.” Human Mutation, 32: 292-298
Pebernard, S., et al. (2008) "Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holo-complex in Genome Stability." Mol. Biol. Cell 19(10): 4099-4109.
Pepbernard S., et al. (2008) "Ku80 removal from DNA through double strand break–induced ubiquitylation." J. Cell. Biol. 182(3):467-479.
Pinato, S., et al. (2011) “UMI, a Novel RNF168 Ubiquitin Binding Domain Involved in the DNA Damage Signaling Pathway.” Molecular and Cellular Biology, 31: 118-126.
Plafker, K.S., et al. (2010) “The Ubiquitin-conjugating Enzyme UbcM2 Can Regulate the Stability and Activity of the Antioxidant Transcription Factor Nrf2.” J. Biol. Chem. 285: 23064 - 23074.
Prager, K., et al. (2007) "A Structural Switch of Presenilin 1 by Glycogen Synthase Kinase 3β-mediated Phosphorylation Regulates the Interaction with β-Catenin and Its Nuclear Signaling." J. Biol. Chem. 282(19): 14083-14093.
Saugar, I., et al. (2011) “The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA.” Nucleic Acids Res. 10.1093/nar/gkr738.
Shao, G., et al. (2009) "MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks." Genes & Dev. 23(6): 740-754.
Shim, M., et al. (2003). "Lithium stabilizes the CCAAT/Enhancer-binding protein α (C/EBPα) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibitor of proteasomal activity." Genes Cells 11(7): 731-744.
Wang B., (2009) NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control." Genes & Dev.pan style="mso-spacerun:yes" 23(6): 729-739.
Wang, H., et al. "Activating Transcription Factor 3 Activates p53 by Preventing E6-associated Protein from Binding to E6." J. Biol. Chem. 285: 13201 - 13210.
Watanabe K., et al. (2004) "Rad18 guides polβ to replication stalling sites through physical interaction and PCNA mono-ubiquitination." EMBO J. 23(19): 3886-3896.
Watanabe, K., et al. (2009) "RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1." Nucleic Acids Res. 37: 2176-2193. "
Wei, W., et al. (2007). "Treatment of cultured myotubes with the proteasome inhibitor beta-lactone increases the expression of the transcription factor C/EBPβ." Am. J. Physiol. Cell Physiol. 292(1): C216-226.
Yan C., et al. (2005) "Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination." EMBO J. 24(13): 2425-2435.
Yanagawa Y., et al. (2004) "Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo/em> and enhances the activity of ubiquitin conjugating enzymes." Genes & Dev. 18(17): 2172-2181.
Yang J., et al. (2005) "Light Regulates COP1-Mediated Degradation of HFR1, a Transcription Factor Essential for Light Signaling in Arabidopsis." Plant Cell 17(3): 804-821.
Yang, Y., et al. (2010) “E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNF-induced JNK activation.” PNAS 107: 13444 - 13449.
Yuasa, M. S., et al. (2006). "A human DNA polymerase-εcomplex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest." Genes Cells 11(7): 731-744.
Zhang D. D., et al. (2005) "Ubiquitination of Keap1, a BTB-Kelch Substrate Adaptor Protein for Cul3, Targets Keap1 for Degradation by a Proteasome-independent Pathway." J. Biol. Chem. 280(34): 30091-30099.
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