Proteasome

Lithium stabilizes the CCAAT/Enhancer-binding protein [alpha] (C/EBP[alpha]) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibitor of proteasomal activity.

Shim, M., et al. (2003). "Lithium stabilizes the CCAAT/Enhancer-binding protein [alpha] (C/EBP[alpha]) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibitor of proteasomal activity." Genes Cells 11(7): 731-744.

PubMed ID: 
12668682
Product(s) Referenced: 
MG-132

Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis.

Pham, L.V., et al. (2003). "Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis." J. Immunol. 171:88-95.

PubMed ID: 
12816986
Product(s) Referenced: 
20S proteasome

HSP27 is a ubiquitin-binding protein involved in I-κB[alpha] proteasomal degradation.

Parcellier, A., et al. (2003). "HSP27 is a ubiquitin-binding protein involved in I-κB[alpha] proteasomal degradation." Mol. Cell. Biol. 23(11):5790-5802 .

PubMed ID: 
12897149
Product(s) Referenced: 
26S proteasome

Abnormally high expression of proteasome activator-γ in thyroid neoplasm.

Okamura, T., et al. (2003) "Abnormally high expression of proteasome activator-γ in thyroid neoplasm." Clin. Endocrin. Metab. 88(3): 31374031383.

PubMed ID: 
12629132
Product(s) Referenced: 
clasto-lactacystin [beta]-lactone (I-100)

Autoubiquitylation of the V(D)J recombinase protein RAG1.

Jones, J.M., et al. (2003) "Autoubiquitylation of the V(D)J recombinase protein RAG1." PNAS 100(26): 15446-15451.

PubMed ID: 
14671314
Product(s) Referenced: 
clasto-lactacystin-[beta]-lactone

Ataxin-3 interactions with Rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis.

Doss-Pepe, E.W., et al. (2003). "Ataxin-3 interactions with Rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis." Mol. Cell. Biol 23(18): 6469-6483.

PubMed ID: 
12944474
Product(s) Referenced: 
Suc-LLVY-AMC

Rapid turnover of extracellular signal-regulated Kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.

Coulombe, P., et al. (2003) “Rapid turnover of extracellular signal-regulated Kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.” Mol. Cell. Biol. 23: 4542- .

PubMed ID: 
12808096
Product(s) Referenced: 
lactacystin

Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex.

Zhang D. D., et al. (2004) "Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex." Mol. Cell. Biol. 24(24): 10941-10953.

PubMed ID: 
15572695
Product(s) Referenced: 
MG132

Degradation of Fodrin by m-Calpain in Fibroblasts Adhering to Fibrillar Collagen I Gel.

Sato K., et al. (2004) "Degradation of Fodrin by m-Calpain in Fibroblasts Adhering to Fibrillar Collagen I Gel." J. Biochem. (Tokyo) 136(6): 777-785.

PubMed ID: 
15671488
Product(s) Referenced: 
lactacystin

Mass Spectrometric and Mutational Analyses Reveal Lys-6-linked Polyubiquitin Chains Catalyzed by BRCA1-BARD1 Ubiquitin Ligase.

Nishikawa H., et al. (2004) "Mass Spectrometric and Mutational Analyses Reveal Lys-6-linked Polyubiquitin Chains Catalyzed by BRCA1-BARD1 Ubiquitin Ligase." J. Biol. Chem. 279(6): 3916-3924.

PubMed ID: 
Mass Spectrometric and Mutational Analyses Reveal Lys-6-linked Polyubiquitin Chains Catalyzed by BRCA1-BARD1 Ubiquitin Ligase.
Product(s) Referenced: 
26 S proteasome
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