Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

Inhibitor

Bunce, M.W., et al. (2008) "Coordinated Activation of the Nuclear Ubiquitin Ligase Cul3-SPOP by the Generation of Phosphatidylinositol 5-Phosphate." J. Biol. Chem. 283: 8678-8686.

Product(s) Referenced: MG132

Choi, E. et al. (2008) "Unique D Box and KEN Box Sequences Limit Ubiquitination of Acm1 and Promote Pseudosubstrate Inhibition of the Anaphase-promoting Complex." J. Biol. Chem. 283(35): 23701-23710.

PubMed ID: 18596038 | Product(s) Referenced: ubiquitin aldehyde

Fernandez, A.F., et al. (2008) "Oxidative Inactivation of the Proteasome in Retinal Pigment Epithelial Cells: A POTENTIAL LINK BETWEEN OXIDATIVE STRESS AND UP-REGULATION OF INTERLEUKIN-8." J. Biol. Chem. 283(30): 20745-20753.

Product(s) Referenced: Epoxomicin

Graham, R., et al. (2008) "Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein." J. Gen. Virol. 81: 1913-1925.

PubMed ID: 10900028 | Product(s) Referenced: MG132

Jalonen U, et al. (2008) "Compounds That Increase or Mimic Cyclic Adenosine Monophosphate Enhance Tristetraprolin Degradation in Lipopolysaccharide-Treated Murine J774 Macrophages." J. Pharm. Exp. Ther. 326: 514-522.

PubMed ID: 18469159 | Product(s) Referenced: ubiquitin aldehyde

Koulich, E., et al. (2008) "Relative Structural and Functional Roles of Multiple Deubiquitylating Proteins Associated with Mammalian 26S Proteasome." Mol. Biol. Cell 19: 1072-82.

PubMed ID: 18162577 | Product(s) Referenced: ubiquitin vinylsulphone

Le Negrate, G., et al. (2008) "Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF-κB, Suppresses IκB[alpha] Ubiquitination and Modulates Innate Immune Responses." J. Immunol. 180: 5045-56.

PubMed ID: 18354230 | Product(s) Referenced: ubiquitin-aldehyde

Lin, JH-C., et al. (2008) "A Central Role of Connexin 43 in Hypoxic Preconditioning." J. Neurosci. 28: 681-95.

PubMed ID: 18199768 | Product(s) Referenced: epoxomicin

Mansouri, M., et al. (2008) "Remodeling of endothelial adherens junctions by Kaposi's sarcoma herpesvirus." J. Virol. 82(19):9615-9628.

PubMed ID: 18667499 | Product(s) Referenced: MG132

Miyauchi, Y., et al. (2008) "The COP9/signalosome increases the efficiency of pVHL ubiquitin ligase-mediated hypoxia inducible factor-[alpha] ubiquitination." J. Biol. Chem. 283 (24):16622-16631.

PubMed ID: 18424433 | Product(s) Referenced: ubiquitin aldehyde

Ogawa, M., et al. (2008) "Rines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligase." Genes Cells 13: 397-409.

PubMed ID: 18363970 | Product(s) Referenced: clasto-Lactacystin- [beta]-lactone

Oh Y.K., et al. (2008) "Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells." Mol. Canc. Res. 6: 1232-1249.

PubMed ID: 18644986 | Product(s) Referenced: ubiquitin aldehyde

Reis, J., et al. (2008) "A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model." Innate Immunity 14(5): 319-329.

PubMed ID: 18809656 | Product(s) Referenced: Lactacystin

Yamauchi, K., et al. (2008). "Ubiquitination of E3 ligase TRIM5[alpha] and its potential role." FEBS J. 275(7): 1540-1555.

PubMed ID: 18312418 | Product(s) Referenced: MG115

Yang Z., et al. (2008) "Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication." J. Virol. 82: 3590-603.

Product(s) Referenced: Ub aldehyde

Anderson, G.R., et al. (2007). "Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases." J. Neurosci. 27(51): 14117-14127.

PubMed ID: 18094251 | Product(s) Referenced: lactacystin

Ausseil, F., et al. (2007). "High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources." J. Biomol. Screen. 12(1): 106-116.

PubMed ID: 17175525 | Product(s) Referenced: Epoxomicin

Benson, M. D., et al. (2007). "SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5." PNAS 104(6): 1805-1810.

PubMed ID: 17261810 | Product(s) Referenced: lactacystin

Butler, M. P., et al. (2007). "Kinase active IRAKs promote polyubiquitination and degradation of the Pellino family: Direct evidence for Pellino proteins being E3 ubiquitin ligases." J. Biol. Chem. 282:29729-29737.

PubMed ID: 17675297 | Product(s) Referenced: wild-type ubiquitin

Demo, S. D., et al. (2007). "Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome." Cancer Res. 67(13): 6383-6391.

PubMed ID: 17616698 | Product(s) Referenced: clasto-lactacystin [beta]-lactone

Fielitz, J., et al. (2007). "Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3." J. Clin. Inv. 117(9): 2486-2495.

PubMed ID: 18502748 | Product(s) Referenced: beta-lactone

Forbes, A., et al. (2007). "The tetraspan protein EMP2 regulates expression of caveolin-1." J. Biol. Chem.: 282(36): 26542-26551.

PubMed ID: 17609206 | Product(s) Referenced: Epoxomicin

Gallagher, M. J., et al. (2007). "The GABAA receptor [alpha]1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation." PNAS 104(32): 12999-13004.

PubMed ID: 17670950 | Product(s) Referenced: lactacystin

Hong, K. U., et al. (2007). "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis." Mol. Cell. Biol. 27(10): 3667-3681.

PubMed ID: 17339342 | Product(s) Referenced: epoxomicin

Kamynina, E., et al. (2007). "Regulation of Proto-Oncogenic Dbl by Chaperone-Controlled, Ubiquitin-Mediated Degradation.” Mol. Cell. Biol. 27(5): 1809-1822.

PubMed ID: 17178836 | Product(s) Referenced: Clasto-lactacystin [beta]-lactone