Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.


He, F., B. J. Fenner, et al. (2006). "White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor via Ubiquitination." J. Virol. 80(8): 3884-3892.

PubMed ID: 16571805 | Product(s) Referenced: MG132

Arias E. E. and Walter J.C. (2005) "Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts." Genes & Dev. 19(1): 114-126.

PubMed ID: 20724660 | Product(s) Referenced: MG132

Dudek E. J., et al. (2005) "Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseases." FASEB J (12): 1707-9.

PubMed ID: 16099947 | Product(s) Referenced: lactacystin-[beta]-lactone

Hata T., et al. (2005) "Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells." Mol. Canc. Ther. 4(10): 1585-1594.

PubMed ID: 16227409 | Product(s) Referenced: clasto-lactacystin [beta]-lactone (Lactacystin)

Koshikawa N. and Takenaga K. (2005) "Hypoxia-Regulated Expression of Attenuated Diphtheria Toxin A Fused with Hypoxia-Inducible Factor-1[alpha]/Oxygen-Dependent Degradation Domain Preferentially Induces Apoptosis of Hypoxic Cells in Solid Tumor." Can. Res. 65.

PubMed ID: 16357173 | Product(s) Referenced: ubiquitin aldehyde

Kus B., et al. (2005) "A High Throughput Screen to Identify Substrates for the Ubiquitin Ligase Rsp5." J. Biol. Chem. 280(33): 29470-29478.

PubMed ID: 15955809 | Product(s) Referenced: MG-132

Lindner H. A., et al. (2005) "The Papain-Like Protease from the Severe Acute Respiratory Syndrome Coronavirus is a Deubiquitinating Enzyme." J. Virol. 79(24): 15199-15208.

PubMed ID: 16306591 | Product(s) Referenced: ubiquitin aldehyde

Lotz C., et al. (2005) "Targeting Positive Regulatory Domain I-Binding Factor 1 and X Box-Binding Protein 1 Transcription Factors by Multiple Myeloma-Reactive CTL." J. Immunol. 175(2): 1301-1309.

PubMed ID: 16002735 | Product(s) Referenced: lactacystin

Maynard M. A., et al. (2005) "Human HIF-3[alpha] 4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma." FASEB J 19(11): 1396-1406.

PubMed ID: 16126907 | Product(s) Referenced: MG-132

Yimlamai T., et al. (2005) "Clenbuterol induces muscle-specific attenuation of atrophy through effects on the ubiquitin-proteasome pathway." J Appl Physiol 99(1): 71-80.

PubMed ID: 15774696 | Product(s) Referenced: lactacystin

Zvonic S., et al. (2005) "Cross-talk among gp130 Cytokines in Adipocytes." J. Biol. Chem. 280(40): 33856-33863.

PubMed ID: 16096272 | Product(s) Referenced: Epoxomicin

Bartee E., et al. (2004) "Downregulation of Major Histocompatibility Complex Class I by Human Ubiquitin Ligases Related to Viral Immune Evasion Proteins." J. Virol. 78(3): 1109-1120.

PubMed ID: 14722266 | Product(s) Referenced: lactacystin

Burstein E., et al. (2004) "A novel role for XIAP in copper homeostasis through regulation of MURR1." EMBO J. 23(1): 244-254.

PubMed ID: 14685266 | Product(s) Referenced: ubiquitin aldehyde

Gottifredi V., et al. (2004) "Decreased p21 Levels Are Required for Efficient Restart of DNA Synthesis after S Phase Block." J. Biol. Chem. 279(7): 5802-5810.

PubMed ID: 14597617 | Product(s) Referenced: beta-lactone

Habelhah H., et al. (2004) "Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-κB." EMBO J. 23(2): 322-332.

PubMed ID: 14713952 | Product(s) Referenced: Ub aldehyde

Hatao, F., et al. (2004) "Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein." J. Leukoc. Biol. 76(4): 904-908.

PubMed ID: 15258191 | Product(s) Referenced: Lactacystin

Mehle A., et al. (2004) "Vif Overcomes the Innate Antiviral Activity of APOBEC3G by Promoting Its Degradation in the Ubiquitin-Proteasome Pathway." J. Biol. Chem. 279(9): 7792-7798.

PubMed ID: 14672928 | Product(s) Referenced: clasto-lactacystin [beta]-lactone

Nishikawa H., et al. (2004) "Mass Spectrometric and Mutational Analyses Reveal Lys-6-linked Polyubiquitin Chains Catalyzed by BRCA1-BARD1 Ubiquitin Ligase." J. Biol. Chem. 279(6): 3916-3924.

PubMed ID: 14638690 | Product(s) Referenced: Ubal (ubiquitin aldehyde)

Reuter C. J. and Maupin-Furlow J.A. (2004) "Analysis of Proteasome-Dependent Proteolysis in Haloferax volcanii Cells, Using Short-Lived Green Fluorescent Proteins." Appl. Envir. Microbiol. 70(12): 7530-7538.

PubMed ID: 15574956 | Product(s) Referenced: clasto-Lactacystin [beta]-lactone

Reuter C. J. and Maupin-Furlow J.A. (2004) "Analysis of Proteasome-Dependent Proteolysis in Haloferax volcanii Cells, Using Short-Lived Green Fluorescent Proteins." Appl. Envir. Microbiol. 70(12): 7530-7538.

