E3 Ligase

Ubiquitin modification of substrate proteins is achieved by the activity of E1 activating, E2 conjugating and E3 ligase enzymes. Substrate proteins can be modified with one (mono-ubiquitination) or many (poly-ubiquitination) molecules of ubiquitin, and each type of modification has distinct regulatory fates. E3 ligases number in the thousands and have the highest level of specificity for the target protein to be modified by ubiquitin or ubiquitin-like modifiers (UBL).


Accessory Proteins
AP-100

HSP70/HSPA1A

Human recombinant, bacteria-derived

50 µg, 100 µg

$285 $355 Data Sheet Buy / Info
AP-110

DNAJB1/HSP40

Human recombinant, bacteria-derived

50 µg

$159 Data Sheet Buy / Info
AP-120

E6, Human Papillomavirus type 16

Viral Recombinant, bacteria derived

25 μg

$125 Data Sheet Buy / Info
AP-140

HSP60/HSPD1

Human recombinant, bacteria-derived

50 µg

$249 Data Sheet Buy / Info
AP-150

HSP10/HSPE1

Human recombinant, bacteria-derived

50 µg

$249 Data Sheet Buy / Info
AP-160

HSP90α/HSP90AA1

Human recombinant, bacteria-derived

50 µg

$259 Data Sheet Buy / Info
AP-180

PINK1 Kinase

T. castaneum Recombinant

100 µg

$329 Data Sheet Buy / Info
AP-182
New

PINK1 Kinase

Pediculus humanus recombinant

100 µg

$329 Data Sheet Buy / Info
SP-480

His6-α-Synuclein

Human Recombinant

500 µg

$339 Data Sheet Buy / Info
SP-485
New

α-Synuclein

Human Recombinant

500 µg

$379 Data Sheet Buy / Info
SP-490
New

Miro1

Human Recombinant

100 µg

$195 Data Sheet Buy / Info
Activity Kits
K-102

MuRF1/TRIM63 Ubiquitin Ligase Kit - S5a Substrate

Human Recombinant

1 Kit

$395 Data Sheet Buy / Info
K-200B

Mdm2/HDM2 Ubiquitin Ligase Kit - p53 Substrate

Human Recombinant

1 Kit

$565 Data Sheet Buy / Info
K-210

Mdm2/HDM2 Ubiquitin Ligase Kit - S5a Substrate

Human Recombinant

1 Kit

$475 Data Sheet Buy / Info
K-220

RNF4 Ubiquitin Ligase Kit - di-SUMO3 Substrate

Human Recombinant

1 Kit

$325 Data Sheet Buy / Info
K-230

E6AP Ubiquitin Ligase Kit - S5a Substrate

Human Recombinant

1 Kit

$395 Data Sheet Buy / Info
K-240

E6AP/E6 Ubiquitin Ligase Kit - p53 Substrate

Human Recombinant

1 Kit

$495 Data Sheet Buy / Info
K-250

XIAP Ubiquitin Ligase Kit - Diablo Substrate

Human Recombinant

1 Kit

$395 Data Sheet Buy / Info
K-260

cIAP-1/HIAP2 Ubiquitin Ligase Kit

human recombinant

1 Kit

$355 Data Sheet Buy / Info
K-270

ITCH/AIP4 Ubiquitin Ligase Kit

Human Recombinant

kit

$395 Data Sheet Buy / Info
K-280

CHIP Ubiquitin Ligase Kit - Glow-Fold Substrate

Human Recombinant

1 Kit

$455 Data Sheet Buy / Info
K-290

HSP70/HSP40 Glow-Fold Protein Refolding Kit

Human Recombinant

1 Kit

$475 Data Sheet Buy / Info
K-300

HSP60/HSP10 Glow-Fold Protein Refolding Kit

Human Recombinant

1 Kit

$475 Data Sheet Buy / Info
Enzymes
E3-160

Parkin

Human Recombinant

25 µg

$349 Data Sheet Buy / Info
E3-162
New

Parkin, W403A

Human Recombinant

25 µg

$299 Data Sheet Buy / Info
E3-164
New

Parkin, C431S

human recombinant

100 µg

$299 Data Sheet Buy / Info
E3-166
New

Parkin, pS65

human recombinant

25 µg

$369 Data Sheet Buy / Info
E3-202

GST-Mdm2/HDM2

Human Recombinant

50 µg

$279 Data Sheet Buy / Info
E3-204

Mdm2/HDM2

Human Recombinant

50 µg

$325 Data Sheet Buy / Info
E3-210

RNF4

Human Recombinant

50 µg

$269 Data Sheet Buy / Info
E3-220

CHIP/Stub1

Human Recombinant

50μg

$269 Data Sheet Buy / Info
E3-230

E6AP/UBE3A

Human Recombinant

50 μg

$279 Data Sheet Buy / Info
E3-240

His6-MBP-HOIP Catalytic Domain

Human Recombinant

100 µg

$269 Data Sheet Buy / Info
E3-250

NleL Catalytic Domain

E. coli Recombinant

100 µg

$269 Data Sheet Buy / Info
E3-260

ITCH/AIP4, isoform 2

Human Recombinant

100 µg

$275 Data Sheet Buy / Info
E3-280
New

cIAP-1/HIAP-2

Human recombinant, bacteria-derived

50 µg

$179 Data Sheet Buy / Info
E3-290
New

His6-NEDD4

human recombinant

50 µg

$269 Data Sheet Buy / Info
Inhibitors
I-440 proTAME - E3 Ligase, APC/C 1 mg $215 Data Sheet Buy / Info
I-444

Apcin

5 mg vial

$155 Data Sheet Buy / Info