Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


Simonin, A. and Fuster, D. (2010) “Nedd4-1 and [beta]-Arrestin-1 Are Key Regulators of Na+/H+ Exchanger 1 Ubiquitylation, Endocytosis, and Function.” J. Biol. Chem. 285: 38293-38303.

PubMed ID: 20855896 | Product(s) Referenced: Lys63-linked polyubiquitin ladder

Singh, M., et al. (2010) "Extracellular ubiquitin inhibits [beta]-AR-stimulated apoptosis in cardiac myocytes: role of GSK-3[beta] and mitochondrial pathways." Cardiovasc Res. 86: 20 - 28.

PubMed ID: 20015977 | Product(s) Referenced: biotinylated Ub (BiotUb), methylated Ub (MeUb)

Song, E.J., et al. (2010) “The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.” Genes & Dev. 24: 1434 - 1447.

PubMed ID: 20595234 | Product(s) Referenced: recombinant Lys48-linked chains, recombinant Lys63-linked chains, recombinant ubiquitin, ubiquitin mutants

Song, I. Y., et al. (2010) “Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway.” J. Biol. Chem. 285: 31525-31536.

PubMed ID: 20675655 | Product(s) Referenced: ubiquitin

Takedachi, A., et al. (2010) "DDB2 Complex-Mediated Ubiquitylation around DNA Damage Is Oppositely Regulated by XPC and Ku and Contributes to the Recruitment of XPA." Mol. Cell. Biol. 30: 2708 - 2723.

PubMed ID: 20368362 | Product(s) Referenced: 6×His-ubiquitin

Walters, M.S., et al. (2010) “The RING Finger Domain of Varicella-Zoster Virus ORF61p Has E3 Ubiquitin Ligase Activity That Is Essential for Efficient Autoubiquitination and Dispersion of Sp100-Containing Nuclear Bodies.” J. Virol. 84: 6861 - 6865.

PubMed ID: 20392849 | Product(s) Referenced: ubiquitin

Wang A.M., et al. (2010) "Inhibition of Hsp70 by Methylene Blue Affects Signaling Protein Function and Ubiquitination and Modulates Polyglutamine Protein Degradation." J. Biol. Chem. 285: 15714 - 15723.

PubMed ID: 20348093 | Product(s) Referenced: GST-tagged ubiquitin, poly-Ub(3-7)-K48-linked, poly-Ub(3-7)-K63-linked

Wang, H., et al. (2010). "Activating Transcription Factor 3 Activates p53 by Preventing E6-associated Protein from Binding to E6." J. Biol. Chem. 285: 13201 - 13210.

PubMed ID: 20167600 | Product(s) Referenced: methylated ubiquitin

Wang, X.H., et al. (2010). “Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity.” J. Biol. Chem. 285: 21249 - 21257.

PubMed ID: 20424172 | Product(s) Referenced: ubiquitin-aldehyde (Ubal)

Wojdyla, J. A., et al. (2010) “Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates.” J. Virol. 84: 10063-10073.

PubMed ID: 20668092 | Product(s) Referenced: Lys48- and Lys63-linked polyubiquitin chains

Xu, G., et al. (2010) “Ubiquitin-specific Peptidase 21 Inhibits Tumor Necrosis Factor -induced Nuclear Factor B Activation via Binding to and Deubiquitinating Receptor-interacting Protein 1.” J. Biol. Chem. 285: 969 - 978.

PubMed ID: 19910467 | Product(s) Referenced: Human recombinant Lys48-linked polyubiquitin wild type chains, Human recombinant Lys63-linked polyubiquitin wild type chains

Yang, Y., et al. (2010) “E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNF-induced JNK activation.” PNAS 107: 13444 - 13449.

PubMed ID: 20624960 | Product(s) Referenced: HA-ubiquitin, ubiquitin K480, ubiquitin K630

Yu, H., et al. (2010) “The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and is a Critical Regulator of Gene Expression.” Mol. Cell. Biol. 10.1128/MCB.00396-10.

PubMed ID: 20805357 | Product(s) Referenced: Ub-AMC

Zeng, W., et al. (2010) "Reconstitution of the RIG-I Pathway Reveals a Pivotal Role of Unanchored Polyubiquitin Chains in Innate Immunity.” Cell 141(2): 315–330.

PubMed ID: 20403326 | Product(s) Referenced: synthetic K63-Ub6

Barajas, D., et al. (2009). “The Nedd4-Type Rsp5p Ubiquitin Ligase Inhibits Tombusvirus Replication by Regulating Degradation of the p92 Replication Protein and Decreasing the Activity of the Tombusvirus Replicase.” J. Virol. 83: 11751 - 11764.

PubMed ID: 19759160 | Product(s) Referenced: purified six-His-tagged human ubiquitin

Bekker-Jensen, S., et al. (2009) "HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.” Nature cell biology 12(1): 80–86.

PubMed ID: 20023648 | Product(s) Referenced: Flag–ubiquitin

Bernal-Bayard, J. and Ramos-Morales, F. (2009) “Salmonella Type III Secretion Effector SlrP Is an E3 Ubiquitin Ligase for Mammalian Thioredoxin.” J. Biol. Chem. 284: 27587 - 27595.

PubMed ID: 19690162 | Product(s) Referenced: HA-tagged ubiquitin

Berthouze, M., et al. (2009) "The deubiquitinases USP33 and USP20 coordinate [beta]2 adrenergic receptor recycling and resensitization.” The EMBO journal 28(12): 1684–1696.

PubMed ID: 19424180 | Product(s) Referenced: Polyubiquitin chains (K48-linked), Polyubiquitin chains (K63-linked)

Burnett, B.G., et al. (2009) "Regulation of SMN Protein Stability." Mol. Cell. Biol. 29: 1107-1115.

PubMed ID: 19103745 | Product(s) Referenced: ubiquitin aldehyde

Burns, M., et al. (2009) "Parkin promotes intracellular A[beta]1–42 clearance." Hum. Mol. Genet. 18: 3206 - 3216.

PubMed ID: 19483198 | Product(s) Referenced: recombinant human ubiquitin

Cheng, Q., et al. (2009) "ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.” The EMBO journal 28(24): 3857–3867.

PubMed ID: 19816404 | Product(s) Referenced: K0-ubiquitin

Cohn, M.A., et al. (2009) "UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes." J. Biol. Chem. 284 (8): 5343-5351.

PubMed ID: 19075014 | Product(s) Referenced: ubiquitin-AMC (ubiquitin-7-amido-4-methylcoumarin)

Colland, F., et al. (2009) “Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.” Mol. Cancer Ther. 8: 2286 - 2295.

PubMed ID: 19671755 | Product(s) Referenced: SUMO-AMC

Cooper, E.M., et al. (2009) "K63-specific deubuiquitination by two JAMM/MPN+ complexes:BRISC-associated Brcc-36 and proteasomal Poh1." EMBO J. 28(6) 621-631.

PubMed ID: 19214193 | Product(s) Referenced: Mixed-linkage K48–K63–K48 tetraUb

Corcoran, C., et al. (2009) “Identification and Characterization of Two Novel Isoforms of Pirh2 Ubiquitin Ligase That Negatively Regulate p53 Independent of RING Finger Domains.” J. Biol. Chem. 284: 21955 – 21970.

PubMed ID: 19483087 | Product(s) Referenced: 100 ng of E1, 200 ng of E2, 2 μg of ubiquitin (Boston Biochem, Cambridge, MA)