A-420

Material Data Sheet

Anti-HSP60/CPN60

Price: $159.00
Catalog #: A-420

Anti-HSP60/CPN60

Price: 
$159
Quantity: 
50 µg
Data Sheet: 

Heat shock proteins (HSPs) are a family of highly conserved stress response proteins. Heat shock proteins function primarily as molecular chaperones by facilitating the folding of other cellular proteins, preventing protein aggregation or targeting improperly folded proteins to specific degradative pathways. HSPs are typically expressed at low levels under normal physiological conditions but are dramatically up-regulated in response to cellular stress. Heat Shock Protein 60 (HSP60), also known as Chaperonin 60 (CPN60), is a mitochondrial matrix protein belonging to a highly conserved family of molecular chaperone and stress response proteins. HSP60 plays a role in stabilizing and refolding proteins in response to heat shock or other cellular stress.

Product Information

Stock: 
0.5 mg/mL in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide
Antigen: 
Purified, recombinant human HSP60, Accession Number P10809.

Use & Storage

Use: 

Recommended concentration for Western blot analysis is 0.2 µg/ml.  Recommended concentration for Immunocytochemistry is 8-25μg/mL.

Detects human, mouse, and rat HSP60.

Storage: 

Store at -20°C.

Literature

References: 

Gotoh T., et al. (2002) J. Biol. Chem. 277:12343-50.