Anti-UbcH7
Catalog #: A-640
Product Source:
rabbit polyclonal
UbcH7 mediates the selective degradation of short-lived and abnormal proteins and is highly homologous to UbcH5. UbcH7 interacts with the HECT domain of E6-AP and the RING domain of c-Cbl, and can mediate the multi-ubiquitination of many different types of protein substrates.
Product Information
Stock:
PBS pH 7.4, 20% glycerol
Antigen:
Full-length, highly purified human UbcH7 protein.
Supplied:
Protein A affinity purified rabbit polyclonal antibody.
Use & Storage
Storage:
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Specificity:
Recommended dilution range for Western blot analysis is 1:100 to 1:1000.
Literature
References:
Ardley H.C., et al . (1997) Cytogenet. Cell. Genet . 79 :188-192Biochem . (1997) 36 :1621-1627et al . (1999) Science 286 :1321-1326et al . (1996) J. Biol. Chem . 271 : 2795-2800et al . (1999) J. Biol. Chem . 241 : 30963-30968et al . (1998) J. Biol. Chem . 273 :12148-12154 et al . (2000) Cell 102 :533-539
