Product References - Proteasome

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

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23540790 | purified human constitutive 20S proteasome
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23318177 | 26S proteosomes
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23318177 | purified recombinant 19S RP
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23150437 | purified human 26S proteasomes
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23302496 | 20S rabbit proteosome
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23393593 | inhibitor LC

Gobec, M. et al. (2012) "Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition." PLoS ONE 7(7): e41961.

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22860040 | purified human 20S proteasome

Zhu, Y. et al. (2012) "Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols." J. Agric. Food Chem. 60(35): 8624–8631.

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22897570 | human 20S proteasome, proteasome activator PA28, Suc-Leu-Leu-Val-Tyr-AMC (Suc-LLVY-AMC)

Zhao, X. et al. (2012) "Orai1 mediates exacerbated ca(2+) entry in dystrophic skeletal muscle." PLoS ONE 7(11): e49862.

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23185465 | lactacystin

Zhang, Z. et al. (2012 "1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity." J. Biol. Inorg. Chem. 17(8): 1257–1267.

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23053530 | purified human 20S proteasome, human ubiquitin activating enzyme E1, UbcH10

Xu, X. et al. (2012) "Identification of insulin receptor substrate 1’s degradation determinants for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination." J. Biol. Chem. 287(48):40758-66.

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23045529 | E1, MG132

Blackburn C, Barrett C, Blank JL, et al. "Optimization of a series of dipeptides with a P3 β-neopentyl asparagine residue as non-covalent inhibitors of the chymotrypsin-like activity of human 20S proteasome." Med. Chem. Commun. 2012 May 30;3(6):710–719. 

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10.1039/C2MD20060K | purified human erythrocyte and peripheral blood monocyte 20S proteasomes, recombinant proteasomal activator PA28alpha, Z-LLE-AMC

Held, S.A.E. et al. (2012) "Imatinib mesylate and nilotinib affect MHC-class I presentation by modulating the proteasomal processing of antigenic peptides." Cancer Immunol. Immunother.

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23184338 | isolated and purified 20S proteasomes

Lu, B. et al. (2012) "Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA(+) Lon Protease." Mol. Cell.

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23201127 | 20S proteasome

Henle, A.M. et al. (2012) "Enzymatic Discovery of a HER-2/neu Epitope That Generates Cross-Reactive T Cells." J. Immunol.

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23180824 | Suc-LLVY-AMC, synthetic lactacystin, reaction buffer (25 mM HEPES, 0.5 mM EDTA, pH 7.6), immunoproteasome, PA28 activator alpha subunit, purified human 20S proteasome

Guan, B. et al. (2012) "Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions." Neoplasia 14(10): 986–993.

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23097632 | MG132

Dechavanne, V. et al. (2012) "Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC-MS." Protein Expr. Purif.

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23147206 | Rabbit AP-123 polyclonal antibody, anti-beta2-20S human proteasome

Burrows, A.C. et al. (2012) "Skp1-Cul1-F-box Ubiquitin Ligase (SCFβTrCP)-Mediated Destruction of the Ubiquitin-Specific Protease USP37 During G2-phase Promotes Mitotic Entry." J. Biol. Chem.

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23027877 | MG132, UbcH10 antibody

Foy, R.L. et al. (2012) "Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1." Hum. Mol. Genet.

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23001567 | lactacystin, MG132

Carvalho, A.N. et al. (2012) "Ubiquitin-Proteasome System Impairment and MPTP-Induced Oxidative Stress in the Brain of C57BL/6 Wild-type and GSTP Knockout Mice." Mol. Neurobiol.

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23129554 | Z-leucine-leucine-glutamic acid-7-amido-4-methylcoumarin (Z-LLE-AMC), Boc-leucine-arginine-arginine-7-amido-4-methylcoumarin (Boc-LRR-AMC), succcinyl-leucine-leucine-valine-tyro-sine-7-amido-4-methylcoumarin (Suc-LLVY-AMC), isopeptidase inhibitor (Ubiquitin aldehyde [Ubal]), MG132,

Ismail, A. et al. (2012) "Proteasome Inhibitory Potential of Commonly Consumed Dietary Ingredients." International Journal of Food and Nutrition Science 1(4): 27–31.

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| 20S proteasome purified from rabbit

Lansdell, T.A. et al. (2012) "Non-competitive modulation of the proteasome by imidazoline scaffolds overcome bortezomib resistant and delay MM tumor growth in vivo." ACS Chem. Biol.

