Product References - E3 ligase

Boston Biochem's products have been used successfully in hundreds of UPP-related publications. We have listed our most recent references below to provide our customers with an exceptional resource for product use information. The references are organized to mirror our product divisions for easy location. Products referenced in each article are listed below in red. Please inquire to request archives as we have curated references back to 2003.

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23512198 | his-purified recombinant Cullin 1
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23512198 | his-purified recombinant Rbx1
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23512198 | his-purified recombinant Skp1

Cotto-Rios, X.M. et al. (2012) "Deubiquitinases as a signaling target of oxidative stress." Cell Rep 2(6): 1475–1484.

23219552 | UbVME, recombinant ubiquitin chain K48-linked, UCH-L1, SENP1-CD, STAM, recombinant ubiquitin chain K63-linked, SUMO1-vs, USP7, AMSH,

Hou, X. et al. (2012) "Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis." BMC Genomics 13: 495.

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22992278 | MYC-ubiquitin, purified recombinant E2 (UBE2D2/UBCH5B), purified recombinant E2 (UBE2D3/UBCH5C), purified recombinant E2 (Ube2k/E2-25K), purified recombinant E2 (UBE2L3/ UBCH7), putative E3s with GST tag, yeast E1

Burchell, L. et al. (2012) "Small, N-terminal tags activate parkin e3 ubiquitin ligase activity by disrupting its autoinhibited conformation." PLoS ONE 7(4): e34748.

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22496854 | His-Parkin

Johnson, B.N. et al. (2012) "The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax." Proc. Natl. Acad. Sci. U.S.A. 109(16): 6283–6288.

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22460798 | UbcH7

Schneider, S. et al. (2012) "Development of a homogeneous AlphaLISA ubiquitination assay using ubiquitin binding matrices as universal components for the detection of ubiquitinated proteins." Biochimica et biophysica acta. 2012 Apr 5.

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22504171

Johnson, B.N. et al. (2012) "The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax." Proc. Natl. Acad. Sci. U.S.A. 109(16): 6283–6288.

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22460798

Kalia, L.V., et al. (2011) “Ubiquitinylation of [alpha]-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5).” PloS one, 6: e14695. doi:10.1371/journal.pone.0014695 .

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21358815 | HDM2, MuRF1

Bosanac, I., et al. (2011) “Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.” Journal of Mol. Bio.: doi:10.1016/j.jmb.2011.03.011.* .

21396940 | MURF1

Shin, J., et al. (2011) “PARIS (ZNF746) Repression of PGC-1[alpha] Contributes to Neurodegeneration in Parkinson's Disease.” Cell, 144: 689-702.

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21376232 | His-Parkin

Jin, X, et al. (2010) “An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-B-inducing Kinase via Lys63-linked Ubiquitination.” J. Biol. Chem. 285: 30539-30547.

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20682767 | Lys63-only ubiquitin

Kaneko, M., et al. (2010) “Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-[beta] Generation.” J. Neurosci., 3924 - 3932.

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20237263 | RP-HRD1 (E3)

Chymkowitch, P., et al. (2010) "The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.” The EMBO Journal 30(3): 468–479.

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21157430 | MDM2

Fu, W., et al. (2009) "MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation." J. Biol. Chem. 284: 13987-14000.

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19321440 | MDM2

Siepe, D. and Jentsch, S. (2009) "Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation.” Nature Cell Biology 11(8): 967–972.

19597489 | recombinant E3 (His6-Mdm2)

Newton, K., et al. (2008) "Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies.” Cell 134(4): 668–678.

18724939 | MuRF1 autoubiquitination reactions

Hrecka, K., M. Gierszewska, et al. (2007). "Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle." PNAS 104(28): 11778-11783.

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17609381

Fortier, J. M. and J. Kornbluth (2006). "NK Lytic-Associated Molecule, Involved in NK Cytotoxic Function, Is an E3 Ligase." J. Immunol. 176(11): 6454-6463.

| Polyclonal UbcH8 Ab

Dai, M.-S., D. et al. (2006). "Regulation of the MDM2-p53 Pathway by Ribosomal Protein L11 Involves a Post-ubiquitination Mechanism." J. Biol. Chem. 281(34): 24304-24313.

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16803902 | purified human recombinant E2 (UbcH5a)

Burstein E., et al. (2004) "A novel role for XIAP in copper homeostasis through regulation of MURR1." EMBO J. 23(1): 244-254.

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14685266 | E3