E2-622

Material Data Sheet

UbcH5b/UBE2D2

Price: $229.00
Catalog #: E2-622

UbcH5b/UBE2D2

Price: 
$229
Quantity: 
100 µg
Data Sheet: 
UbcH5 enzymes are human homologs of the yeast UBC4/5 family and play many important regulatory roles in inflammation and cancer. UbcH5b mediates the degradation of a myriad short-lived regulatory proteins (such as p53 in the presence of E6/E6AP or MDM2, c-Fos, IκBα, p105) and abnormal proteins. UbcH5b has 89% and 88% sequence identity with UbcH5a and UbcH5c respectively.

Product Information

Stock: 
X mg/ml (X μM) in 50 mM HEPES pH 7.5, 100 mM NaCl, 10% (v/v) Glycerol
MW: 
17 kDa
Purity: 
> 95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain

Use & Storage

Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.