E3-502

New
Material Data Sheet

DDB1/DCAF16 Complex, His-tag, FLAG-tag

Price: $285.00
Catalog #: E3-502

DDB1/DCAF16 Complex, His-tag, FLAG-tag

Price: 
$285
Quantity: 
25 µg
Data Sheet: 

 

DDB1- and CUL4-associated factor 16 (DCAF16) is a putative substrate receptor for an E3 Ubiquitin ligase located in the cell nucleus.  A new class of electrophilic ligand-dependent protein degraders that function through DCAF16 has recently been described.  DCAF16 is a component of DCX (DDB1-CUL4-X-box) ligase complexes that mediate the ubiquitination of numerous target proteins including the transcriptional regulator MEIS2.  This product consists of a FLAG-tagged DDB1 (UniProt Q16531) and His-tagged DCAF16 (UniProt Q9NXF7).

Product Information

Stock: 
X mg/ml (X µM) in 50 mM HEPES pH 7.5, 200 mM NaCl, 10% (v/v) Glycerol, 1 mM DTT
MW: 
131 kDa (DDB1), 27 kDa (DCAF16)
Purity: 
> 95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain
Storage: 

Store at -80°C and avoid freeze/thaw cycles