Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


Bacik, J., et al. (2010) “Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME.” J. Biol. Chem. 285: 20273 - 20280.

PubMed ID: 20368332 | Product(s) Referenced: anti-UFM1 primary rabbit polyclonal antibody

Kavazis, A. N., et al. (2010) “Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72.” Am. J. Physiol. Heart Circ. Physiol. 299: H1515-H1524.

PubMed ID: 20833957 | Product(s) Referenced: ubiquitin-protein conjugates

Tang, W., et al. (2010) “Emi2-mediated Inhibition of E2-substrate Ubiquitin Transfer by the Anaphase-promoting Complex/Cyclosome through a D-Box–independent Mechanism.” Mol. Biol. Cell 21: 2589 - 2597.

PubMed ID: 20534816 | Product(s) Referenced: anti UbcH10

Kumar, B., et al. (2010) “The C Terminus of Rpt3, an ATPase Subunit of PA700 (19 S) Regulatory Complex, Is Essential for 26 S Proteasome Assembly but Not for Activation.” J. Biol. Chem. 285: 39523-39535.

PubMed ID: 20937828 | Product(s) Referenced: anti-Rpt3

Liang, J., et al. (2010) “MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-B signaling.” J. Exp. Med. 207: 2959-2973.

PubMed ID: 21115689 | Product(s) Referenced: anti-ubiquitin

Van Ree, J., et al. (2010) “Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.” J. Cell Biol. 188: 83 - 100.

PubMed ID: 20065091 | Product(s) Referenced: rabbit anti-UbcH10

Vina-Vilaseca, A. and Sorkin, A. (2010) “Lysine 63-linked Polyubiquitination of the Dopamine Transporter Requires WW3 and WW4 Domains of Nedd4-2 and UBE2D Ubiquitin-conjugating Enzymes.” J. Biol. Chem. 285: 7645 - 7656.

PubMed ID: 20051513 | Product(s) Referenced: Affinity purified rabbit polyclonal anti-UBE2L3

Bianchi, G., et al. (2009) "The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition." Blood 113: 3040-3049.

PubMed ID: 19164601 | Product(s) Referenced: rabbit anti-X, rabbit anti-Y

Chen, A., et al. (2009) “The HECT-Type E3 Ubiquitin Ligase AIP2 Inhibits Activation-Induced T-Cell Death by Catalyzing EGR2 Ubiquitination.” Mol. Cell. Biol. 29: 5348 - 5356.

PubMed ID: 19651900 | Product(s) Referenced: anti-ubiquitin antibody

Kadara, H., et al. (2009) “Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System.” Cancer Prevention Research 2: 702 - 711.

PubMed ID: 19638491 | Product(s) Referenced: purified primary rabbit polyclonal anti-human UBE2C/UBCH10 antibody

Williamson, A., et al. (2009) “Identification of a physiological E2 module for the human anaphase-promoting complex.” PNAS 106: 18213 - 18218.

PubMed ID: 19822757 | Product(s) Referenced: anti-UbcH10

Bruce, S.R., et al (2009) "Respiratory Syncytial Virus (RSV) Infection Alters Surfactant Protein-A (SP-A) Expression in Human Pulmonary Epithelial Cells by Reducing Translation Efficiency." Am J Physiol Lung Cell Mol Physiol: 90507.2008.

PubMed ID: 19525387 | Product(s) Referenced: rabbit anti-human ubiquitin antibody

Meyer-Schaller, N., et al. (2009) “The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.” PNAS 106: 12365 - 12370.

PubMed ID: 19617556 | Product(s) Referenced: hUbc12 / A-655

Whitcomb, E.A., et al. (2009) "Novel Control of S Phase of the Cell Cycle by Ubiquitin-conjugating Enzyme H7." Mol. Biol. Cell 20(1): 1-9.

PubMed ID: 18946090 | Product(s) Referenced: anti-Ubc2, anti-UbcH10, anti-UbcH7 polyclonal

Page, E.L., et al. (2008) "Hypoxia-inducible Factor- [alpha] Stabilization in Non-hypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion." Mol. Biol. Cell 19: 86-94.

PubMed ID: 17942596 | Product(s) Referenced: Anti-ubiquitin

Liu, J., et al. (2008) "A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome." Am. J. Physiol. Heart.Circ. Physiol. 295(6): H2541-H2550.

PubMed ID: 18978187 | Product(s) Referenced: anti-COOH-terminal of heat shock protein cognate 70-interacting protein

Walker A., et al. (2008) "UbcH10 has a rate-limiting role in G1 phase but might not act in the spindle checkpoint or as part of an autonomous oscillator." J. Cell. Sci. 121: 2319-2326.

PubMed ID: 18559889 | Product(s) Referenced: anti-UbcH10

Worby, C.A., et al. (2008) "Malin Decreases Glycogen Accumulation by Promoting the Degradation of Protein Targeting to Glycogen (PTG)." J. Biol. Chem. 283: 4069-76.

