Material Data Sheet
Peptide aldehydes form a covalent hemiacetal adduct with the 20S proteasome, inhibiting the chymotrypsin-like peptidase activity. These inhibitors are reversible and cell-permeable, and also inhibit the activity of calpains and cathepsins.
Purity:> 95% by HPLC.
Solubility:Soluble and stable in DMSO up to 15 mg/ml.
20S proteasome Ki=350 nM
Store DMSO stock at -20°C. Avoid multiple freeze/thaw cycles.
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