E3-501

New
Material Data Sheet

DDB1

Price: $351.00
Catalog #: E3-501

DDB1

Price: 
$351
Quantity: 
50 µg
Data Sheet: 

DNA damage-binding protein 1 (DDB1) is a component of the UV-damaged DNA binding (UV-DDB) complex which minimally consists of DDB1 and DDB2.  At 1,140 amino acids in length and a predicted molecular weight of 127 kDa, human DDB1 is 99% identical to both its mouse and rat orthologues.  DDB1 is also a component of DCX (DDB1-CUL4-X-box) E3 Ubiquitin Ligase complexes where it serves to associate the Cullin-4 subunit to substrate recognition subunits such as Cereblon (CRBN), and various DCAF (DDB1-CUL4 Associate Factor) proteins.  This recombinant DDB1 (UniProt Q16531) is untagged.

Product Information

Stock: 
X mg/ml (X µM) in 50 mM HEPES pH 7.5, 200 mM NaCl, 10% (v/v) Glycerol, 1 mM DTT
MW: 
127 kDa
Purity: 
>95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue Stain
Storage: 

Store at -80°C.