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Material Data Sheet
UbcH10/UBE2C Polyclonal Ab
Price: $150.00
UbcH10/UBE2C Polyclonal Ab
Price:
150
Quantity:
200 µL
Data Sheet:
UbcH10 is an essential mediator of mitotic destruction events and cell cycle progression. It catalyzes the destruction of cyclins A and B in conjunction with the anaphase-promoting complex. This activity is essential at the end of mitosis for the inactivation of their partner kinase
Cdc2 and exit from mitosis into G1 of the next cell cycle.
Product Information
Stock:
PBS pH 7.4, 20% glycerol.
Antigen:
Full-length, highly purified human UbcH10 protein. Use & Storage
Use:
Recommended dilution range for Western blot analysis is 1:100 to 1:1000. Non-functional for immunoprecipitation.
Storage:
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Literature
References:
Bastians H., et al. (1999) Mol. Biol. Cell. 10:3927-3941
Hershko A. and Ciechanover A. (1998) Ann. Rev. Biochem. 67:425-479
Lin Y., et al. (2002) J. Biol. Chem. 277:21913-21921
Okamoto Y., et al. (2003) Canc. Res. 63:4167-4173
Townsley F.M., et al. (1997) Proc. Natl. Acad. Sci. 94:2362-2367
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