Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


Bernstein, S.H. et al. (2012) "The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives." Blood 119(14): 3321–3329.

PubMed ID: 22323447 | Product(s) Referenced: 20S proteasome

Gustin, J.K. et al. (2012) "Ubiquitination of BST-2 Protein by HIV-1 Vpu Protein Does Not Require Lysine, Serine, or Threonine Residues within the BST-2 Cytoplasmic Domain." J. Biol. Chem. 287(18): 14837–14850.

PubMed ID: 22383521 | Product(s) Referenced: MG132

Issaenko, O.A. and Amerik, A.Y. (2012) "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes." Cell cycle (Georgetown, Tex.) 11(9).

PubMed ID: 22510564 | Product(s) Referenced: Ubiquitin aldehyde (Ubal), 20S Human proteasome

Long, M.J.C. et al. (2012) "Inhibitor Mediated Protein Degradation." Chemistry & Biology 19(5): 629–637.

PubMed ID: 22633414 | Product(s) Referenced: immunoproteasome from mouse spleen, Purified 20S proteasome from HeLa, IU1

Thompson, J.W. et al. (2012) "Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5)." J. Biol. Chem. 287(10): 7357–7365.

PubMed ID: 22253436 | Product(s) Referenced: MG132

Tsihlis, N.D. et al. (2012) "Nitric oxide decreases activity and levels of the 11S proteasome activator PA28 in the vasculature." Nitric Oxide 27(1): 50–58.

PubMed ID: 22561112 | Product(s) Referenced: recombinant PA28, Bz-VGR-AMC (trypsin-like), Suc-LLVY-AMC (chymotrypsin-like), Z-LLE-AMC (caspase-like)

Xu, H. et al. (2012) "The CCAAT box-binding transcription factor NF-Y regulates basal expression of human proteasome genes." Biochim. Biophys. Acta 1823(4): 818–825.

PubMed ID: 22285817 | Product(s) Referenced: MG132, Suc-Leu-Leu-Val-Tyr-AMC pep- tide substrate

Zheng, J. et al. (2012) "Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis." J. Neurochem. 121(3): 486–494.

PubMed ID: 22353035 | Product(s) Referenced: immunoproteasome, standard proteasome

Blackburn C, Barrett C, Blank JL, et al. "Optimization of a series of dipeptides with a P3 β-neopentyl asparagine residue as non-covalent inhibitors of the chymotrypsin-like activity of human 20S proteasome." Med. Chem. Commun. 2012 May 30;3(6):710–719. 

PubMed ID: 10.1039/C2MD20060K | Product(s) Referenced: purified human erythrocyte and peripheral blood monocyte 20S proteasomes, recombinant proteasomal activator PA28alpha, Z-LLE-AMC

Gobec, M. et al. (2012) "Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition." PLoS ONE 7(7): e41961.

PubMed ID: 22860040 | Product(s) Referenced: purified human 20S proteasome

Burrows, A.C. et al. (2012) "Skp1-Cul1-F-box Ubiquitin Ligase (SCFβTrCP)-Mediated Destruction of the Ubiquitin-Specific Protease USP37 During G2-phase Promotes Mitotic Entry." J. Biol. Chem.

PubMed ID: 23027877 | Product(s) Referenced: MG132, UbcH10 antibody

Carvalho, A.N. et al. (2012) "Ubiquitin-Proteasome System Impairment and MPTP-Induced Oxidative Stress in the Brain of C57BL/6 Wild-type and GSTP Knockout Mice." Mol. Neurobiol.

PubMed ID: 23129554 | Product(s) Referenced: Z-leucine-leucine-glutamic acid-7-amido-4-methylcoumarin (Z-LLE-AMC), Boc-leucine-arginine-arginine-7-amido-4-methylcoumarin (Boc-LRR-AMC), succcinyl-leucine-leucine-valine-tyro-sine-7-amido-4-methylcoumarin (Suc-LLVY-AMC), isopeptidase inhibitor (Ubiquitin aldehyde [Ubal]), MG132,

Dechavanne, V. et al. (2012) "Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC-MS." Protein Expr. Purif.

PubMed ID: 23147206 | Product(s) Referenced: Rabbit AP-123 polyclonal antibody, anti-beta2-20S human proteasome

Foy, R.L. et al. (2012) "Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1." Hum. Mol. Genet.

PubMed ID: 23001567 | Product(s) Referenced: lactacystin, MG132

Guan, B. et al. (2012) "Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions." Neoplasia 14(10): 986–993.

PubMed ID: 23097632 | Product(s) Referenced: MG132

Held, S.A.E. et al. (2012) "Imatinib mesylate and nilotinib affect MHC-class I presentation by modulating the proteasomal processing of antigenic peptides." Cancer Immunol. Immunother.

PubMed ID: 23184338 | Product(s) Referenced: isolated and purified 20S proteasomes

Henle, A.M. et al. (2012) "Enzymatic Discovery of a HER-2/neu Epitope That Generates Cross-Reactive T Cells." J. Immunol.

PubMed ID: 23180824 | Product(s) Referenced: Suc-LLVY-AMC, synthetic lactacystin, reaction buffer (25 mM HEPES, 0.5 mM EDTA, pH 7.6), immunoproteasome, PA28 activator alpha subunit, purified human 20S proteasome

Lansdell, T.A. et al. (2012) "Non-competitive modulation of the proteasome by imidazoline scaffolds overcome bortezomib resistant and delay MM tumor growth in vivo." ACS Chem. Biol.

PubMed ID: 23198928 | Product(s) Referenced: purified proteasome particles, Suc-LLVY-AMC, Z-ARR-AMC, Z-LLE-AMC

Lu, B. et al. (2012) "Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA(+) Lon Protease." Mol. Cell.

PubMed ID: 23201127 | Product(s) Referenced: 20S proteasome

Xu, X. et al. (2012) "Identification of insulin receptor substrate 1’s degradation determinants for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination." J. Biol. Chem. 287(48):40758-66.

PubMed ID: 23045529 | Product(s) Referenced: E1, MG132

Zhang, Z. et al. (2012 "1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity." J. Biol. Inorg. Chem. 17(8): 1257–1267.

PubMed ID: 23053530 | Product(s) Referenced: purified human 20S proteasome, human ubiquitin activating enzyme E1, UbcH10

Zhao, X. et al. (2012) "Orai1 mediates exacerbated ca(2+) entry in dystrophic skeletal muscle." PLoS ONE 7(11): e49862.

PubMed ID: 23185465 | Product(s) Referenced: lactacystin

Zhu, Y. et al. (2012) "Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols." J. Agric. Food Chem. 60(35): 8624–8631.

PubMed ID: 22897570 | Product(s) Referenced: human 20S proteasome, proteasome activator PA28, Suc-Leu-Leu-Val-Tyr-AMC (Suc-LLVY-AMC)

Ismail, A. et al. (2012) "Proteasome Inhibitory Potential of Commonly Consumed Dietary Ingredients." International Journal of Food and Nutrition Science 1(4): 27–31.

Product(s) Referenced: 20S proteasome purified from rabbit

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

PubMed ID: 21364033 | Product(s) Referenced: MG-132