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23198928 | purified proteasome particles, Suc-LLVY-AMC, Z-ARR-AMC, Z-LLE-AMC

Blount, J.R. et al. (2012) "Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation." PLoS ONE 7(5): e36542.

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22590560 | MG132

Chollangi, S. et al. (2012) "The hemerythrin-like domain within F-box and leucine-rich repeat protein 5 communicates cellular iron and oxygen availability by distinct mechanisms." The Journal of biological chemistry. 2012 May 30;

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22648410 | MG132

Zhang, Y. et al. (2012) "Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1." Proc. Natl. Acad. Sci. U.S.A. 109(15): 5717–5722.

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22451935 | MG132

Kensche, T. et al. (2012) "Analysis of NF-κB essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB." The Journal of biological chemistry. 2012 May 17;

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22605335 | ubiquitin aldehyde

Chen, J. et al. (2012) "The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling." Genes Dev. 26(8): 803–815.

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22508726 | MG132

Niño, C.A. et al. (2012) "The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation." Acta tropica. 2012 Apr 4.

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22498829 | MG132

Bernstein, S.H. et al. (2012) "The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives." Blood 119(14): 3321–3329.

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22323447 | 20S proteasome

Gustin, J.K. et al. (2012) "Ubiquitination of BST-2 Protein by HIV-1 Vpu Protein Does Not Require Lysine, Serine, or Threonine Residues within the BST-2 Cytoplasmic Domain." J. Biol. Chem. 287(18): 14837–14850.

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22383521 | MG132

Issaenko, O.A. and Amerik, A.Y. (2012) "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes." Cell cycle (Georgetown, Tex.) 11(9).

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22510564 | Ubiquitin aldehyde (Ubal), 20S Human proteasome

Long, M.J.C. et al. (2012) "Inhibitor Mediated Protein Degradation." Chemistry & Biology 19(5): 629–637.

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22633414 | immunoproteasome from mouse spleen, Purified 20S proteasome from HeLa, IU1

Thompson, J.W. et al. (2012) "Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5)." J. Biol. Chem. 287(10): 7357–7365.

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22253436 | MG132

Tsihlis, N.D. et al. (2012) "Nitric oxide decreases activity and levels of the 11S proteasome activator PA28 in the vasculature." Nitric Oxide 27(1): 50–58.

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22561112 | recombinant PA28, Bz-VGR-AMC (trypsin-like), Suc-LLVY-AMC (chymotrypsin-like), Z-LLE-AMC (caspase-like)

Xu, H. et al. (2012) "The CCAAT box-binding transcription factor NF-Y regulates basal expression of human proteasome genes." Biochim. Biophys. Acta 1823(4): 818–825.

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22285817 | MG132, Suc-Leu-Leu-Val-Tyr-AMC pep- tide substrate

Zheng, J. et al. (2012) "Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis." J. Neurochem. 121(3): 486–494.

22353035 | immunoproteasome, standard proteasome

Issaenko, O.A. and Amerik, A.Y. (2012) "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes." Cell cycle (Georgetown, Tex.) 11(9).

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22510564 | 20S Human proteasome , e-360

Bernstein, S.H. et al. (2012) "The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives." Blood 119(14): 3321–3329.

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22323447 | 20S proteasome

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

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21364033 | MG-132

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

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21364033 | MG-132

Bulut, G., et al. (2011) “Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor.” The Journal of Biological Chemistry, 286: 6449-6457.

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21183685 | Lactacystin

Chen, L., et al. (2011) “Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus.” The Journal of Biological Chemistry, 286: 3104-3118.

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21075847 | LLVY-AMC

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Z-LRGG-AMC

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

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21163868 | MG-132

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

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21163868 | MG-132

Dammer, E., et al. (2011) “Polyubiquitin linkage profiles in three models of proteolytic stress suggest etiology of Alzheimer disease.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.149633.

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21278249 | epoxomicin

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

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20940148 | lactacystin

Emanuele, M.J., et al. (2011) "Global Identification of Modular Cullin-RING Ligase Substrates.” Cell 147(2): 459–474.

21963094 | MG132

Foley, E.A., et al. (2011) "Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.” Nature Cell Biology 13(10): 1265–1271.

21874008 | MG132

Huang, Y., et al. (2011) “UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation.” Mol. Bio. of the Cell: doi:10.1091/mbc.E10-10-0827.

