A-640

Material Data Sheet

UbcH7/UBE2L3

Price: $159.00
Catalog #: A-640

UbcH7/UBE2L3

Price: 
$159
Quantity: 
200 µL
UbcH7 mediates the selective degradation of short-lived and abnormal proteins and is highly homologous to UbcH5. UbcH7 interacts with the HECT domain of E6-AP and the RING domain of c-Cbl, and can mediate the multi-ubiquitination of many different types of protein substrates.

Product Information

Stock: 
PBS pH 7.4, 20% glycerol
Antigen: 
Full-length, highly purified human UbcH7 protein.
Supplied: 
Protein A affinity purified rabbit polyclonal antibody.

Use & Storage

Use: 

Recommended dilution range for Western blot analysis is 1:100 to 1:1000.

Storage: 

Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.

Literature

References: 

Ardley H.C., et al. (1997) Cytogenet. Cell. Genet. 79:188-192
Cook, W.J. (1997) Biochem. (1997) 36:1621-1627
Huang L., et al. (1999) Science 286:1321-1326
Nuber U., et al. (1996) J. Biol. Chem. 271: 2795-2800
Moynihan T.P., et al. (1999) J. Biol. Chem. 241: 30963-30968
Schwarz S.E., et al. (1998) J. Biol. Chem. 273:12148-12154
Zheng N., et al. (2000) Cell 102:533-539