ER Trafficking / receptors / signaling
Almeida, C. G., et al. (2006). "β-Amyloid Accumulation Impairs Multivesicular Body Sorting by Inhibiting the Ubiquitin-Proteasome System." J. Neurosci. 26(16): 4277-4288.
Anderson, G.R., et al. (2007). " Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases ." J. Neurosci. 27(51): 14117-14127.
Arimoto, K., et al. (2010) “Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense.” PNAS 107: 15856 - 15861.
Barriere, H., et al. (2007). "Plasticity of Poly-Ubiquitin Recognition as Lysosomal Targeting Signals by the Endosomal Sorting Machinery." Mol. Biol. Cell. 18(10) :3952-3965.
Bergeron, A., et al. (2006). "Involvement of Endoplasmic Reticulum Stress in Hereditary Tyrosinemia Type I." J. Biol. Chem. 281(9): 5329-5334.
Bulut, G., et al. (2011) “Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor.” The Journal of Biological Chemistry, 286: 6449-6457.
Byun, H., et al. (2010) “Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function.” PNAS 107: 12287 - 12292.
Chen, Y., et al. (2006). "Proteasome-dependent down-regulation of activated Stat5A in the nucleus." Blood 108(2): 566-574.
Chung A. S., et al. (2005) "Ankyrin Repeat and SOCS Box 3 (ASB3) Mediates Ubiquitination and Degradation of Tumor Necrosis Factor Receptor II." Mol. Cell. Biol. 25(11): 4716-4726.
Conze, D.B., et al. (2008) “Lys63-Linked Poly-ubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation.” Mol. Cell. Biol. 28: 3538-47.
Cordier, F., et al. (2009) “The Zinc Finger of NEMO Is a Functional Ubiquitin-binding Domain.” J. Biol. Chem. 284(5): 2902-2907.
Coulombe, P., et al. (2003) “Rapid turnover of extracellular signal-regulated Kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.” Mol. Cell. Biol. 23: 4542-
De Schutter, J., et al. (2009) “SHIP2 (SH2 Domain-containing Inositol Phosphatase 2) SH2 Domain Negatively Controls SHIP2 Monoubiquitination in Response to Epidermal Growth Factor.” J. Biol. Chem. 284: 36062 - 36076.
Dudek, J.M. and Horton, R.A. (2010) "TR-FRET Biochemical Assays for Detecting Posttranslational Modifications of p53." J Biomol Screen. 15: 569 - 575.
Esposito, K., et al. (2006). "Rosiglitazone Cools Down Inflammation in the Metabolic Syndrome." Arterioscler. Thromb. Vasc. Biol. 26(6): 1413-1414.
Floyd, Z. E., et al. (2006). "Degradation of STAT5 Proteins in 3T3-L1 Adipocytes is induced by TNFα and cycloheximide in a manner independent of STAT5A activation." Am J Physiol Endocrinol Metab: 292(2):E461-8.
Forbes, A., et al. (2007). "The tetraspan protein EMP2 regulates expression of caveolin-1." J. Biol. Chem.: 282(36): 26542-26551.
Fotia A. B., et al. (2004) "Regulation of Neuronal Voltage-gated Sodium Channels by the Ubiquitin-Protein Ligases Nedd4 and Nedd4-2." J. Biol. Chem. 279(28): 28930-28935.
Fukuda, H., et al. (2006). "MARCH-III Is a Novel Component of Endosomes with Properties Similar to Those of MARCH-II." J. Biochem. (Tokyo) 139(1): 137-145.
Habelhah H., et al. (2004) "Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-κB." EMBO J. 23(2): 322-332.
Hartman, I.Z., et al. (2010) "Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets." J. Biol. Chem. 285: 19288 - 192
Hatao, F., et al. (2004) "Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein." J. Leukoc. Biol. 76(4): 904-908.
Jalonen U, et al. (2008) "Compounds That Increase or Mimic Cyclic Adenosine Monophosphate Enhance Tristetraprolin Degradation in Lipopolysaccharide-Treated Murine J774 Macrophages." J. Pharm. Exp. Ther. 326: 514-522
Jang, I.-C., et al. (2007). "Independent and interdependent functions of LAF1 and HFR1 in phytochrome A signaling." Genes & Dev. 21(16): 2100-2111.
Kaneko, M., et al. (2010) “Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-β Generation.” J. Neurosci., 3924 - 3932.
Kaneko-Oshikawa C., et al. (2005) "Mammalian E4 Is Required for Cardiac Development and Maintenance of the Nervous System." Mol. Cell. Biol. 25(24): 10953-10964.
Kim D. W., et al. (2005) "The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes." PNAS 102(39): 14046-14051.
Kim, S. T., et al. (2006). "Exogenous Free Ubiquitin Enhances Lily Pollen Tube Adhesion to an in Vitro Stylar Matrix and May Facilitate Endocytosis of SCA (Stigma/stylar Cysteine-rich Adhesin)." Plant Physiology: 142: 984-992.
