Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


Yang Z., et al. (2008) "Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication." J. Virol. 82: 3590-603.

Product(s) Referenced: human flag-ubiquitin

Yasukawa, T., et al. (2008) "Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.” The EMBO Journal 27(24): 3256–3266.

PubMed ID: 19037258 | Product(s) Referenced: ubiquitin aldehyde

Zhang, Z. and Zhang, R. (2008) "Proteasome activator PA28[gamma] regulates p53 by enhancing its MDM2-mediated degradation.” The EMBO journal 27(6): 852–864.

PubMed ID: 18309296 | Product(s) Referenced: Myc-Ubiquitin

Barriere, H., et al. (2007). "Plasticity of Poly-Ubiquitin Recognition as Lysosomal Targeting Signals by the Endosomal Sorting Machinery." Mol. Biol. Cell. 18(10) :3952-3965.

PubMed ID: 17686993 | Product(s) Referenced: K63-linked poly-Ub chain

Bish, R. A. and M. P. Myers (2007). "Werner Helicase-interacting Protein 1 Binds Poly-ubiquitin via Its Zinc Finger Domain." J. Biol. Chem. 282(32): 23184-23193.

PubMed ID: 17550899 | Product(s) Referenced: ubiquitin (monoubiquitin or Lys-48- or Lys-63-linked polyubiquitin chains 1–7)

Braun, M. A., et al. (2007). "Identification of Rkr1, a Nuclear RING Domain Protein with Functional Connections to Chromatin Modification in Saccharomyces cerevisiae." Mol. Cell. Biol. 27(8): 2800-2811.

PubMed ID: 17283062 | Product(s) Referenced: ubiquitin (human recombinant)

Butler, M. P., et al. (2007). "Kinase active IRAKs promote polyubiquitination and degradation of the Pellino family: Direct evidence for Pellino proteins being E3 ubiquitin ligases." J. Biol. Chem. 282:29729-29737.

PubMed ID: 17675297 | Product(s) Referenced: K48R ubiquitin

Chen, Z., Y. Wang, et al. (2007). "Proteolytic Processing and Deubiquitinating Activity of Papain-Like Proteases of Human Coronavirus NL63." J. Virol. 81(11): 6007-6018.

PubMed ID: 17392370 | Product(s) Referenced: K48-Ub6

Ferdous, A., et al. (2007). "The role of the proteasomal ATPases and activator mono-ubiquitylation in regulating Gal4 binding to promoters." Genes & Dev. 21(1): 112-123.

PubMed ID: 17167105 | Product(s) Referenced: His6-tagged ubiquitin with a Lys 48-to-arginine (K48R) mutation

Ghaboosi, N. and R. J. Deshaies (2007). "A Conditional Yeast E1 Mutant Blocks the Ubiquitin-Proteasome Pathway and Reveals a Role for Ubiquitin Conjugates in Targeting Rad23 to the Proteasome." Mol. Biol. Cell 18(5): 1953-1963.

PubMed ID: 17360968 | Product(s) Referenced: tetra-ubiquitin (Ub4)

Hong, K. U., et al. (2007). "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis." Mol. Cell. Biol. 27(10): 3667-3681.

PubMed ID: 17339342 | Product(s) Referenced: human ubiquitin

Joch, M., et al. (2007). "Parkin-mediated Mono-ubiquitination of the PDZ Protein PICK1 Regulates the Activity of Acid-sensing Ion Channels." Mol. Biol. Cell 18(8): 3105-3118.

PubMed ID: 17553932 | Product(s) Referenced: Ub

Kamynina, E., et al. (2007). "Regulation of Proto-Oncogenic Dbl by Chaperone-Controlled, Ubiquitin-Mediated Degradation." Mol. Cell. Biol. 27(5): 1809-1822.

PubMed ID: 17178836 | Product(s) Referenced: Myc-ubiquitin

Kerns, S. L., et al. (2007). "Geminin Prevents Re-replication during Xenopus Development." J. Biol. Chem. 282(8): 5514-5521.

PubMed ID: 17179155 | Product(s) Referenced: methylated ubiquitin

Kong, H. J., et al. (2007). "Cutting Edge: Autoantigen Ro52 Is an Interferon Inducible E3 Ligase That Ubiquitinates IRF-8 and Enhances Cytokine Expression in Macrophages." J. Immunol. 179(1): 26-30.

PubMed ID: 17579016 | Product(s) Referenced: purified ubiquitin

Lamothe, B., et al. (2007). "Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation." J. Biol. Chem. 282(6):Determinant of I 4102-4112.

PubMed ID: 17135271 | Product(s) Referenced: WT ubiquitin, His-Ub, K48R ubiquitin, K63R ubiquitin, KO ubiquitin, Lys-48 only ubiquitin, Lys-63 only ubiquitin

Liu, Y., et al. (2007). "Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate." Canc. Res. 67(6): 2685-2692.

PubMed ID: 17363589 | Product(s) Referenced: methyl ubiquitin

Lu, Z., et al. (2007). "Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction." J. Cell Biol. 177(6): 1077-1081.

PubMed ID: 17576800 | Product(s) Referenced: ubiquitin

Miller, S. L. H., et al. (2007). "Ubiquitin-interacting Motifs Inhibit Aggregation of PolyQ-expanded Huntingtin." J. Biol. Chem. 282(13): 10096-10103.

PubMed ID: 17276991 | Product(s) Referenced: Lys63-linked polyubiquitin chains ranging from 2-7 ubiquitins

Olzmann, J.A., et al. (2007) "Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6." J. Cell Biol. 178(6): 1025-1038.

PubMed ID: 17846173 | Product(s) Referenced: ubiquitin, ubiquitin mutants

Petroski, M. D., et al. (2007). "Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme." J. Biol. Chem. 282:29729-29737.

PubMed ID: 17709375 | Product(s) Referenced: K0 ubiquitin, K63R ubiquitin, Lys63 only ubiquitin, Ubiquitin

Pick, E., et al. (2007). "Mammalian DET1 Regulates Cul4A Activity and Forms Stable Complexes with E2 Ubiquitin-Conjugating Enzymes.” Mol. Cell. Biol. 27(13): 4708-4719.

PubMed ID: 17452440 | Product(s) Referenced: N-terminal biotinylated ubiquitin

Row, P. E., H. Liu, et al. (2007). "The MIT domain of UBPY constitutes a CHMP binding and endosomal localisation signal required for efficient EGF receptor degradation." J. Biol. Chem.: 282:30929-30937.

PubMed ID: 17711858 | Product(s) Referenced: wild-type Lys-63-linked tetraubiquitin chains

Rytkonen, A., et al. (2007) "SseL, a Salmonella deubiquitinase required for macrophage killing and virulence4." PNAS 104(9): 3502-3507.

Product(s) Referenced: ubiquitin-AMC

Skaar, J. R., et al. (2007). "PARC and CUL7 Form Atypical Cullin RING Ligase Complexes.” Cancer Res. 67(5): 2006-2014.

PubMed ID: 17332328 | Product(s) Referenced: GST-ubiquitin