Product References - E1 activating

Bae, S. et al. (2012) "Akt is negatively regulated by the MULAN E3 ligase." Cell Res. 22(5): 873–885.

Liu, C. et al. (2012) "CHFR is important for the first wave of ubiquitination at DNA damage sites." Nucleic Acids Res.

Chung, D.-W.D. et al. (2012) "Characterization of the Ubiquitylating Components of the Human Malaria Parasite’s Protein Degradation Pathway." PLoS ONE 7(8): e43477.

Hoxhaj, G. et al. (2012) "ZNRF2 is released from membranes by growth factors and with ZNRF1 regulates the Na+/K+ATPase." Journal of cell science.

Zhang, Z. et al. (2012 "1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity." J. Biol. Inorg. Chem. 17(8): 1257–1267.

Xu, X. et al. (2012) "Identification of insulin receptor substrate 1’s degradation determinants for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination." J. Biol. Chem. 287(48):40758-66.

Viquez, O.M. et al. (2012) "Electrophilic Adduction of Ubiquitin Activating Enzyme E1 by N,N-Diethyldithiocarbamate Inhibits Ubiquitin Activation and is Accompanied by Striatal Injury in the Rat." Chem. Res. Toxicol.

Shen, R.R. et al. (2012) "IKK{epsilon} phosphorylates TRAF2 to promote mammary epithelial cell transformation." Mol. Cell. Biol. 32(23):4756-68. 

Matta-Camacho, E. et al. (2012) "Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase." Acta Crystallographica Section F Structural Biology and Crystallization Communications 68(10): 1158–1163.

Jung, Y.-S. et al. (2012) "Pirh2 E3 Ubiquitin Ligase Modulates Keratinocyte Differentiation through p63." J. Invest. Dermatol.

Humphrey, R.K. et al. (2012) "Lysine 63-linked Ubiquitination Modulates Mixed Lineage Kinase-3 Interaction with JIP1 Scaffold protein in Cytokine-induced Pancreatic Beta Cell Death." J. Biol. Chem.

Hou, X. et al. (2012) "Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis." BMC Genomics 13: 495.

Hernandez-Ortega, S. et al. (2012) "Defective in Mitotic Arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation." J. Biol. Chem.

Bai, L. et al. (2012) "UHRF2, another E3 ubiquitin ligase for p53." Biochemical and Biophysical Research Communications(0).

Luo, K. et al. (2012) "Sumoylation of MDC1 is important for proper DNA damage response." The EMBO journal.  2012 May 25;

Bae, S. et al. (2012) "Akt is negatively regulated by the MULAN E3 ligase." Cell Res. 22(5): 873–885.

Xin, D.-W. et al. (2012) "Functional Analysis of NopM, a Novel E3 Ubiquitin Ligase (NEL) Domain Effector of Rhizobium sp. Strain NGR234." PLoS Pathog. 8(5): e1002707.

Woodsmith, J. et al. (2012) "Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks." Molecular & cellular proteomics: MCP. 2012 Apr 11;

Gontan, C. et al. (2012) "RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation." Nature 485(7398): 386–390.

Bae, S. et al. (2012) "Akt is negatively regulated by the MULAN E3 ligase." Cell Res. 22(5): 873–885.

Guo, H. et al. (2012) "E3 Ubiquitin Ligase Cbl-b Regulates Pten via Nedd4 in T Cells Independently of Its Ubiquitin Ligase Activity." Cell Reports 1: 472–482.

Sambuughin, N. et al. (2012) "KBTBD13 interacts with Cullin 3 to form a functional ubiquitin ligase." Biochemical and biophysical research communications. 2012 Apr 20;

Luo, K. et al. (2012) "Sumoylation of MDC1 is important for proper DNA damage response." The EMBO journal.  2012 May 25;

Shabbeer, S. et al. (2012) "BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation." Oncogene.

Zou, C., et al. (2011) “LPS Impairs Phospholipid Synthesis by Triggering [beta]-Transducin Repeat-containing Protein ([beta]-TrCP)-mediated Polyubiquitination and Degradation of the Surfactant Enzyme Acyl-CoA:Lysophosphatidylcholine Acyltransferase I (LPCAT1).”

Hyuk Lee, D., et al. (2011) “The Pepper E3 Ubiquitin Ligase RING1 Gene, CaRING1, Is Required for Cell Death and the Salicylic Acid-Dependent Defense Response.” Plant Physiology 156: 2011 - 2025.

Zhu, M., et al. (2011) “Pheromone- and RSP5-dependent Ubiquitination of the G Protein [beta] Subunit Ste4 in Yeast.” J. Biol. Chem. 286: 27147 - 27155.

Bocik, W., et al. (2011) “Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2G2.” The Journal of Biological Chemistry, 286: 3981-3991.

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

Cheng, P., et al. (2011) “Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development.” Neuron, 69: 231-243.

Bocik, W., et al. (2011) “Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2G2.” The Journal of Biological Chemistry, 286: 3981-3991.