PubMed ID: 18070875 | Product(s) Referenced: avidin-HRP

Yamano T., et al. (2008) "[alpha]-Synuclein Protofibrils Inhibit 26 S Proteasome-mediated Protein Degradation: UNDERSTANDING THE CYTOTOXICITY OF PROTEIN PROTOFIBRILS IN NEURODEGENERATIVE DISEASE PATHOGENESIS." J. Biol. Chem. 283(29): 20288-20298.

PubMed ID: 18502751 | Product(s) Referenced: anti-UbcH10 polyclonal

Hrecka, K., M. Gierszewska, et al. (2007). "Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle." PNAS 104(28): 11778-11783.

PubMed ID: 17609381 | Product(s) Referenced: anti-NEDD8

Prager, K., et al. (2007) "A Structural Switch of Presenilin 1 by Glycogen Synthase Kinase 3[beta]-mediated Phosphorylation Regulates the Interaction with [beta]-Catenin and Its Nuclear Signaling." J. Biol. Chem. 282(19): 14083-14093.

PubMed ID: 17360711 | Product(s) Referenced: anti-ubiquitin

Chen, Y., et al. (2006). "Proteasome-dependent down-regulation of activated Stat5A in the nucleus." Blood 108(2): 566-574.

PubMed ID: 16569768 | Product(s) Referenced: anti–human Ubc5 polyclonal

van Waardenburg, R. C. A. M., et al. (2006). "Distinct Functional Domains of Ubc9 Dictate Cell Survival and Resistance to Genotoxic Stress." Mol. Cell. Biol. 26(13): 4958-4969.

PubMed ID: 16782883 | Product(s) Referenced: anti-Ubc9 (A-645)

Yuasa, M. S., et al. (2006). "A human DNA polymerase-εcomplex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest." Genes Cells 11(7): 731-744.

PubMed ID: 16824193 | Product(s) Referenced: rabbit polyclonal anti-Rad6 (Ubch2)

Havens, C. G., et al. (2006) "Regulation of Late G1/S Phase Transition and APCCdh1 by Reactive Oxygen Species." Mol. Cell. Biol. 26(12): 4701-4711.

PubMed ID: 16738333 | Product(s) Referenced: anti-UbcH10


Havens, C. G., et al. (2006) "Regulation of Late G1/S Phase Transition and APCCdh1 by Reactive Oxygen Species." Mol. Cell. Biol. 26(12): 4701-4711.

PubMed ID: 16738333

Deconjugating Enzymes

PubMed ID: 24130053 | Product(s) Referenced: purified USP5

Deubiquitinating Enzymes

PubMed ID: 23536702 | Product(s) Referenced: His6-USP2CD (UBP41 catalytic domain)
PubMed ID: 23375434 | Product(s) Referenced: human recombinant isopeptidase T
PubMed ID: 23869922 | Product(s) Referenced: isopeptidase T
PubMed ID: 23930225 | Product(s) Referenced: ATG4B

Issaenko, O.A. and Amerik, A.Y. (2012) "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes." Cell cycle (Georgetown, Tex.) 11(9).

PubMed ID: 22510564 | Product(s) Referenced: purified human DUB, purified USP5

Reverdy, C. et al. (2012) "Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme." Chem. Biol. 19(4): 467–477.

PubMed ID: 22520753 | Product(s) Referenced: UCH-L1, UCH-L3, USP2, USP20, USP5, E-340, E-325, E-506, E-344, E-322

Shi, T. et al. (2012) "Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen." BMC chemical biology 12(1): 4.

PubMed ID: 22584113 | Product(s) Referenced: A20 catalytic domain

Zang, Y. et al. (2012) "Rice UBC13, a candidate housekeeping gene, is required for K63-linked polyubiquitination and tolerance to DNA damage." Rice 5(1): 24.

PubMed ID: 10.1186/1939-8433-5-24 | Product(s) Referenced: E1 enzyme, K48R ubiquitin, K63R ubiquitin, reaction buffer, Ub, Ubc13, Uev1A, ubiquitin-AMC, nonbiotinylated USP2 catalytic domain, USP10, USP47, USP5, USP7

Cotto-Rios, X.M. et al. (2012) "Deubiquitinases as a signaling target of oxidative stress." Cell Rep 2(6): 1475–1484.

PubMed ID: 23219552 | Product(s) Referenced: UbVME, recombinant ubiquitin chain K48-linked, UCH-L1, SENP1-CD, STAM, recombinant ubiquitin chain K63-linked, SUMO1-vs, USP7, AMSH,

Capodagli, G., et al. (2011) “Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin.” Journal of Virology, 85: 3621-3630.

PubMed ID: 21228232 | Product(s) Referenced: Ub-AMC

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” 

PubMed ID: 21343341 | Product(s) Referenced: ubiquitin aldehyde

James, T., et al. (2011) “Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.” PNAS, 108: 2222-2227.

PubMed ID: 21245344 | Product(s) Referenced: ISG15–AMC

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

PubMed ID: 21795702 | Product(s) Referenced: Wild-type ubiquitin

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

PubMed ID: 21163868 | Product(s) Referenced: ubiquitin aldehyde