E-598

Material Data Sheet

MYSM1

Price: $269.00
Catalog #: E-598

MYSM1

Price: 
269
Quantity: 
50 µg
Data Sheet: 
application/pdf icone-598.pdf

Histone H2A deubiquitinase MYSM1 is a specialized metalloprotease with a predicted molecular weight of 95 kDa. MYSM1 is a member of the peptidase M67A family and the human protein shares 79% amino acid sequence identity with its mouse ortholog. MYSM1 has been reported to function within a large chromatin remodeling complex, containing itself, PCAF, RBM10, TRIP5, and possibly other proteins. MYSM1 plays roles in hematopoiesis and lymphocyte differentiation, stem cell maintenance, and innate immunity.

Product Information

Stock: 
X mg/ml (X µM) in 50 mM HEPES pH 7.5, 100 mM NaCl, 10% (v/v) Glycerol,    2 mM TCEP
MW: 
95 kDa
Purity: 
> 90% by SDS-PAGE

Use & Storage

Use: 

Reaction conditions will need to be optimized for each specific application. We recommend an initial recombinant human MYSM1 concentration of 20-100 nM when using Ubiquitin-AMC or Ubiquitin-Rh110 substrates (U-550, U-555).

Storage: 

Store at -80ºC.  Avoid freeze-thaw cycles.