Proteasome

Proteosomes are distributed throughout eukaryotic cells at a high concentration and are the primary sites for protein degradation in mammalian cells. Substrate proteins linked to poly-ubiquitin chains are recognized for proteolytic degradation by the proteasome and recycling of ubiquitin monomers by deubiquitinating enzymes.


Enzymes
E-366

19S Proteasome

human

25 μg

$300 Buy / Info
E-375

20S Immunoproteasome

rat

50 μg

$250 Buy / Info
E-380

PA28 Activator alpha subunit

human recombinant 100 μg $180 Buy / Info
E-350

20S Proteasome

rabbit

25 μg 50 μg

$80 $125 Buy / Info
E-352

20S Proteasome

rat 50 μg $125 Buy / Info
E-355

20S Proteasome

mouse

50 μg

$125 Buy / Info
E-358

20S Proteasome

canine

50 μg

$125 Buy / Info
E-360

20S Proteasome

human

50 μg

$150 Buy / Info
E-365

26S Proteasome

human

25 μg 50 μg

$175 $300 Buy / Info
E-370

20S Immunoproteasome

human

25 μg

$180 Buy / Info
E-376

20S Immunoproteasome

mouse

50 μg

$250 Buy / Info
E-377

20S Immunoproteasome

canine 25 μg $180 Buy / Info
E-382

His6-PA28 Activator beta subunit

human recombinant

100 μg

$180 Buy / Info
E-384

His6-PA28 Activator gamma subunit

human recombinant

100 μg

$180 Buy / Info
Inhibitors
I-100

clasto-Lactacystin beta Lactone

Synthetic 200 μg $300 Buy / Info
I-102

clasto-Lactacystin beta Lactone

Synthetic 1 mg $1,200 Buy / Info
I-110

Epoxomicin

synthetic 200 μg $300 Buy / Info
I-112

Epoxomicin

synthetic 1 mg $1,200 Buy / Info
I-114

Lactacystin

synthetic

200 μg

$229 Buy / Info
I-115

Lactacystin

synthetic 500 μg $300 Buy / Info
I-116

Lactacystin

synthetic 1 mg $550 Buy / Info
I-120

Z-Leu-Leu-Leu-B(OH)2 (MG-262)

Synthetic 200 μg $225 Buy / Info
I-122

Z-Leu-Leu-Leu-B(OH)2 (MG-262)

Synthetic 1 mg $925 Buy / Info
I-130

Z-Leu-Leu-Leu-CHO (MG-132)

Synthetic 1 mg 5mg $30 $70 Buy / Info
I-135

Z-Leu-Leu-Nva-CHO (MG-115)

Synthetic 5mg $70 Buy / Info
I-140

Z-lle-Glu(OtBu)-Ala-Leu-CHO (Z-IE-OtBu-AL-CHO)

Synthetic 5mg $110 Buy / Info
I-150

Z-Leu-Leu-Phe-CHO (Z-LLF-CHO)

Synthetic 1 mg $45 Buy / Info
I-160

Ac-Leu-Leu-Nle-CHO (MG-101)

Synthetic 5 mg $40 Buy / Info
I-170

Ac-Leu-Leu-Met-CHO (Ac-LLM-CHO)

Synthetic 5 mg $30 Buy / Info
I-185

AM 114

Synthetic

10 mg

 50 mg

$105 $449 Buy / Info
I-190

Me4BodipyFL-Ahx3Leu3VS (Proteasome Activity Probe)

Synthetic 50 μg $300 Buy / Info
I-195

Gliotoxin

Synthetic

1 mg

$79 Buy / Info
Substrates
S-220

Z-Leu-Leu-Leu-AMC (Z-LLL-AMC)

Synthetic

5 mg

$120 Buy / Info
S-230

Z-Leu-Leu-Glu-AMC (Z-LLE-AMC)

Synthetic

5 mg

$120 Buy / Info
S-260

Suc-Leu-Tyr-AMC (Suc-LY-AMC)

Synthetic

5 mg

$20 Buy / Info
S-280

Suc-Leu-Leu-Val-Tyr-AMC (Suc-LLVY-AMC)

Synthetic

5 mg

$65 Buy / Info
S-290

Ac-Arg-Leu-Arg-AMC (Ac-RLR-AMC)

Synthetic

5 mg

$230 Buy / Info
S-300

Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC)

Synthetic 5 mg $70 Buy / Info
Antibodies by R&D Systems
AF5540

Mouse S5a/Angiocidin Affinity Purified Polyclonal Ab

Mouse

100 µg

$355 Buy / Info