Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

E2 Conjugating

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

PubMed ID: 20940148 | Product(s) Referenced: E2

Gannavaram, S., et al. (2011) “Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani.” PLoS one 6: e16156. doi:10.1371/journal.pone.0016156.

PubMed ID: 21264253 | Product(s) Referenced: Human recombinant Uba5

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

PubMed ID: 21775430 | Product(s) Referenced: E2

Zhu, F., et al. (2011) “Phosphorylation of H2AX at Ser139 and a New Phosphorylation Site Ser16 by RSK2 Decreases H2AX Ubiquitination and Inhibits Cell Transformation.” Cancer Research, 71: 393.

PubMed ID: 21224359 | Product(s) Referenced: recombinant UbcH5a

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

PubMed ID: 21795702 | Product(s) Referenced: UbcH7

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

PubMed ID: 21768287 | Product(s) Referenced: UBCH10, UBCH5

Galisson, F., et al. (2011) “A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells.” Molecular and Cellular Proteomics, 10: M110.004796.

PubMed ID: 21098080 | Product(s) Referenced: hUbC9, GST- RanGAP fragment 418–587

Hadian, K., et al. (2011) “NF-B Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-B Activation.” J. Biol. Chem. 286: 26107 - 26117.

PubMed ID: 21622571 | Product(s) Referenced: Lys-63 specific E2 complex UbcH13/Uev1a

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

PubMed ID: 21258371 | Product(s) Referenced: His–Ubc H3, His–Ubc H5

Jones, J., et al. (2011) “The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3.” Immunology Letters, 2: 156-162.

PubMed ID: 1256161 | Product(s) Referenced: UbcH2

Kim, J., et al (2011) “Role of TRIM5[alpha] RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus.” J. Virol. 85: 8116 - 8132.

PubMed ID: 21680520 | Product(s) Referenced: UbcH5a

Lin, D., et al. (2011) “Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.” The Journal of Biological Chemistry, 286: 441-449.

PubMed ID: 20980253 | Product(s) Referenced: E2 enzymes

Lu, J., et al. (2011) “RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation.” J. Biol. Chem. 286: 24426 - 24433.

PubMed ID: 21610068 | Product(s) Referenced: UbcH5b

Lu, K., et al. (2011) “Pivotal role of the SMURF1 C2 domain in substrate selection.” The Journal of Biological Chemistry: doi:10.1074/jbc.M110.211979.

PubMed ID: 21402695 | Product(s) Referenced: UbcH5c (E2)

Mao, X., et al. (2011) “COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding.” J. Biol. Chem. 286: 32355 - 32365.

PubMed ID: 21778237 | Product(s) Referenced: human His6-E1 (Uba1), UbcH10, UbcH3, UbcH5a, UbcH5b, UbcH5c, UbcH7

Meisenberg, C., et al. (2011) “Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.” Nucleic Acids Res. 10.1093/nar/gkr744.

PubMed ID: 21933813 | Product(s) Referenced: E2

Nagel, C., et al. (2011) “Herpes Simplex Virus Immediate-Early Protein ICP0 Is Targeted by SIAH-1 for Proteasomal Degradation.” J. Virol. 85: 7644 - 7657.

PubMed ID: 21632771 | Product(s) Referenced: ubiquitin-conjugating enzyme UbcH5b

Shibata, E., et al. (2011) “Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex.” Mol. Cell. Biol. 31: 3136 - 3145.

PubMed ID: 21628527 | Product(s) Referenced: recombinant UBCH5C

Sung, C.K., et al. (2011) “Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150Sal2.” The FASEB Journal fj.10-173674; published ahead of print January 12, 2011,doi:10.1096/fj.10-173674.

PubMed ID: 21228219 | Product(s) Referenced: UbcH5c (E2-627)

Wang, Y., et al. (2011) “The ubiquitin-dependent proteasomal degradation (UPD) of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and Ubiquitination.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.176685 .

PubMed ID: 21209460 | Product(s) Referenced: UbcH5a

Wu, K., et al. (2011) “Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1.” J. Biol. Chem. 286: 34060 - 34070

PubMed ID: 21813641 | Product(s) Referenced: APP-BP, Uba3, Ubc12, UbcH5c

Zhang, N., et al. (2011) “Ubiquitin Chain Trimming Recycles the Substrate Binding Sites of the 26 S Proteasome and Promotes Degradation of Lysine 48-linked Polyubiquitin Conjugates.” J. Biol. Chem. 286: 25540 - 25546.

PubMed ID: 21632534 | Product(s) Referenced: UbcH10

Zhao, R., et al. (2011) “Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.” JCI, 121: 851-865.

PubMed ID: 21317535 | Product(s) Referenced: E2 (E2-622)

Cui, Y., et al. (2011) "SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.” The EMBO Journal 30(13): 2675–2689.

PubMed ID: 21572392 | Product(s) Referenced: UbcH5c

Fischer, E.S., et al. (2011) "The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation.” Cell 147(5): 1024–1039.

PubMed ID: 22118460 | Product(s) Referenced: hsUbcH5A, hsUbcH5B