Product References

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

E2 Conjugating

Wu, J. et al. (2012) "Skp2 E3 Ligase Integrates ATM Activation and Homologous Recombination Repair by Ubiquitinating NBS1." Molecular cell. 2012 Mar 28;

PubMed ID: 22464731 | Product(s) Referenced: E1, UBCH5c

Osula, O. et al. (2012) "Identification of protein SUMOylation sites by mass spectrometry using combined microwave-assisted aspartic acid cleavage and tryptic digestion." J Mass Spectrom 47(5): 644–654.

PubMed ID: 22576878 | Product(s) Referenced: E2-25K substrate

Sambuughin, N. et al. (2012) "KBTBD13 interacts with Cullin 3 to form a functional ubiquitin ligase." Biochemical and biophysical research communications. 2012 Apr 20;

PubMed ID: 22542517 | Product(s) Referenced: E2-UbcH5a

An, J.Y. et al. (2012) "UBR2 of the N-End Rule Pathway Is Required for Chromosome Stability via Histone Ubiquitylation in Spermatocytes and Somatic Cells." PLoS ONE 7(5): e37414.

PubMed ID: 22616001 | Product(s) Referenced: HR6B

Guo, H. et al. (2012) "E3 Ubiquitin Ligase Cbl-b Regulates Pten via Nedd4 in T Cells Independently of Its Ubiquitin Ligase Activity." Cell Reports 1: 472–482.

PubMed ID: 10.1016/j.celrep.2012.04.008 | Product(s) Referenced: Ubc H5

Guo, H. et al. (2012) "E3 Ubiquitin Ligase Cbl-b Regulates Pten via Nedd4 in T Cells Independently of Its Ubiquitin Ligase Activity." Cell Reports 1: 472–482.

PubMed ID: 10.1016/j.celrep.2012.04.008 | Product(s) Referenced: Ubc5

Liu, Y. et al. (2012) "NF-κB Repression by PIAS3 Mediated RelA SUMOylation." PLoS ONE 7(5): e37636.

PubMed ID: 22649547 | Product(s) Referenced: Ubc9

Xin, D.-W. et al. (2012) "Functional Analysis of NopM, a Novel E3 Ubiquitin Ligase (NEL) Domain Effector of Rhizobium sp. Strain NGR234." PLoS Pathog. 8(5): e1002707.

PubMed ID: 22615567 | Product(s) Referenced: UbcH5B (E2)

Milhollen, M.A. et al. (2012) "Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924." Cancer Cell 21(3): 388–401.

PubMed ID: 22439935 | Product(s) Referenced: UBC10

Luo, K. et al. (2012) "Sumoylation of MDC1 is important for proper DNA damage response." The EMBO journal.  2012 May 25.

PubMed ID: 22635276 | Product(s) Referenced: E2

Chen, J. et al. (2012) "The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling." Genes Dev. 26(8): 803–815.

PubMed ID: 22508726 | Product(s) Referenced: Ubch5a

Gontan, C. et al. (2012) "RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation." Nature 485(7398): 386–390.

PubMed ID: 22596162 | Product(s) Referenced: UBCH5A

Luo, K. et al. (2012) "Sumoylation of MDC1 is important for proper DNA damage response." The EMBO journal.  2012 May 25;

PubMed ID: 22635276 | Product(s) Referenced: UbcH5a

Pulvino, M. et al. (2012) "Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A." Blood.

PubMed ID: 22791293 | Product(s) Referenced: anti-UbcH5

Hu, R. et al. (2012) "Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer." Cancer research.

PubMed ID: 22710436 | Product(s) Referenced: anti-UBE2C

Maezawa, S. et al. (2012) "Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity." PLoS ONE 7(7): e39511.

PubMed ID: 22808041 | Product(s) Referenced: rabbit pAb against UbcH5, rabbit pAb against UbcH6, rabbit pAb against UbcH7

Bai, L. et al. (2012) "UHRF2, another E3 ubiquitin ligase for p53." Biochemical and Biophysical Research Communications(0).

PubMed ID: 22902639 | Product(s) Referenced: E1, E2 (UbcH5a)

Chung, D.-W.D. et al. (2012) "Characterization of the Ubiquitylating Components of the Human Malaria Parasite’s Protein Degradation Pathway." PLoS ONE 7(8): e43477.

PubMed ID: 22912882 | Product(s) Referenced: re-energizing buffer, human recombinant UBE1 E1, Suc-LLVY-AMC, human recombinant UBC E2, biotin conjugated ubiquitin, ubiquitin,

Cohen, S. et al. (2012) "Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy." J. Cell Biol. 198(4): 575–589.

PubMed ID: 22908310 | Product(s) Referenced: UbcH13, Uev1 E2-conjugating enzyme

Gerard, B. et al. (2012) "Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin." Biochimica et biophysica acta.

PubMed ID: 22705350 | Product(s) Referenced: catalytically inactive rad6B, wild-type Rad6B

Guo, Z. et al. (2012) "Sequential Posttranslational Modifications Program FEN1 Degradation during Cell-Cycle Progression." Molecular cell.

PubMed ID: 22749529 | Product(s) Referenced: ubiquitination reaction buffer, UBE1, UBE2M, HeLa S100 fraction, SUMOylation kits, ubiquitination kit

Hoxhaj, G. et al. (2012) "ZNRF2 is released from membranes by growth factors and with ZNRF1 regulates the Na+/K+ATPase." Journal of cell science.

PubMed ID: 22797923 | Product(s) Referenced: E1 ubiquitin ligase, Ubc13/UEV1a, UbcH5a, ubiquitin

Janzer, A. et al. (2012) "The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology and the metabolome of fibroblasts." The Journal of biological chemistry.

PubMed ID: 22825849 | Product(s) Referenced: GST-UBC5a  human  recombinant protein

Johnson, A.E. et al. (2012) "Fission Yeast Dma1 Requires RING Domain Dimerization for Its Ubiquitin Ligase Activity and Mitotic Checkpoint Function." J. Biol. Chem.

PubMed ID: 10.1074/jbc.M112.349712 | Product(s) Referenced: recombinant E1, Ubc13/Uev1 E2 complex,

Avila, J. and Devarenne, T.P. (2012) "Ubiquitination of the tomato cell death suppressor Adi3 by the RING E3 Ubiquitin Ligase AdBiL." Biochem. Biophys. Res. Commun.

PubMed ID: 23178567 | Product(s) Referenced: FLAG tagged ubiquitin, Human E2s from the UbcH Enzyme Set