AP-100

Material Data Sheet

HSP70/HSPA1A

Price: $285.00
Catalog #: AP-100

HSP70/HSPA1A

Price: 
$285 $355
Quantity: 
50 µg, 100 µg
Data Sheet: 

Heat shock proteins (HSPs) are a family of highly conserved stress response proteins.  Heat shock proteins function primarily as molecular chaperones by facilitating the folding of other cellular proteins, preventing protein aggregation or targeting improperly folded proteins to specific degradative pathways.  HSPs are typically expressed at low levels under normal physiological conditions, but are dramatically up-regulated in response to cellular stress.  HSP70 is a 72 kDa member of the heat shock protein 70 family of proteins, and is also known as HSPA1A, HSP70-1, and HSP72.  HSP70 and HSP40 are required to target some misfolded proteins to the Ubiquitin E3 ligase CHIP (Stub1) for subsequent ubiquitination.

Product Information

Stock: 
X mg/ml (X µM) in 50 mM Hepes pH 8.0, 100 mM NaCl, 5 mM DTT
MW: 
70 kDa
Purity: 
> 95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain

Use & Storage

Use: 

Typical enzyme concentration for use in vitro is dependent on specific application.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.