Product References - Inhibitor

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

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23475958 | ubiquitin aldehyde
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23318177 | 19S inhibitor b-AP15
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epoximycin | 23437325
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23535459 | MG132
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23486064 | ubiquitin aldehyde
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23424652 | HA-Ub vinyl sulfone
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23458873 | MG-132 proteosome inhibitor
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23541081 | MG-132
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23541081 | ubiquitin aldehyde
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23449802 | ubiquitin aldehyde
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23512198 | ubiquitin aldehyde

Zhang, S. et al. (2012) "GST:Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage." J. Biol. Chem.

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23233665 | ATP regenerating solution (ENS), ubiquitin aldehyde, HeLa S100 fraction, Recombinant human E1 ubiquitin activating enzyme, Recombinant human ubiquitin, Recombinant human ubiquitin K48R, Recombinant human ubiquitin K63R, Recombinant human UbcH5c, Recombinant human Cdc34, Recombinant human UbcH2

Frisan, T. et al. (2012) "Ubiquitin C-terminal hydrolase-L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth." FASEB J.

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22932395 | Ub-VS functional probe

Henle, A.M. et al. (2012) "Enzymatic Discovery of a HER-2/neu Epitope That Generates Cross-Reactive T Cells." J. Immunol.

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23180824 | Suc-LLVY-AMC, synthetic lactacystin, reaction buffer (25 mM HEPES, 0.5 mM EDTA, pH 7.6), immunoproteasome, PA28 activator alpha subunit, purified human 20S proteasome

Guan, B. et al. (2012) "Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions." Neoplasia 14(10): 986–993.

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23097632 | MG132

Cosper, P.F. et al. (2012) "Interferon-γ Causes Cardiac Myocyte Atrophy via Selective Degradation of Myosin Heavy Chain in a Model of Chronic Myocarditis." Am. J. Pathol. 181(6): 2038–2046.

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23058369 | MG-132

Carvalho, A.N. et al. (2012) "Ubiquitin-Proteasome System Impairment and MPTP-Induced Oxidative Stress in the Brain of C57BL/6 Wild-type and GSTP Knockout Mice." Mol. Neurobiol.

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23129554 | Z-leucine-leucine-glutamic acid-7-amido-4-methylcoumarin (Z-LLE-AMC), Boc-leucine-arginine-arginine-7-amido-4-methylcoumarin (Boc-LRR-AMC), succcinyl-leucine-leucine-valine-tyro-sine-7-amido-4-methylcoumarin (Suc-LLVY-AMC), isopeptidase inhibitor (Ubiquitin aldehyde [Ubal]), MG132,

Caldeira, M.V. et al. (2012) "Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons." Biochim. Biophys. Acta.

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23069389 | HA-Ub-VS

Blount, J.R. et al. (2012) "Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation." PLoS ONE 7(5): e36542.

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22590560 | MG132

Chollangi, S. et al. (2012) "The hemerythrin-like domain within F-box and leucine-rich repeat protein 5 communicates cellular iron and oxygen availability by distinct mechanisms." The Journal of biological chemistry. 2012 May 30;

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22648410 | MG132

Zhang, Y. et al. (2012) "Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1." Proc. Natl. Acad. Sci. U.S.A. 109(15): 5717–5722.

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22451935 | MG132

Kensche, T. et al. (2012) "Analysis of NF-κB essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB." The Journal of biological chemistry. 2012 May 17;

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22605335 | ubiquitin aldehyde

Long, M.J.C. et al. (2012) "Inhibitor Mediated Protein Degradation." Chemistry & Biology 19(5): 629–637.

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22633414 | IU1

Tsuji, T. et al. (2012) "Heat Shock Protein 90-Mediated Peptide-Selective Presentation of Cytosolic Tumor Antigen for Direct Recognition of Tumors by CD4+ T Cells." J. Immunol. 188(8): 3851–3858.

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22427632 | epoxomicin

Long, M.J.C. et al. (2012) "Inhibitor Mediated Protein Degradation." Chemistry & Biology 19(5): 629–637.

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22633414 | lactacystin

Tsuji, T. et al. (2012) "Heat Shock Protein 90-Mediated Peptide-Selective Presentation of Cytosolic Tumor Antigen for Direct Recognition of Tumors by CD4+ T Cells." J. Immunol. 188(8): 3851–3858.

