A-605

Material Data Sheet

UbcH2/UBE2H Polyclonal Ab

Price: $150.00

Catalog #: A-605

UbcH2/UBE2H Polyclonal Ab

Price:

$150

Quantity:

200 μl

Data Sheet:

A-605_antiH2.pdf

Stock:

PBS pH 7.4, 20% glycerol.

Antigen:

Full-length, highly purified human UbcH2 protein

Supplied:

Protein A affinity purified rabbit polyclonal antibody.

The UbcH2 enzyme encodes for the human homolog of the yeast Ubc8. UbcH2 can conjugate ubiquitin to histone H2A in an E3-independent manner in vitro, and is essential for the multi-ubiquitination and degradation of N-end rule substrates. Additionally, UbcH2 may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Storage:

Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.

Specificity:

Recommended dilution range for Western blot analysis is 1:100 to 1:1000.</p>

Literature

References:

Baboshina O.V., et al. (2001) J. Biol. Chem. 276:39428-39437
Dohmen J.R., et al. (1991) Proc. Natl. Acad. Sci. 88:7351-7355
Kaiser P., et al. (1995) FEBS. Lett. 377:193-196
Hobler S.C., et al. (1999) Am. J. Physiol. 276:468-473
Wing S.S., et al. (1992) J. Biol. Chem. 267:6495-6501