E-554

Material Data Sheet

His6-Otubain-2, isoform 1

Price: $109.00
Catalog #: E-554

His6-Otubain-2, isoform 1

Price: 
$109
Quantity: 
50 µg

Otubain-2 is a C65 type peptidase and a member of the ovarian tumor (OTU) protein super-family found in eukaryotes, viruses and pathogenic bacterium.  Otubain-2 associates with the E3 ubiquitin ligases TRAF3 and TRAF6, and has been shown to negatively regulate virus-induced type I IFN induction and the antiviral responses mediated by these ligases.  This recombinant protein contains a C-terminal 6-His tag.

Product Information

Stock: 
X mg/ml (X µM) in 50 mM Hepes, pH 8.0, 150mM NaCl, 5mM DTT
MW: 
28 kDa
Purity: 
>90% by SDS-PAGE

Use & Storage

Use: 

Typical enzyme concentration for use in vitro ranges from 0.1-2 µM depending on conditions and substrate.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.

Literature

References: 

Li S., et al. (2010) J.Biol.Chem. 285: 4291-4297

Nanao M.H., et al. (2004) EMBO Reports 5: 783-788