A-410

Material Data Sheet

Anti-HSP40/DNAJB1

Price: $159.00
Catalog #: A-410

Anti-HSP40/DNAJB1

Price: 
$159
Quantity: 
50 µg
Data Sheet: 

Heat shock protein 40 kDa (HSP40) is the human homologue of the bacterial DnaJ heat shock protein.  HSP40, also known as HSPF1 and DNAJ Homolog subfamily B member 1 (DNAJB1), is a 340 amino acid, 40 kDa member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. HSP40 is a stress inducible chaperone that co-localizes with HSP70 and can bind unfolded proteins and prevent protein denaturation and aggregation. The conserved amino terminal J domain can interact with HSP70 and stimulate its ATPase activity.

Product Information

Stock: 
0.5 mg/mL in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide
Antigen: 
Purified, recombinant human HSP40 protein, Accession Number P25685

Use & Storage

Use: 

Recommended concentration for Western blot analysis is 0.5 μg/mL.  Detects human, mouse and rat HSP40.

Storage: 

Store at -20°C. 

Literature

References: 

Chien V., et. al.  (2010) Biochem. J.   432: 113-121

Hinault M.P., et. al. (2010)  J Biol. Chem.   285: 38173-38182

Minami Y., et. al.  (1996)  J Biol. Chem.   271:  19617-19624

Qiu X.B., et. al. (2006) Cell Mol. Life. Sci.   63:  2560-2570