Proteasome

Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration.

Balastik, M., et al. (2008) "Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration." PNAS 105 (33): 12016-12021.

PubMed ID: 
18687884
Product(s) Referenced: 
MG-132

High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources.

Ausseil, F., et al. (2007). "High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources." J. Biomol. Screen. 12(1): 106-116.

PubMed ID: 
17175525
Product(s) Referenced: 
Epoxomicin

Evidence for Cytosolic p27kip1 Ubiquitylation and Degradation during Adipocyte Hyperplasia.

Auld, C. A. and R. F. Morrison (2006). "Evidence for Cytosolic p27kip1 Ubiquitylation and Degradation during Adipocyte Hyperplasia." Obesity 14: 2136-2144.

PubMed ID: 
17189539
Product(s) Referenced: 
epoxomycin

Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.*.

PubMed ID: 
21177809
Product(s) Referenced: 
proteasome inhibitor MG132

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.

Arias E. E. and Walter J.C. (2005) "Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts." Genes & Dev. 19(1): 114-126.

PubMed ID: 
20724660
Product(s) Referenced: 
MG132

Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

PubMed ID: 
21364033
Product(s) Referenced: 
MG-132

Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.

Anderson, G.R., et al. (2007). "Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases." J. Neurosci. 27(51): 14117-14127.

Product(s) Referenced: 
lactacystin

Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation.

Lamothe, B., et al. (2007). "Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation." J. Biol. Chem. 282(6):Determinant of I 4102-4112.

PubMed ID: 
17135271
Product(s) Referenced: 
WT ubiquitin
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