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21307340 | MG132

Jo, Y., et al. (2011) “Membrane-associated Ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.211326.

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21343306 | MG-132

Li, H., et al. (2011) "Regulation of NF-[kappa]B activity by competition between RelA acetylation and ubiquitination.” Oncogene. 31(5):611-23.

21706061 | MG-132

Mi, L., et al. (2011) “Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.” Carginogenesis, 32: 216-223.

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21109604 | purified 20S proteasome extracted from rabbit erythrocytes

Obaidat, A., et al. (2011) “Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs.” Jour. of Pharm. and Exp. Therapeutics: doi:10.1124/jpet.110.177824.

21303921 | Suc-LLVY-AMC

Solis, M., et al. (2011) “RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I.” Journal of Virology, 85: 1224-1236.

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21084468 | MG132

Sun, H., et al. (2011) “Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.” Blood, 117: 3151-3162.

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21248063 | MG-132

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

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21807946 | MG132

Lin, D., et al. (2011) “Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.” The Journal of Biological Chemistry, 286: 441-449.

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20980253 | mutant Ubs

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.*.

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21177809 | proteasome inhibitor MG132

Dasmahapatra, G., et al. (2010) "The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo." Blood. 115: 4478 - 4487.

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20233973 | Suc-LLVY-7-amino-4-methylcoumarin

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.

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21177809 | proteasome inhibitor MG132

Bauer, S., et al. (2010) “Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells.” Cancer Res. 70: 150 - 159.

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20028860 | MG-132

Byun, H., et al. (2010) “Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function.” PNAS 107: 12287 - 12292.

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20566871 | MG132

Dasmahapatra, G., et al. (2010) "The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo." Blood. 115: 4478 - 4487.

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20233973 | Suc-LLVY-7-amino-4-methylcoumarin

Ensminger, A. and Isberg, R. (2010) “E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.” Infect. Immun., 78: 3905 - 3919.

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20547746 | ubiquitin aldehyde

Fouladkou, F., et al. (2010) “The Ubiquitin Ligase Nedd4-1 Is Required for Heart Development and Is a Suppressor of Thrombospondin.” J. Biol. Chem. 285: 6770 - 6780.

| MG132

Hartman, I.Z., et al. (2010) "Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets." J. Biol. Chem. 285: 19288 - 192 .

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20406816 | MG-132

Chandra, A., et al. (2010) “Proteasome Assembly Influences Interaction with Ubiquitinated Proteins and Shuttle Factors.” J. Biol. Chem. 285: 8330 - 8339.

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20061387 | Suc-LLVY-AMC

Korzeniewski, N., et al. (2010) “Daughter Centriole Elongation Is Controlled by Proteolysis.” Mol. Biol. Cell 21: 3942-3951.

| lactacystin

Lee, C.-M., et al. (2010) “Metabolism and Action of Proteasome Inhibitors in Primary Human Hepatocytes.” Drug Metab. Dispos. 38: 2166-2172.

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20837660 | epoxomicin, clasto-lactacystin-[beta]-lactone, MG132

Liang, J., et al. (2010) “MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-B signaling.” J. Exp. Med. 207: 2959-2973.

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21115689 | MG132, ubiquitin aldehyde

Liu, J. and Ma, J. (2010) "Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos.” Nature cell biology 13(1): 22–29.

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21170036 | MG132

Maine, G.N., et al. (2010) "A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis.” Nat. Protocols 5(8): 1447–1459.

20671728 | MG-132

Plafker, K.S., et al. (2010) “The Ubiquitin-conjugating Enzyme UbcM2 Can Regulate the Stability and Activity of the Antioxidant Transcription Factor Nrf2.” J. Biol. Chem. 285: 23064 - 23074.

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20484052 | MG132

Screen, M., et al. (2010) “Nature of Pharmacophore Influences Active Site Specificity of Proteasome Inhibitors.” J. Biol. Chem. 285: 40125-40134.

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20937826 | MG-262

Wang, X., et al (2010) “Regulation of the 26S Proteasome Complex During Oxidative Stress.” Sci. Signal. 3: ra88.

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21139140 | SUC-ARR-AMC, SUC-LLE-AMC, SUC-LLVY-AMC

Wang, X.H., et al. (2010). “Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity.” J. Biol. Chem. 285: 21249 - 21257.

