E2-695

Material Data Sheet

His6-UBE2T

Price: $229.00
Catalog #: E2-695

His6-UBE2T

Price: 
$229
Quantity: 
100 µg
Data Sheet: 

UBE2T (HSPC150) was cloned from CD34-positive hematopoietic stem cells. UBE2T homologs are only found in vertebrates and have widespread expression. UBE2T is the E2 enzyme which is essential for the Fanconi anemia pathway, required for the efficient repair of damaged DNA. UBE2T binds to FANCL, the Ubiquitin ligase subunit of the Fanconi anemia core complex, and is required for the mono-Ubiquitination of FANCD2 in vivo.

Product Information

Stock: 
X mg/ml (X μM) in 50 mM HEPES pH 6.8, 50 mM NaCl, 10% (v/v) Glycerol, 1 mM DTT
MW: 
25 kDa
Purity: 
> 95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain

Use & Storage

Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.