Material Data Sheet

SUMO3 Mutant K11R

Price: $195.00
Catalog #: ULM-762

SUMO3 Mutant K11R

250 µg

Mutation of lysine 11 to arginine renders SUMO-3 unable to form poly-SUMO multimers and is useful to investigate mono-SUMOylation or can be used to reduce poly-SUMO chain formation. Human SUMO-3 contains the VK11TE sequence which allows for the formation of poly-SUMO chains. K11 is the conserved lysine that becomes modified and is the point of attachment for the C-terminal glycine of the preceding SUMO-3. The function of SUMO chains has not yet been fully elucidated.

Product Information

X mg/ml (XμM) in 50 mM HEPES pH 8.0, 150 mM NaCl, 1mM DTT. Actual concentration varies with lot number.
10.5 kDa
> 95% by SDS-PAGE

Use & Storage

Typical in vitro concentrations for conjugate formation is 10-50 μM depending on conditions. 
Store at -80°C once reconstituted. Avoid multiple freeze/thaw cycles.



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