Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

E2 Conjugating

Mo, P., et al. (2010) “MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3.” J. Biol. Chem. 285: 26908 - 26915.

PubMed ID: 20592017 | Product(s) Referenced: E2

Patel, D. and McCance, D. J. (2010) “Compromised Spindle Assembly Checkpoint due to Altered Expression of Ubch10 and Cdc20 in Human Papillomavirus Type 16 E6- and E7-Expressing Keratinocytes.” J. Virol. 84: 10956-10964.

Product(s) Referenced: Ubch10

Ramamoorthy, S., et al. (2010) “Isoform-Specific Degradation of PR-B by E6-AP Is Critical for Normal Mammary Gland Development.” Mol. Endocrinol. 24: 2099-2113.

PubMed ID: 20829392 | Product(s) Referenced: E2

Walters, M.S., et al. (2010) “The RING Finger Domain of Varicella-Zoster Virus ORF61p Has E3 Ubiquitin Ligase Activity That Is Essential for Efficient Autoubiquitination and Dispersion of Sp100-Containing Nuclear Bodies.” J. Virol. 84: 6861 - 6865.

PubMed ID: 20392849 | Product(s) Referenced: His-UbcH3, UbcH5c

Wu, T., et al. (2010) “UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex.” PNAS 107: 1355 - 1360.

PubMed ID: 20080579 | Product(s) Referenced: UbcH5a

Yang, Y., et al. (2010) “E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNF-induced JNK activation.” PNAS 107: 13444 - 13449.

PubMed ID: 20624960 | Product(s) Referenced: recombinant E2 (UbcH5)

Alvarez, S.E., et al. (2010) "Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.” Nature 465(7301): 1084–1088.

PubMed ID: 20577214 | Product(s) Referenced: UbcH13–Uev1a E2 complex, UbcH5–Uev1a E2 complex

Chu, Y. and Yang, X. (2010) "SUMO E3 ligase activity of TRIM proteins.” Oncogene 30(9): 1108–1116.

PubMed ID: 20972456 | Product(s) Referenced: Ubc9

Chymkowitch, P., et al. (2010) "The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.” The EMBO Journal 30(3): 468–479.

PubMed ID: 21157430 | Product(s) Referenced: E2 (GST-UbcH5a)

Dynek, J.N., et al. (2010) "c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.” The EMBO journal 29(24): 4198–4209.

PubMed ID: 21113135 | Product(s) Referenced: UbcH5a, UbcH5b, UbcH5c

Johnson, A.E. and Gould, K.L. (2010) "Dma1 ubiquitinates the SIN scaffold, Sid4, to impede the mitotic localization of Plo1 kinase.” The EMBO journal 30(2): 341–354.

PubMed ID: 21131906 | Product(s) Referenced: E2 (Ubc13/Uev1a)

Cohen, S., et al. (2009) "During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation." J. Cell Biol. 185: 1083-1095.

PubMed ID: 19506036 | Product(s) Referenced: UbcH1 E2-conjugating enzyme

Corcoran, C., et al. (2009) “Identification and Characterization of Two Novel Isoforms of Pirh2 Ubiquitin Ligase That Negatively Regulate p53 Independent of RING Finger Domains.” J. Biol. Chem. 284: 21955 – 21970 .

PubMed ID: 19483087

Enzler, T., et al. (2009) “MEKK1 Binds HECT E3 Ligase Itch by Its Amino-Terminal RING Motif to Regulate Th2 Cytokine Gene Expression.” J. Immunol. 183: 3831 - 3838.

PubMed ID: 19710465 | Product(s) Referenced: ubiquitination assay enzymes

Faustrup, H., et al. (2009) "USP7 counteracts SCF[beta]TrCP- but not APCCdh1-mediated proteolysis of Claspin." J. Cell Biol. 184(1):13-19.

PubMed ID: 19124652 | Product(s) Referenced: hUbcH5C

Fu, W., et al. (2009) "MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation." J. Biol. Chem. 284: 13987-14000.

PubMed ID: 19321440 | Product(s) Referenced: GST-Ubc5Hb

Isobe, T., et al. (2009) “Adenovirus E1A Inhibits SCFFbw7 Ubiquitin Ligase.” J. Biol. Chem. 284: 27766 - 27779.

PubMed ID: 19679664 | Product(s) Referenced: UbcH5c

Kadara, H., et al. (2009) “Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System.” Cancer Prevention Research 2: 702 - 711.

PubMed ID: 19638491

Merbl, Y. and Kirschner M.W. (2009) "Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays." PNAS 10 (8): 2543-2548.

PubMed ID: 19181856 | Product(s) Referenced: UbcH10

Sigl, R., et al. (2009) “Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis.” J. Cell Sci. 122: 4208 - 4217.

PubMed ID: 19861496 | Product(s) Referenced: UbcH10 (rb)

Bernal-Bayard, J. and Ramos-Morales, F. (2009) “Salmonella Type III Secretion Effector SlrP Is an E3 Ubiquitin Ligase for Mammalian Thioredoxin.” J. Biol. Chem. 284: 27587 - 27595.

PubMed ID: 19690162 | Product(s) Referenced: human recombinant UbcH5b

Burns, M., et al. (2009) "Parkin promotes intracellular A[beta]1–42 clearance." Hum. Mol. Genet. 18: 3206 - 3216.

PubMed ID: 19483198 | Product(s) Referenced: recombinant UbcH7

Cooper, E.M., et al. (2009) "K63-specific deubuiquitination by two JAMM/MPN+ complexes:BRISC-associated Brcc-36 and proteasomal Poh1." EMBO J. 28(6) 621-631.

PubMed ID: 19214193 | Product(s) Referenced: UbcH12

Koodathingal, P., et al. (2009) "ATP-dependent Proteases Differ Substantially in Their Ability to Unfold Globular Proteins." J. Biol. Chem. 284: 18674-18684.

PubMed ID: 19383601 | Product(s) Referenced: recombinant UbcH5a

Maerki, S., et al. (2009) “The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis.” J. Cell Biol. 187: 791 - 800.

PubMed ID: 19995937 | Product(s) Referenced: E2