UL-701

Material Data Sheet

SUMO1 Aldehyde

Price: $200.00
Catalog #: UL-701

SUMO1 Aldehyde

Price: 
$200
Quantity: 
50 μg
Data Sheet: 
application/pdf iconUL701 SUMO aldehyde.pdf
Stock: 

X mg/ml (X mM) in 50 mM Mes pH 5.5, 150mM NaCl

MW: 
11.1 kDa
Purity: 
> 98 % by HPLC.
Solubility: 
Soluble in DMSO up to 5 mg/ml. For best results, pellet dry compound prior to reconstitution.
Supplied: 

This is a lyophilized powder

Also known as: SUMO-H

A potent and highly specific inhibitor of SUMO-specific isopeptidases (SENPs). This protein blocks the hydrolysis of poly-SUMO chains on substrate proteins in vitro and thus enhances poly-SUMO chain accumulation.

Use & Storage

Use: 

Add directly to in vitro assay from the stock solution. Depending on conditions and detection method, typical concentrations to fully inhibit ISG15 deconjugating enzymes in vitro are 1-5 μM.

Storage: 
Store powder at -20°C. Store stock solution at -80°C. Avoid multiple freeze/thaw cycles.solubilization. Avoid multiple freeze/thaw cycles.

Literature

References: 

Hemelaar J., et al. (2004) Mol.Cell.Biol. 24: 84-95