Inhibitor

Proteasome Inhibition Triggers Activity-Dependent Increase in the Size of the Recycling Vesicle Pool in Cultured Hippocampal Neurons.

Willeumier, K., et al. (2006). "Proteasome Inhibition Triggers Activity-Dependent Increase in the Size of the Recycling Vesicle Pool in Cultured Hippocampal Neurons." J. Neurosci. 26(44): 11333-11341.

PubMed ID: 
17079661
Product(s) Referenced: 
clasto-lactacystin [beta]-lactone

Treatment of cultured myotubes with the proteasome inhibitor [beta]-lactone increase expression of the transcription factor C/EBP[beta].

Wei, W., et al. (2006). "Treatment of cultured myotubes with the proteasome inhibitor [beta]-lactone increase expression of the transcription factor C/EBP[beta]." Am J Physiol Cell Physiol: 292:C216-C226.

PubMed ID: 
16987992
Product(s) Referenced: 
Clasto-lactacystin beta-lactone

Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys.

Wang, Z.Q., et al. (2009) "Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys." Diabetes 58: 1488-1498.

PubMed ID: 
19336678
Product(s) Referenced: 
epoxomicin

Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.

Wang, X., et al. (2009) “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

PubMed ID: 
19951915
Product(s) Referenced: 
MG132

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3.

Wang, X., et al. (2007). "Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3." J. Cell Biol. 177(4): 613-624.

Product(s) Referenced: 
MG132

The Viral E3 Ubiquitin Ligase mK3 Uses the Derlin/p97 Endoplasmic Reticulum-associated Degradation Pathway to Mediate Down-regulation of Major Histocompatibility Complex Class I Proteins.

Wang, X., et al. (2006). "The Viral E3 Ubiquitin Ligase mK3 Uses the Derlin/p97 Endoplasmic Reticulum-associated Degradation Pathway to Mediate Down-regulation of Major Histocompatibility Complex Class I Proteins." J. Biol. Chem. 281(13): 8636-8644.

PubMed ID: 
16446359
Product(s) Referenced: 
MG132

SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

PubMed ID: 
21807946
Product(s) Referenced: 
MG132

Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3.

Todi, S.V., et al. (2009) "Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3.” The EMBO journal 28(4): 372–382.

PubMed ID: 
19153604
Product(s) Referenced: 
lactacystin

Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity.

Todi, S. V., et al. (2007). "Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity." J. Biol. Chem.: 282(40): 29348-29358.

PubMed ID: 
17693639
Product(s) Referenced: 
lactacystin

Inducible Nitric-oxide Synthase and Nitric Oxide Donor Decrease Insulin Receptor Substrate-2 Protein Expression by Promoting Proteasome-dependent Degradation in Pancreatic [beta]-Cells: INVOLVEMENT OF GLYCOGEN SYNTHASE KINASE-3[beta].

Tanioka, T., et al. (2011) “Inducible Nitric-oxide Synthase and Nitric Oxide Donor Decrease Insulin Receptor Substrate-2 Protein Expression by Promoting Proteasome-dependent Degradation in Pancreatic [beta]-Cells: INVOLVEMENT OF GLYCOGEN SYNTHASE KINASE-3[beta].” J.

PubMed ID: 
21700708
Product(s) Referenced: 
lactacystin
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