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20424172 | ubiquitin-aldehyde (Ubal)

Berthouze, M., et al. (2009) "The deubiquitinases USP33 and USP20 coordinate [beta]2 adrenergic receptor recycling and resensitization.” The EMBO journal 28(12): 1684–1696.

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19424180 | Isopeptidase T

Bruce, S.R., et al (2009) "Respiratory Syncytial Virus (RSV) Infection Alters Surfactant Protein-A (SP-A) Expression in Human Pulmonary Epithelial Cells by Reducing Translation Efficiency." Am J Physiol Lung Cell Mol Physiol: 90507.2008.

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19525387 | 20S Proteasome Assay Kit

Busso, C.S., et al. (2009) "Ubiquitination of mammalian AP endonuclease (APE1) "regulated by the p53–MDM2 signaling pathway.” Oncogene 28(13): 1616–1625.

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19219073 | MG132

Douglas JL, Viswanathan K, McCarroll MN, Gustin JK, Fruh K, Moses AV. (2009) "Vpu Directs the Degradation of the HIV Restriction Factor BST-2/tetherin via a bTrCP-dependent Mechanism." J. Virol.: JVI.00242-09. 

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19515779 | MG132

Fernandes, A., et al. (2009) “Proteasome Inactivation Promotes p38 Mitogen-activated Protein Kinase-dependent Phosphatidylinositol 3-kinase Activation and Increases Interleukin-8 Production in Retinal Pigment Epithelial Cells.” Mol. Biol. Cell 20: 3690.

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http://www.molbiolcell.org/content/20/16/3690.long | Epoxomicin

Ikeda, Y., et al. (2009) “Regulated Endoplasmic Reticulum-associated Degradation of a Polytopic Protein: p97 Recruits Proteasomes to Insig-1 Before Extraction From Membranes.” J. Biol. Chem. 284: 34889 - 34900.

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19815544 | MG-132

Lin, G., et al. (2009) "Inhibitors selective for mycobacterial versus human proteasomes.” Nature 461(7264): 621–626.

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19759536 | Hu20S (from human red blood cells), PA28

Middeldorp J., et al. (2009) "Intermediate filament transcription in astrocytes is repressed by proteasome inhibition." FASEB J: fj.08-127696.* .

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19332645 | MG262

Liu, Z., et al. (2009) "Human BRE1 Is an E3 Ubiquitin Ligase for Ebp1 Tumor Suppressor." Mol. Biol. Cell 20 (3): 757-768.

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19037095 | clastolactacystin [beta]-lactone

Mao, X,. et al. (2009) "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kB/RelA." Genes & Dev. 23: 849-861.

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19339690 | MG-132

Mitra, S., et al. (2009) "Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease." J. Biol. Chem. 284(7): 4398-4403.

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19074152 | epoxomicin

Parlati, F., et al. (2009) “Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome.” Blood 114: 3439 - 3447.

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19671918 | human c20S, human i20S

Persaud, A., et al. (2009) "Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.” Molecular systems biology 5(1).

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19953087 | MG132

Rousseau, E., et al. (2009) "Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones." J. Biol. Chem. 284(3): 1917-1929.

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18986984 | purified 19S proteasome

Rybak, A., et al. (2009) "The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.” Nature Cell Biology 11(12): 1411–1420.

19898466 | MG132

Shen, H-W., et al. (2009) "Altered Dendritic Spine Plasticity in Cocaine-Withdrawn Rats." J. Neurosci. 29 (9): 2876-2884.

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19261883 | 20 s proteasome subunit (subunit [alpha]5)

Wang, X., et al. (2009). “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

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19951915 | MG132

Wang, Z.Q., et al. (2009). "Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys." Diabetes 58: 1488-1498.

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19336678 | MG132

Xia, Z.P., et al. (2009) "Direct activation of protein kinases by unanchored polyubiquitin chains.” Nature 461(7260): 114–119.

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19675569 | IsoT

Yuksek, K., et al. (2009) "Ubiquitin-Independent Degradation of Hepatitis C Virus F Protein." J. Virol. 83(2): 612-621.

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18971267 | 20S proteasome

Zmijewski, J., et al. (2009) “S-Glutathionylation of the Rpn2 Regulatory Subunit Inhibits 26 S Proteasomal Function.” J. Biol. Chem. 284: 22213 - 22221.

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19549781 | anti-Rpn1

Balastik, M., et al. (2008) "Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration." PNAS 105 (33): 12016-12021.

