E2-607

Material Data Sheet

UbcH2/UBE2H

Price: $229.00
Catalog #: E2-607

UbcH2/UBE2H

Price: 
$229
Quantity: 
100 µg
Data Sheet: 

This E2 enzyme encodes for the human homolog of the yeast Ubc8 gene. UbcH2 can conjugate ubiquitin to histone H2A in an E3-independent manner in vitro. This E2 enzyme is also involved in the ubiquitination of N-end rule pathway substrates, and may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Product Information

Stock: 
X mg/ml (X μM) in 50 mM HEPES pH 8.0, 100 mM NaCl, 10% (v/v) Glycerol
MW: 
17 kDa
Purity: 
> 95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain

Use & Storage

Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.