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22427632 | lactacystin

Gastaldello, S. et al. (2012) "Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1." Journal of molecular cell biology. 2012 Apr 3;

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22474075 | Nedd8-VS

Chen, J. et al. (2012) "The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling." Genes Dev. 26(8): 803–815.

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22508726 | MG132

Niño, C.A. et al. (2012) "The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation." Acta tropica. 2012 Apr 4.

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22498829 | MG132

Gastaldello, S. et al. (2012) "Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1." Journal of molecular cell biology. 2012 Apr 3;

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22474075 | Ub-VS

Gustin, J.K. et al. (2012) "Ubiquitination of BST-2 Protein by HIV-1 Vpu Protein Does Not Require Lysine, Serine, or Threonine Residues within the BST-2 Cytoplasmic Domain." J. Biol. Chem. 287(18): 14837–14850.

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22383521 | MG132

Issaenko, O.A. and Amerik, A.Y. (2012) "Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes." Cell cycle (Georgetown, Tex.) 11(9).

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22510564 | Ubiquitin aldehyde (Ubal), 20S Human proteasome

Long, M.J.C. et al. (2012) "Inhibitor Mediated Protein Degradation." Chemistry & Biology 19(5): 629–637.

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22633414 | immunoproteasome from mouse spleen, Purified 20S proteasome from HeLa, IU1

Niño, C.A. et al. (2012) "The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation." Acta tropica. 2012 Apr 4.

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22498829 | ubiquitin-aldehyde

Thompson, J.W. et al. (2012) "Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5)." J. Biol. Chem. 287(10): 7357–7365.

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22253436 | MG132

Xu, H. et al. (2012) "The CCAAT box-binding transcription factor NF-Y regulates basal expression of human proteasome genes." Biochim. Biophys. Acta 1823(4): 818–825.

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22285817 | MG132, Suc-Leu-Leu-Val-Tyr-AMC pep- tide substrate

Kensche, T. et al. (2012) "Analysis of Nuclear Factor-κB (NF-κB) Essential Modulator (NEMO) Binding to Linear and Lysine-linked Ubiquitin Chains and Its Role in the Activation of NF-κB." J. Biol. Chem. 287(28): 23626–23634.

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22605335 | creatine phosphokinase, HeLa-S-100 fraction II, ubiquitin, ubiquitin aldehyde

Basters, A. et al. (2012) "High yield expression of catalytically active USP18 using a Trigger Factor fusion system." BMC Biotechnol. 12(1): 56.

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22916876 | HA-ISG15 vinyl sulfone (ISG15-VS), ISG15-amidomethyl coumarin (AMC), HA-Ubiquitin (Ub-VS)

Herr, R.A. et al. (2012) "Newly Discovered Viral E3 Ligase pK3 Induces Endoplasmic Reticulum-associated Degradation of Class I Major Histocompatibility Proteins and Their Membrane-bound Chaperones." J. Biol. Chem. 287(18): 14467–14479.

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22403403 | deubiquiting enzyme inhibitor ubiquitin aldehyde, proteasome inhibitor MG132

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

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21364033 | MG-132

Bulut, G., et al. (2011) “Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor.” The Journal of Biological Chemistry, 286: 6449-6457.

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21183685 | Lactacystin

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.

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21343341 | ubiquitin aldehyde

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Ub-VS

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

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21163868 | MG-132, ubiquitin aldehyde

Dammer, E., et al. (2011) “Polyubiquitin linkage profiles in three models of proteolytic stress suggest etiology of Alzheimer disease.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.149633.

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21278249 | MG‐132

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

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20940148 | MG132

Feltham, R., et al. (2011) “SMAC-mimetics activate the E3 ligase activity of cIAP1 by promoting RING dimerisation.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M111.222919.

21393245 | MG132

Foley, E.A., et al. (2011) "Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.” Nature Cell Biology 13(10): 1265–1271.

21874008 | MG132

Huang, L., et al. (2011) "Hydrophobicity as a driver of MHC class I antigen processing.” The EMBO Journal 30(8): 1634–1644.

21378750 | epoxomicin

Huang, Y., et al. (2011) “UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation.” Mol. Bio. of the Cell: doi:10.1091/mbc.E10-10-0827.

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21307340 | MG132

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

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21258371 | ubiquitin aldehyde

Jo, Y., et al. (2011) “Membrane-associated Ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.211326.