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” 

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

Hessa, T., et al. (2011) "Protein targeting and degradation are coupled for elimination of mislocalized proteins.” Nature 475(7356): 394–397.

Huang, H.S., et al. (2011) "Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.” Nature 481(7380): 185–189.

Hyuk Lee, D., et al. (2011) “The Pepper E3 Ubiquitin Ligase RING1 Gene, CaRING1, Is Required for Cell Death and the Salicylic Acid-Dependent Defense Response.” Plant Physiology 156: 2011 - 2025.

Jones, J., et al. (2011) “The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3.” Immunology Letters, 2: 156-162.

Kassmeier, M.D., et al. (2011) "VprBP binds full-length RAG1 and is required for B-cell development and V (D) J recombination fidelity.” The EMBO Journal. 31(4):945-58.

Lu, J., et al. (2011) “RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation.” J. Biol. Chem. 286: 24426 - 24433.

Maddika, S., et al. (2011) "WWP2 is an E3 ubiquitin ligase for PTEN.” Nature cell biology 13(6): 730–735.

Nagel, C., et al. (2011) “Herpes Simplex Virus Immediate-Early Protein ICP0 Is Targeted by SIAH-1 for Proteasomal Degradation.” J. Virol. 85: 7644 - 7657.

Pinato, S., et al. (2011) “UMI, a Novel RNF168 Ubiquitin Binding Domain Involved in the DNA Damage Signaling Pathway.” Molecular and Cellular Biology, 31: 118-126.

Song, M.S., et al. (2011) "Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner.” Cell 144(2): 187–199.

Sung, C.K., et al. (2011) “Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150Sal2.” The FASEB Journal fj.10-173674; published ahead of print January 12, 2011,doi:10.1096/fj.10-173674.

Tsz-Mei Lok, G., et al. (2011) “Differential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylation.” Nucleic Acids Res. 10.1093/nar/gkr655.

Wu, K., et al. (2011) “Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1.” J. Biol. Chem. 286: 34060 - 34070.

Zhang, Y., et al. (2011) "RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.” Nature Cell Biology 13(5): 623–629.

Zhu, M., et al. (2011) “Pheromone- and RSP5-dependent Ubiquitination of the G Protein [beta] Subunit Ste4 in Yeast.” J. Biol. Chem. 286: 27147 - 27155.

Aghajan, M., et al. (2010) "Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.” Nat Biotech 28(7): 738–742.

Banerjee, S., et al. (2010) “Modulation of SCF[beta]-TrCP-dependent IB Ubiquitination by Hydrogen Peroxide.” J. Biol. Chem. 285: 2665 - 2675.

D’Angiolella, V., et al. (2010) "SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation.” Nature 466(7302): 138–142.

Ensminger, A. and Isberg, R. (2010) “E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.” Infect. Immun., 78: 3905 - 3919.

Hallows, K.R., et al. (2010) “Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel.” J. Biol. Chem. 285: 21671 - 21678.

Kaneko, M., et al. (2010) “Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-[beta] Generation.” J. Neurosci., 3924 - 3932.

Li, X.S., et al. (2010) "Mammalian SWI/SNF-A Subunit BAF250/ARID1 Is an E3 Ubiquitin Ligase That Targets Histone H2B." Mol. Cell. Biol. 30: 1673 - 1688.

Mo, P., et al. (2010) “MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3.” J. Biol. Chem. 285: 26908 - 26915.

Priest, C., et al. (2010) “Deconstructing nucleotide binding activity of the Mdm2 RING domain.” Nucleic Acids Res. 10.1093/nar/gkq669.

Walters, M.S., et al. (2010) “The RING Finger Domain of Varicella-Zoster Virus ORF61p Has E3 Ubiquitin Ligase Activity That Is Essential for Efficient Autoubiquitination and Dispersion of Sp100-Containing Nuclear Bodies.” J. Virol. 84: 6861 - 6865.

Xie, Y., et al. (2010) "SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor." Genes & Dev. 24: 893 - 903.

Bernal-Bayard, J. and Ramos-Morales, F. (2009) “Salmonella Type III Secretion Effector SlrP Is an E3 Ubiquitin Ligase for Mammalian Thioredoxin.” J. Biol. Chem. 284: 27587 - 27595.

Corcoran, C., et al. (2009) “Identification and Characterization of Two Novel Isoforms of Pirh2 Ubiquitin Ligase That Negatively Regulate p53 Independent of RING Finger Domains.” J. Biol. Chem. 284: 21955 – 21970.

Faustrup, H., et al. (2009) "USP7 counteracts SCF[beta]TrCP- but not APCCdh1-mediated proteolysis of Claspin." J. Cell Biol. 184(1):13-19.

Hwang, X-S., et al. (2009) "Two proteolytic pathways regulate DNA repair by co-targeting the Mgt1 alkylguanine transferase." PNAS 106(7): 2142-2147.

Kim, A.H., et al. (2009) "A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons.” Cell 136(2): 322–336.

Koodathingal, P., et al. (2009) "ATP-dependent Proteases Differ Substantially in Their Ability to Unfold Globular Proteins." J. Biol. Chem. 284: 18674-18684.