PubMed ID: 15574956 | Product(s) Referenced: clasto-Lactacystin [beta]-lactone

Sato K., et al. (2004) "Degradation of Fodrin by m-Calpain in Fibroblasts Adhering to Fibrillar Collagen I Gel." J. Biochem. (Tokyo) 136(6): 777-785.

PubMed ID: 15671488 | Product(s) Referenced: lactacystin

Song B.-L. and DeBose-Boyd R.A. (2004) "Ubiquitination of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Permeabilized Cells Mediated by Cytosolic E1 and a Putative Membrane-bound Ubiquitin Ligase." J. Biol. Chem. 279(27): 28798-28806.

PubMed ID: 15090540 | Product(s) Referenced: ubiquitin-aldehyde

Suzuki N., et al. (2004) "Proteasomal Degradation of the Nuclear Targeting Growth Factor Midkine." J. Biol. Chem. 279(17): 17785-17791.

PubMed ID: 14970216 | Product(s) Referenced: clasto-lactacystin [beta]-lactone

Zhang D. D., et al. (2004) "Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex." Mol. Cell. Biol. 24(24): 10941-10953.

PubMed ID: 15572695 | Product(s) Referenced: MG132

Chang, W., et al. (2003) "TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres." Genes & Dev. 17: 1328-1333.

PubMed ID: 12782650 | Product(s) Referenced: ubiquitin


PubMed ID: 23442071 | Product(s) Referenced: Ubiquitin-Protein Conjugation kit
PubMed ID: 23744067 | Product(s) Referenced: HeLa S100 Conjugation kit
PubMed ID: 23749209 | Product(s) Referenced: ubiquitination kit
PubMed ID: 23665951 | Product(s) Referenced: Ubiquitin-Protein Conjugation kit
PubMed ID: 24019521 | Product(s) Referenced: Ubiquitin Conjugation Initiation Kit

Lim, J.H. et al. (2012) "CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt." Nat Commun 3: 771

PubMed ID: 22491319 | Product(s) Referenced: In vitro ubiquitination and deubiquitination assay kit

Osula, O. et al. (2012) "Identification of protein SUMOylation sites by mass spectrometry using combined microwave-assisted aspartic acid cleavage and tryptic digestion." J Mass Spectrom 47(5): 644–654.

PubMed ID: 22576878 | Product(s) Referenced: SUMOylation kit containing SUMO-1

Zhou, X.H. et al. (2012) "A three generation study with high-lysine transgenic rice in Sprague-Dawley rats." Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association 50(6): 1902–1910.

PubMed ID: 22510491 | Product(s) Referenced: rat sex hormone ELISA kit

Guo, Z. et al. (2012) "Sequential Posttranslational Modifications Program FEN1 Degradation during Cell-Cycle Progression." Molecular cell.

PubMed ID: 22749529 | Product(s) Referenced: ubiquitination reaction buffer, UBE1, UBE2M, HeLa S100 fraction, SUMOylation kits, ubiquitination kit

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

PubMed ID: 21775430 | Product(s) Referenced: His-UbcH7

Sung, C.K., et al. (2011) “Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150Sal2.” The FASEB Journal fj.10-173674; published ahead of print January 12, 2011,doi:10.1096/fj.10-173674.

PubMed ID: 21228219 | Product(s) Referenced: ubiquitin conjugation reaction buffer kit (SK-10)

Dolan, P.J. and Johnson, G. (2010) “A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway.” J. Biol. Chem. 285: 21978 - 21987.

PubMed ID: 20466727 | Product(s) Referenced: UbcH5b

Cohen, S., et al. (2009) "During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation." J. Cell Biol. 185: 1083-1095.

PubMed ID: 19506036 | Product(s) Referenced: UbcH13, Uev1 E2-conjugating enzyme

Pacheco, C.D., et al. (2009) "Tau deletion exacerbates the phenotype of Niemann–Pick type C mice and implicates autophagy in pathogenesis." Hum. Mol. Genet. 18(5): 956-965.

PubMed ID: 19074461 | Product(s) Referenced: 20S Proteasome Assay Kit, SDS-Activation Format

Sun, L., et al. (2009) “JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.” PNAS 106: 10195-10200.

Product(s) Referenced: ubiquitin-protein conjugation kit

Stanisic, V., et al (2009) "OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER)a and Affects ERa Transcriptional Activity." J. Biol. Chem. 284: 16135-16145.

PubMed ID: 19383985 | Product(s) Referenced: ubiquitination kit, K-960

Marfella, R., et al. (2008) "Proteasome Activity as a Target of Hormone Replacement Therapy-Dependent Plaque Stabilization in Postmenopausal Women." Hypertension 51: 1135-41.

Product(s) Referenced: proteasome 20S SDS activation kit

Marfella, R., et al. (2008) "Effects of Ubiquitin-Proteasome System Deregulation on the Vascular Senescence and Atherosclerosis Process in Elderly Patients." J. Gerontol. A Biol. Sci. Med. Sci. 63: 200-3.

Product(s) Referenced: sodium dodecyl sulfate [SDS]-activation kit

Marfella, R., et al. (2007). "Morning Blood Pressure Surge as a Destabilizing Factor of Atherosclerotic Plaque: Role of Ubiquitin-Proteasome Activity." Hypertension 49(4): 784-791.

Product(s) Referenced: proteasome-20S SDS-activation kit