E-560

Material Data Sheet

His6-ZRANB1/Trabid

Price: $269.00
Catalog #: E-560

His6-ZRANB1/Trabid

Price: 
$269
Quantity: 
50 µg
Data Sheet: 

Zinc Finger, RAN-binding Domain Containing 1 (ZRANB1), also known as TRAF-binding Domain-containing Protein (Trabid), is a C64 type peptidase and a member of the ovarian tumor (OTU) protein super-family with a predicted molecular weight of 81 kDa (1). The human protein shares 99% amino acid sequence identity with its mouse ortholog. ZRANB1 preferentially cleaves K29-, K33-, and K63-linked poly-Ubiquitin chains (2). It has been shown to play a role in the regulation of Wnt signaling via deubiquitination of APC (3,4). This recombinant protein contains a C-terminal 6-His tag.

Product Information

Stock: 
X mg/ml (X mM) in 50 mM Hepes pH 8.0, 100 mM NaCl, 1 mM TCEP
MW: 
82 kDa
Purity: 
> 95% by SDS-PAGE

Use & Storage

Use: 

Typical enzyme concentration for use in vitro ranges from 0.1-1 mM depending on conditions and substrate.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.