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18687884 | MG-132

Baldin, V., et al. (2008) "A Novel Role for PA28γ-Proteasome in Nuclear Speckle Organization and SR Protein Trafficking." Mol. Biol. Cell 19: 1706-16.

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18256291 | MG132

Balastik, M., et al. (2008) "Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration." PNAS 105 (33): 12016-12021.

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18687884 | MG-132

Baldin, V., et al. (2008) "A Novel Role for PA28γ-Proteasome in Nuclear Speckle Organization and SR Protein Trafficking." Mol. Biol. Cell 19: 1706-16.

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18256291 | MG132

Bunce, M.W., et al. (2008) "Coordinated Activation of the Nuclear Ubiquitin Ligase Cul3-SPOP by the Generation of Phosphatidylinositol 5-Phosphate." J. Biol. Chem. 283: 8678-8686.

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18218622 | MG132

Fernandez, A.F., et al. (2008) "Oxidative Inactivation of the Proteasome in Retinal Pigment Epithelial Cells: A POTENTIAL LINK BETWEEN OXIDATIVE STRESS AND UP-REGULATION OF INTERLEUKIN-8." J. Biol. Chem. 283(30): 20745-20753.

| Epoxomicin

Graham, R., et al. (2008) "Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein." J. Gen. Virol. 81: 1913-1925.

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10900028 | MG132

Hedhli, N., et al. (2008) "Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22." Cardiovasc. Res. 77: 497-505.

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18006445 | Suc-LLVY-AMC

Hedhli, N., et al. (2008) “Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload.” Am. J. Physiol. Heart. Circ. Physiol. 295 (4): H1385-H1393.

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18676687 | Suc-LLVY-AMC

Jin, L., et al. (2008) "Mechanism of Ubiquitin-Chain Formation by the human Anaphase-Promoting Complex.” Cell 133(4): 653–665.

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18485873 | purified human 26S proteasomes

Lin, G., et al. (2008) "Distinct Specificities of Mycobacterium tuberculosis and Mammalian Proteasomes for N-Acetyl Tripeptide Substrates." J. Biol. Chem. 283(49): 34423-34431.

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18829465 | human RBC 20S

Lin, JH-C., et al. (2008) "A Central Role of Connexin 43 in Hypoxic Preconditioning." J. Neurosci. 28: 681-95.

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18199768 | lactacystin, MG132

Mansouri, M., et al. (2008) "Remodeling of endothelial adherens junctions by Kaposi's sarcoma herpesvirus." J. Virol. 82(19):9615-9628.

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18667499 | MG132

McClung, J.M., et al. (2008) "Redox regulation of diaphragm proteolysis during mechanical ventilation." Am J Physiol Regulatory Integrative Comp Physiol: 294(5):R1608-1617.

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18321950 | proteasome-activating complex PA28

Oh Y.K., et al. (2008) "Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells." Mol. Canc. Res. 6: 1232-1249.

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18644986 | ubiquitin aldehyde

Yamauchi, K., et al. (2008). "Ubiquitination of E3 ligase TRIM5[alpha] and its potential role." FEBS J. 275(7): 1540-1555.

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18312418 | MG132

Lamothe, B., et al. (2007). "Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation." J. Biol. Chem. 282(6):Determinant of I 4102-4112.

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17135271 | WT ubiquitin

Anderson, G.R., et al. (2007). "Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases." J. Neurosci. 27(51): 14117-14127.

| lactacystin

Ausseil, F., et al. (2007). "High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources." J. Biomol. Screen. 12(1): 106-116.

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17175525 | Epoxomicin

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Ausseil, F., et al. (2007). "High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources." J. Biomol. Screen. 12(1): 106-116.

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Smith, I. J. and S. L. Dodd (2007). "Muscle: Calpain activation causes a proteasome-dependent increase in protein degradation and inhibits the Akt signalling pathway in rat diaphragm muscle." Exp Physiol 92(3): 561-573.

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Ye, Z., et al. (2007) "Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination." Am. J. Pathol. 171: 882-892.

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14722266 | lactacystin

Bartee E., et al. (2004) "Downregulation of Major Histocompatibility Complex Class I by Human Ubiquitin Ligases Related to Viral Immune Evasion Proteins." J. Virol. 78(3): 1109-1120.

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15671488 | lactacystin

Zhang D. D., et al. (2004) "Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex." Mol. Cell. Biol. 24(24): 10941-10953.

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