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21343306 | MG-132

Li, H., et al. (2011) "Regulation of NF-[kappa]B activity by competition between RelA acetylation and ubiquitination.” Oncogene. 31(5):611-23.

21706061 | MG-132

Solis, M., et al. (2011) “RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I.” Journal of Virology, 85: 1224-1236.

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21084468 | MG132

Stringer, D. and Piper, R. (2011) “A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT Ubiquitination.” JCB, 192: 229-242.

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21242292 | Ub-Aldehyde

Sun, H., et al. (2011) “Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.” Blood, 117: 3151-3162.

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21248063 | lactacystin

Tanioka, T., et al. (2011) “Inducible Nitric-oxide Synthase and Nitric Oxide Donor Decrease Insulin Receptor Substrate-2 Protein Expression by Promoting Proteasome-dependent Degradation in Pancreatic [beta]-Cells: INVOLVEMENT OF GLYCOGEN SYNTHASE KINASE-3[beta].” J.

21700708 | lactacystin

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

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21807946 | MG132

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.* 

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21177809 | proteasome inhibitor MG132

Bauer, S., et al. (2010) “Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells.” Cancer Res. 70: 150 - 159.

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20028860 | MG-262

Byun, H., et al. (2010) “Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function.” PNAS 107: 12287 - 12292.

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20566871 | lactacystin

Chandra, A., et al. (2010) “Proteasome Assembly Influences Interaction with Ubiquitinated Proteins and Shuttle Factors.” J. Biol. Chem. 285: 8330 - 8339.

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20061387 | Epoxomicin

Clapp, K. M., et al. (2010) “C331A Mutant of Neuronal Nitric-oxide Synthase Is Labilized for Hsp70/CHIP (C Terminus of HSC70-interacting Protein)-dependent Ubiquitination.” J. Biol. Chem. 285: 33642-33651.

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20729196 | ubiquitin-activating enzyme (E1)

de Thonel, A., et al. (2010) “HSP27 controls GATA-1 protein level during erythroid cell differentiation.” Blood116: 85 - 96.

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20410505 | Ubiquitin-Protein Conjugation Kit

Dolan, P.J. and Johnson, G. (2010). “A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway.” J. Biol. Chem. 285: 21978 - 21987.

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20466727 | HA-ubiquitin

Emanuele, M.J., et al. (2011) "Global Identification of Modular Cullin-RING Ligase Substrates.” Cell 147(2): 459–474.

21963094 | MG132

Ensminger, A. and Isberg, R. (2010) “E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.” Infect. Immun., 78: 3905 - 3919.

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20547746 | ubiquitin aldehyde

Fouladkou, F., et al. (2010) “The Ubiquitin Ligase Nedd4-1 Is Required for Heart Development and Is a Suppressor of Thrombospondin-.” J. Biol. Chem. 285: 6770 - 6780.

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20026598 | MG132

Fujita, K., et al. (2010) "Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.” Nature cell biology 12(12): 1205–1212.

21057505 | ubiquitin aldehyde

Hallows, K.R., et al. (2010) “Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel.” J. Biol. Chem. 285: 21671 - 21678.

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20466724 | HA-tagged ubiquitin

Hartman, I.Z., et al. (2010) "Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets." J. Biol. Chem. 285: 19288 - 192.

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20406816 | MG-132

Kops, G., et al. (2010) "APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome." J. Cell Sci. 123: 1623 - 1633.

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20392738 | HA-ubiquitin

Korzeniewski, N., et al. (2010) “Daughter Centriole Elongation Is Controlled by Proteolysis.” Mol. Biol. Cell 21: 3942-3951.

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20861314 | lactacystin

Lee, B.H., et al. (2010) "Enhancement of proteasome activity by a small-molecule inhibitor of USP14.” Nature 467(7312): 179–184.

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20829789 | Ub–VS

Lee, C.-M., et al. (2010) “Metabolism and Action of Proteasome Inhibitors in Primary Human Hepatocytes.” Drug Metab. Dispos. 38: 2166-2172.

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20837660 | epoxomicin, clasto-lactacystin-[beta]-lactone, MG132

Liang, J., et al. (2010) “MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-B signaling.” J. Exp. Med. 207: 2959-2973.

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21115689 | MG132, ubiquitin aldehyde

Liu, J. and Ma, J. (2010) "Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos.” Nature cell biology 13(1): 22–29.

