A-610

Material Data Sheet

UbcH3/Cdc34 Polyclonal Ab

Price: $150.00
Catalog #: A-610

UbcH3/Cdc34 Polyclonal Ab

Price: 
$150
Quantity: 
200 μl
Data Sheet: 
application/pdf iconA-610_antiH3.pdf
Stock: 

PBS pH 7.4, 20% glycerol.

Antigen: 
Full-length, highly purified human UbcH3 protein.
Supplied: 

Protein A affinity purified rabbit polyclonal antibody.

UbcH3 plays an essential role in the progression of cells from the G1 to S phase of the cell division cycle. One pathway (requiring Cdc34) initiates DNA replication by degrading a CDK (cyclin-dependent kinase) inhibitor. The second pathway, involves the anaphase-promoting complex (APC) which initiates chromosome egregation and exit from mitosis by degrading anaphase inhibitors and mitotic cyclins.
Storage: 
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Specificity: 
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.</p>

Literature

References: 

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Seol J.H., et al. (1999) Gene. Dev. 13:1614-1626
Varelas X., et al. (2003) Mol. Cell. Biol. 23:5388-5400