Kostova, Z., et al. (2009) “A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation.” J. Cell Sci. 122: 1374-1381.
Kowanetz K., et al. (2004) "Suppressors of T-cell Receptor Signaling Sts-1 and Sts-2 Bind to Cbl and Inhibit Endocytosis of Receptor Tyrosine Kinases." J. Biol. Chem. 279(31): 32786-32795.
LaLonde, D. and Bretscher, A. (2011) “The UBX Protein SAKS1 Negatively Regulates Endoplasmic Reticulum-associated Degradation and p97-dependent Degradation.” The Journal of Biological Chemistry, 286: 4892-4901.
Lee T. H., et al. (2004) "The Kinase Activity of Rip1 Is Not Required for Tumor Necrosis Factor-α-induced IκB Kinase or p38 MAP Kinase Activation or for the Ubiquitination of Rip1 by Traf2." J. Biol. Chem. 279(32): 33185-33191.
Lilley B. N. and Ploegh H.L. (2005) "Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane." PNAS 102(40): 14296-14301.
Lo, S.-C. and M. Hannink (2006). "CAND1-Mediated Substrate Adaptor Recycling Is Required for Efficient Repression of Nrf2 by Keap1." Mol. Cell. Biol. 26(4): 1235-1244.
Lu, J., et al. (2011) “RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation.” J. Biol. Chem. 286: 24426 - 24433.
Mansouri, M., et al. (2006). "Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells." Blood 108(6): 1932-1940.
Marfella, R., et al. (2006). "Increased Activity of the Ubiquitin-Proteasome System in Patients With Symptomatic Carotid Disease Is Associated With Enhanced Inflammation and May Destabilize the Atherosclerotic Plaque: Effects of Rosiglitazone Treatment."
Marfella, R., et al. (2006). "The Ubiquitin-Proteasome System and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Rosiglitazone Treatment." Diabetes 55(3): 622-632.
Medina E. A., et al. (2005) "Tumor Necrosis Factor-α Decreases Akt Protein Levels in 3T3-L1 Adipocytes via the Caspase-Dependent Ubiquitination of Akt." Endocrinology 146(6): 2726-2735.
Mizuno, E., et al. (2003) “STAM proteins bind uibuiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif.” Mol. Cell. Biol. 14(9): 3675-3689.
Nelson, R. F., et al. (2006). "A Novel Route for F-box Protein-mediated Ubiquitination Links CHIP to Glycoprotein Quality Control." J. Biol. Chem. 281(29): 20242-20251.
Ogawa S., et al. (2004) "A nuclear receptor co-repressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation." PNAS 101(40): 14461-14466.
Oved, S., Y. Mosesson, et al. (2006). "Conjugation to Nedd8 Instigates Ubiquitylation and Down-regulation of Activated Receptor Tyrosine Kinases." J. Biol. Chem. 281(31): 21640-21651.
Saini, V., et al. (2010) "CXC Chemokine Receptor 4 Is a Cell Surface Receptor for Extracellular Ubiquitin." J. Biol. Chem. 285: 15566 - 15576.
Shah, O. J. and T. Hunter (2006). "Turnover of the Active Fraction of IRS1 Involves Raptor-mTOR- and S6K1-Dependent Serine Phosphorylation in Cell Culture Models of Tuberous Sclerosis." Mol. Cell. Biol. 26(17): 6425-6434.
Song B.-L. and DeBose-Boyd R.A. (2004) "Ubiquitination of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Permeabilized Cells Mediated by Cytosolic E1 and a Putative Membrane-bound Ubiquitin Ligase." J. Biol. Chem. 279(27): 28798-28806.
Song, B.-L. and R. A. DeBose-Boyd (2006). "Insig-dependent Ubiquitination and Degradation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Stimulated by δ- and γ-Tocotrienols." J. Biol. Chem. 281(35): 25054-25061.
Sun, Z., et al. (2007). "Keap1 Controls Post-Induction Repression of the Nrf2-Mediated Antioxidant Response by Escorting Nuclear Export of Nrf2." Mol. Cell. Biol.: 27(18):6334-6349.
Wang H., et al. (2004) "Both the PPPY and PTAP Motifs Are Involved in Human T-Cell Leukemia Virus Type 1 Particle Release." J. Virol. 78(3): 1503-1512.
Wang, X.H., et al. “Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity.” J. Biol. Chem. 285: 21249 - 21257.
Wyatt, D., et al. (2011) “Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor Trafficking.” The Journal of Biological Chemistry, 286: 3884-3893.
Zvonic S., et al. (2005) "Cross-talk among gp130 Cytokines in Adipocytes." J. Biol. Chem. 280(40): 33856-33863.
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