1418

Material Data Sheet

Resveratrol

Price: $105.00
Catalog #: 1418

Resveratrol

Price: 
$99
Quantity: 
100 mg
Data Sheet: 

Product Information

MW: 
228.25
Purity: 
>98%
Solubility: 
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Activity: 

A phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 μM) and displays mixed agonist/antagonist actions at ERα and ERβ estrogen receptors. Converted into the anticancer agent piceatannol (Cat. No. 1554) by cytochrome P450 1B1.

Storage: 
Desiccate at +4°C

Literature

References: 

Kimura et al (1985) Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim.Biophys.Acta 834 275. PMID: 3922423.

Chun et al (1999) Resveratrol is a selective human cytochrome P450 1A1 inhibitor. Biochem.Biophys.Res.Commun.262 20. PMID: 10448061.

Bowers et al (2000) Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β. Endocrinology 141 3657. PMID: 11014220.

Fremont (2000) Biological effects of resveratrol. Life Sci. 66 663. PMID: 10680575.

Baur and Sinclair (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat.Rev.Drug Discov. 5 493. PMID: 16732220.