Inhibitor

Newly Discovered Viral E3 Ligase pK3 Induces Endoplasmic Reticulum-associated Degradation of Class I Major Histocompatibility Proteins and Their Membrane-bound Chaperones.

Herr, R.A. et al. (2012) "Newly Discovered Viral E3 Ligase pK3 Induces Endoplasmic Reticulum-associated Degradation of Class I Major Histocompatibility Proteins and Their Membrane-bound Chaperones." J. Biol. Chem. 287(18): 14467–14479.

PubMed ID: 
22403403
Product(s) Referenced: 
deubiquiting enzyme inhibitor ubiquitin aldehyde, proteasome inhibitor MG132

White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor via Ubiquitination.

He, F., B. J. Fenner, et al. (2006). "White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor via Ubiquitination." J. Virol. 80(8): 3884-3892.

PubMed ID: 
16571805
Product(s) Referenced: 
MG132

Cross-talk among gp130 Cytokines in Adipocytes.

Zvonic S., et al. (2005) "Cross-talk among gp130 Cytokines in Adipocytes." J. Biol. Chem. 280(40): 33856-33863.

PubMed ID: 
16096272
Product(s) Referenced: 
Epoxomicin

Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex.

Zhang D. D., et al. (2004) "Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex." Mol. Cell. Biol. 24(24): 10941-10953.

PubMed ID: 
15572695
Product(s) Referenced: 
MG132

Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress.

Zhang D. D., et al. (2003) "Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress." Mol. Cell. Biol. 23(22): 8137-8151.

PubMed ID: 
14585973
Product(s) Referenced: 
MG132

Clenbuterol induces muscle-specific attenuation of atrophy through effects on the ubiquitin-proteasome pathway.

Yimlamai T., et al. (2005) "Clenbuterol induces muscle-specific attenuation of atrophy through effects on the ubiquitin-proteasome pathway." J Appl Physiol 99(1): 71-80.

PubMed ID: 
15774696
Product(s) Referenced: 
lactacystin

Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication.

Yang Z., et al. (2008) "Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication." J. Virol. 82: 3590-603.

Product(s) Referenced: 
Ub aldehyde

Unique Biologic Properties of Recombinant AAV1 Transduction in Polarized Human Airway Epithelia.

Yan, Z., et al. (2006). "Unique Biologic Properties of Recombinant AAV1 Transduction in Polarized Human Airway Epithelia." J. Biol. Chem. 281(40): 29684-29692.

PubMed ID: 
16899463
Product(s) Referenced: 
MG101

Ubiquitination of E3 ligase TRIM5[alpha] and its potential role.

Yamauchi, K., et al. (2008). "Ubiquitination of E3 ligase TRIM5[alpha] and its potential role." FEBS J. 275(7): 1540-1555.

PubMed ID: 
18312418
Product(s) Referenced: 
MG115

NARF, an emo-like Kinase (NLK)-associated Ring Finger Protein Regulates the Ubiquitylation and Degradation of T Cell Factor/Lymphoid Enhancer Factor (TCF/LEF).

Yamada, M., J. Ohnishi, et al. (2006). "NARF, an emo-like Kinase (NLK)-associated Ring Finger Protein Regulates the Ubiquitylation and Degradation of T Cell Factor/Lymphoid Enhancer Factor (TCF/LEF)." J. Biol. Chem. 281(30): 20749-20760.

PubMed ID: 
16714285
Product(s) Referenced: 
ubiquitin aldehyde
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