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21170036 | MG132

Maine, G.N., et al. (2010) "A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis.” Nat. Protocols 5(8): 1447–1459.

20671728 | MG-132

Plafker, K.S., et al. (2010) “The Ubiquitin-conjugating Enzyme UbcM2 Can Regulate the Stability and Activity of the Antioxidant Transcription Factor Nrf2.” J. Biol. Chem. 285: 23064 - 23074.

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20484052 | MG132

Screen, M., et al. (2010) “Nature of Pharmacophore Influences Active Site Specificity of Prot

http://www.jbc.org/content/285/51/40125.long

easome Inhibitors.” J. Biol. Chem. 285: 40125-40134.

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20937826 | MG-132

Burnett, B.G., et al. (2009) "Regulation of SMN Protein Stability." Mol. Cell. Biol. 29(5): 1107-1115.

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19103745 | ubiquitin aldehyde

Busso, C.S., et al. (2009) "Ubiquitination of mammalian AP endonuclease (APE1) "regulated by the p53–MDM2 signaling pathway.” Oncogene 28(13): 1616–1625.

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19219073 | MG132

Douglas JL, Viswanathan K, McCarroll MN, Gustin JK, Fruh K, Moses AV. (2009) "Vpu Directs the Degradation of the HIV Restriction Factor BST-2/tetherin via a bTrCP-dependent Mechanism." J. Virol.: JVI.00242-09.* .

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19515779 | MG132

Fernandes, A., et al. (2009) “Proteasome Inactivation Promotes p38 Mitogen-activated Protein Kinase-dependent Phosphatidylinositol 3-kinase Activation and Increases Interleukin-8 Production in Retinal Pigment Epithelial Cells.” Mol. Biol. Cell 20: 3690 -.

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19570915 | Epoxomicin

Ikeda, Y., et al. (2009) “Regulated Endoplasmic Reticulum-associated Degradation of a Polytopic Protein: p97 Recruits Proteasomes to Insig-1 Before Extraction From Membranes.” J. Biol. Chem. 284: 34889 - 34900.

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19815544 | MG-132

Kilroy, G.E., et al. (2009) "PPAR-[gamma] AF-2 Domain Functions as a Component of a Ubiquitin-dependent Degradation Signal.” Obesity 17(4): 665–673.

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19148122 | epoxomicin

Kim, A.H., et al. (2009) "A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons.” Cell 136(2): 322–336.

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19167333 | ubiquitin aldehyde

Mao, X,. et al. (2009) "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kB/RelA." Genes & Dev. 23: 849-861.

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19339690 | MG-132

Middeldorp J., et al. (2009) "Intermediate filament transcription in astrocytes is repressed by proteasome inhibition." FASEB J: fj.08-127696.*.

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19332645 | MG262

Mitra, S., et al. (2009) "Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease." J. Biol. Chem. 284(7): 4398-4403.

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19074152 | epoxomicin

Nakao, R., et al. (2009) "Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloading." Mol. Cell. Biol.: MCB.01347-08.

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19546233 | ubiquitin-aldehyde

Persaud, A., et al. (2009) "Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.” Molecular systems biology 5(1).

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19953087 | MG132

Sorkhy, M.A., et al. (2009) "The Cyclin-dependent Kinase Activator, Spy1A, Is Targeted for Degradation by the Ubiquitin Ligase NEDD4." J. Biol. Chem. 284(5): 2617-2627.

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19054764 | lactacystin

Todi, S.V., et al. (2009) "Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3.” The EMBO journal 28(4): 372–382.

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19153604 | lactacystin

Wang, X., et al. (2009) “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

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19951915 | MG132

Wang, Z.Q., et al. (2009) "Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys." Diabetes 58: 1488-1498.

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19336678 | epoxomicin

Balastik, M., et al. (2008) "Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration." PNAS 105 (33): 12016-12021.

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18687884 | MG-132

Baldin, V., et al. (2008) "A Novel Role for PA28γ-Proteasome in Nuclear Speckle Organization and SR Protein Trafficking." Mol. Biol. Cell 19: 1706-16.

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18256291 | MG132

Bunce, M.W., et al. (2008) "Coordinated Activation of the Nuclear Ubiquitin Ligase Cul3-SPOP by the Generation of Phosphatidylinositol 5-Phosphate." J. Biol. Chem. 283: 8678-8686.

| MG132

Choi, E. et al. (2008) "Unique D Box and KEN Box Sequences Limit Ubiquitination of Acm1 and Promote Pseudosubstrate Inhibition of the Anaphase-promoting Complex." J. Biol. Chem. 283(35): 23701-23710.

