Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


Schwickart, M., et al. (2009) "Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.” Nature 463(7277): 103–107.

PubMed ID: 20023629 | Product(s) Referenced: Lys 48-linked polyubiquitin, Lys 63-linked polyubiquitin

Shanks. J., et al. (2009) "Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages." Infect. Immun. 77 (4): 1636-1648.

PubMed ID: 19168747 | Product(s) Referenced: K48-linked Ub dimer, K63-linked Ub dimer

Shao, G., et al. (2009) "MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks." Genes & Dev. 23: 740-754.

PubMed ID: 19261746 | Product(s) Referenced: K63-linked hexa-ubiquitin

Shenoy, S.K., et al. (2009) "b-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2." PNAS 106: 6650-6655.

PubMed ID: 19363159 | Product(s) Referenced: Polyubiquitin chain with Lys-48 linkage, Polyubiquitin chain with Lys-63 linkage

Siepe, D. and Jentsch, S. (2009) "Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation.” Nature Cell Biology 11(8): 967–972.

PubMed ID: 19597489 | Product(s) Referenced: recombinant ubiquitin

Singh, R.K., et al. (2009) "Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis.” Nature cell biology 11(8): 925–933.

PubMed ID: 19578373 | Product(s) Referenced: recombinant 6-His-tagged human ubiquitin

Stanisic, V., et al (2009) "OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER)a and Affects ERa Transcriptional Activity." J. Biol. Chem. 284: 16135-16145.

PubMed ID: 19383985 | Product(s) Referenced: Flag-ubiquitin (U-120), Ubiquitin-AFC

Stewart, G.S., et al. (2009) "The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage.” Cell 136(3): 420–434.

PubMed ID: 19203578 | Product(s) Referenced: ubiquitin

Todi, S.V., et al. (2009) "Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3.” The EMBO journal 28(4): 372–382.

PubMed ID: 19153604 | Product(s) Referenced: Ub chains, Ub3-7 chains

Uchiki T., et al. (2009) "The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition." J. Biol. Chem. 284: 12622-12632.

PubMed ID: 19240029 | Product(s) Referenced: Ub1-7 chains

Wang, X., et al. (2009) “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

PubMed ID: 19951915 | Product(s) Referenced: HA-Ub, Ub-Al

Wawrzynow, B., et al. (2009) "A Function for the RING Finger Domain in the Allosteric Control of MDM2 Conformation and Activity." J. Biol. Chem. 284: 11517-11530.

PubMed ID: 19188367 | Product(s) Referenced: Ubiquitin(U-100)

Amsel A.D., et al. (2008). "Regulation of the pro-apoptotic factor Bax by Ku70-dependent deubiquitylation." PNAS 105: 5117-22.

PubMed ID: 15659549 | Product(s) Referenced: hexaubiquitin, tetraubiquitin

Archer C.T., et al. (2008). "Physical and Functional Interactions of Monoubiquitylated Transactivators with the Proteasome." J. Biol. Chem. 283(31): 21789-21798.

PubMed ID: 18515799 | Product(s) Referenced: biotinylated ubiquitin

Balastik, M., et al. (2008). "Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration." PNAS 105 (33): 12016-12021.

PubMed ID: 18687884 | Product(s) Referenced: ubiquitin aldehyde

Bazirgan O.A and Hampton R.Y. 2008. "Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo." J. Biol. Chem: 283(19):12797-810.

PubMed ID: 18321851 | Product(s) Referenced: Mutant varieties of ubiquitin

Chitalia, V.C., et al. (2008) "Jade-1 inhibits Wnt signalling by ubiquitylating [beta]-catenin and mediates Wnt pathway inhibition by pVHL.” Nature cell biology 10(10): 1208–1216.

PubMed ID: 18806787 | Product(s) Referenced: Myc-tagged ubiquitin

Choi, D.W., et al. (2008) "Ubiquitination and Degradation of Homeodomain-interacting Protein Kinase 2 by WD40 Repeat/SOCS Box Protein WSB-1." J. Biol. Chem. 283: 4682-4689.

PubMed ID: 18093972 | Product(s) Referenced: ubiquitin aldehyde

Conze, D.B., et al. (2008) “Lys63-Linked Poly-ubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation.” Mol. Cell. Biol. 28: 3538-47.

PubMed ID: 18347055 | Product(s) Referenced: K63-only mutant ubiquitin

Daulny, A., et al. (2008) "Modulation of RNA polymerase II subunit composition by ubiquitylation." PNAS 105(50): 19649-19654.

PubMed ID: 19064926 | Product(s) Referenced: GST- ubiquitin

Durfee L.A,. et al (2008). "The Basis for Selective E1-E2 Interactions in the ISG15 Conjugation System." J. Biol. Chem. 283(35):23895-23902.

PubMed ID: 18583345 | Product(s) Referenced: Ube1L

Heuzé, M.L., et al. (2008) "ASB2 targets filamins A and B to proteasomal degradation." Blood 112(13): 5130-5140.

PubMed ID: 18799729 | Product(s) Referenced: ubiquitin

Karagianni, P., et al. (2008) "ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation." Mol. Cell. Biol. 28: 705-17.

PubMed ID: 17967883 | Product(s) Referenced: ubiquitin

Kawahara, K., et al. (2008) [alpha]-Synuclein Aggregates Interfere with Parkin Solubility and Distribution: ROLE "IN THE PATHOGENESIS OF PARKINSON DISEASE." J. Biol. Chem. 283: 6979-6987.

Product(s) Referenced: ubiquitin

Koh, M.Y., et al. (2008) "Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1, Leading to Its Oxygen-Independent Degradation." Mol. Cell. Biol. 28 (23):7081-7095.

PubMed ID: 18838541 | Product(s) Referenced: human recombinant ubiquitin