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18596038 | ubiquitin aldehyde

Fernandez, A.F., et al. (2008) "Oxidative Inactivation of the Proteasome in Retinal Pigment Epithelial Cells: A POTENTIAL LINK BETWEEN OXIDATIVE STRESS AND UP-REGULATION OF INTERLEUKIN-8." J. Biol. Chem. 283(30): 20745-20753.

| Epoxomicin

Graham, R., et al. (2008) "Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein." J. Gen. Virol. 81: 1913-1925.

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10900028 | MG132

Jalonen U, et al. (2008) "Compounds That Increase or Mimic Cyclic Adenosine Monophosphate Enhance Tristetraprolin Degradation in Lipopolysaccharide-Treated Murine J774 Macrophages." J. Pharm. Exp. Ther. 326: 514-522.

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18469159 | ubiquitin aldehyde

Koulich, E., et al. (2008) "Relative Structural and Functional Roles of Multiple Deubiquitylating Proteins Associated with Mammalian 26S Proteasome." Mol. Biol. Cell 19: 1072-82.

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18162577 | ubiquitin vinylsulphone

Le Negrate, G., et al. (2008) "Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF-κB, Suppresses IκB[alpha] Ubiquitination and Modulates Innate Immune Responses." J. Immunol. 180: 5045-56.

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18354230 | ubiquitin-aldehyde

Lin, JH-C., et al. (2008) "A Central Role of Connexin 43 in Hypoxic Preconditioning." J. Neurosci. 28: 681-95.

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18199768 | epoxomicin

Mansouri, M., et al. (2008) "Remodeling of endothelial adherens junctions by Kaposi's sarcoma herpesvirus." J. Virol. 82(19):9615-9628.

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18667499 | MG132

Miyauchi, Y., et al. (2008) "The COP9/signalosome increases the efficiency of pVHL ubiquitin ligase-mediated hypoxia inducible factor-[alpha] ubiquitination." J. Biol. Chem. 283 (24):16622-16631.

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18424433 | ubiquitin aldehyde

Ogawa, M., et al. (2008) "Rines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligase." Genes Cells 13: 397-409.

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18363970 | clasto-Lactacystin- [beta]-lactone

Oh Y.K., et al. (2008) "Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells." Mol. Canc. Res. 6: 1232-1249.

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18644986 | ubiquitin aldehyde

Reis, J., et al. (2008) "A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model." Innate Immunity 14(5): 319-329.

18809656 | Lactacystin

Yamauchi, K., et al. (2008). "Ubiquitination of E3 ligase TRIM5[alpha] and its potential role." FEBS J. 275(7): 1540-1555.

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18312418 | MG115

Yang Z., et al. (2008) "Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication." J. Virol. 82: 3590-603.

| Ub aldehyde

Anderson, G.R., et al. (2007). "Expression and Localization of RGS9-2/Gb5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases." J. Neurosci. 27(51): 14117-14127.

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18094251 | lactacystin

Ausseil, F., et al. (2007). "High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources." J. Biomol. Screen. 12(1): 106-116.

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17175525 | Epoxomicin

Benson, M. D., et al. (2007). "SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5." PNAS 104(6): 1805-1810.

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17261810 | lactacystin

Butler, M. P., et al. (2007). "Kinase active IRAKs promote polyubiquitination and degradation of the Pellino family: Direct evidence for Pellino proteins being E3 ubiquitin ligases." J. Biol. Chem. 282:29729-29737.

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17675297 | wild-type ubiquitin

Demo, S. D., et al. (2007). "Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome." Cancer Res. 67(13): 6383-6391.

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17616698 | clasto-lactacystin [beta]-lactone

Fielitz, J., et al. (2007). "Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3." J. Clin. Inv. 117(9): 2486-2495.

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18502748 | beta-lactone

Forbes, A., et al. (2007). "The tetraspan protein EMP2 regulates expression of caveolin-1." J. Biol. Chem.: 282(36): 26542-26551.

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17609206 | Epoxomicin

Gallagher, M. J., et al. (2007). "The GABAA receptor [alpha]1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation." PNAS 104(32): 12999-13004.

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17670950 | lactacystin

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