Li, W., et al. (2009) "Mechanistic insights into active site-associated poly-ubiquitination by the ubiquitin-conjugating enzyme Ube2g2." PNAS 106(10): 3722-3727.

Longerich, S., et al. (2009) “FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL.” J. Biol. Chem. 284: 23182 - 23186.

Mao, X,. et al. (2009) "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kB/RelA." Genes & Dev. 23: 849-861.

Nakao, R., et al. (2009) "Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloading." Mol. Cell. Biol.: MCB.01347-08.

Quezada, C.M., et al. (2009) "A family of Salmonella virulence factors functions as a distinct class of auto-regulated E3 ubiquitin ligases." PNAS 106 (12): 4864-4869.

Siepe, D. and Jentsch, S. (2009) "Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation.” Nature Cell Biology 11(8): 967–972.

Todi, S.V., et al. (2009) "Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3.” The EMBO journal 28(4): 372–382.

Wang, X., et al. (2009) “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

Varfolomeev E., et al. (2008) "c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor [alpha](TNF[alpha])-induced NF-κB Activation." J. Biol. Chem. 283(36): 24295-24299.

Brooks, W.S., et al. (2008) "G2E3 Is a Dual Function Ubiquitin Ligase Required for Early Embryonic Development." J. Biol. Chem. 283(32): 22304-22315.

Chitalia, V.C., et al. (2008) "Jade-1 inhibits Wnt signalling by ubiquitylating [beta]-catenin and mediates Wnt pathway inhibition by pVHL.” Nature cell biology 10(10): 1208–1216.

Conze, D.B., et al. (2008) “Lys63-Linked Poly-ubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation.” Mol. Cell. Biol. 28: 3538-47.

Durfee L.A,. et al (2008) "The Basis for Selective E1-E2 Interactions in the ISG15 Conjugation System." J. Biol. Chem. 283(35):23895-23902 .

Guardavaccaro, D., et al. (2008) "Control of chromosome stability by the [beta]-TrCP–REST–Mad2 axis.” Nature 452(7185): 365–369.

Karagianni, P., et al. (2008) "ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation" Mol. Cell. Biol. 28: 705-17.

Lovly C.M., et al. (2008) "Regulation of Chk2 Ubiquitination and Signaling through Autophosphorylation of Serine 379." Mol. Cell. Biol. 28(19): 5874-5885.

Lui, Q.Y., et al. (2008). "A novel brain-enriched E3 ubiquitin ligase RNF182 is up-regulated in the brains of Alzheimer’s patients and targets ATP6VOC for degradation." Molec. Degen. 3:4.

Malakhova O.A. and Zhang D-E. (2008) "ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response." J. Biol. Chem. 283: 8783-8787.

Ohtsubo M., et al. (2008) "Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity." PNAS 105(30): 10396-10401.

Sehat B, et al. (2008). "Identification of c-Cbl as a New Ligase for Insulin-like Growth Factor-I Receptor with Distinct Roles from Mdm2 in Receptor Ubiquitination and Endocytosis." Canc. Res. 68: 5669-5677.

Tatematsu, K., et al. (2008) "Identification of Ubiquitin Ligase Activity of RBCK1 and Its Inhibition by Splice Variant RBCK2 and Protein Kinase C[beta]." J. Biol. Chem. 283: 11575-85.

Varfolomeev E., et al. (2008) "c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor [alpha](TNF[alpha])-induced NF-κB Activation." J. Biol. Chem. 283(36): 24295-24299.

Winter, M., et al. (2008) "Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.” Nature cell biology 10(7): 812–824.

Yang Z., et al. (2008) "Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication." J. Virol. 82: 3590-603.

Zhao, X., et al. (2008) "The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein.” Nature cell biology 10(6): 643–653.

Butler, M. P., et al. (2007). "Kinase active IRAKs promote polyubiquitination and degradation of the Pellino family: Direct evidence for Pellino proteins being E3 ubiquitin ligases." J. Biol. Chem. 282:29729-29737.

Dul, B. E. and N. C. Walworth (2007). "The Plant Homeodomain Fingers of Fission Yeast Msc1 Exhibit E3 Ubiquitin Ligase Activity." J. Biol. Chem. 282(25): 18397-18406.

Hong, K. U., et al. (2007). "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis." Mol. Cell. Biol. 27(10): 3667-3681.

Joch, M., et al. (2007). "Parkin-mediated Mono-ubiquitination of the PDZ Protein PICK1 Regulates the Activity of Acid-sensing Ion Channels." Mol. Biol. Cell 18(8): 3105-3118.

Kong, H. J., et al. (2007). "Cutting Edge: Autoantigen Ro52 Is an Interferon Inducible E3 Ligase That Ubiquitinates IRF-8 and Enhances Cytokine Expression in Macrophages." J. Immunol. 179(1): 26-30.

Lu, Z., et al. (2007). "Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction." J. Cell Biol. 177(6): 1077-1081.

Morokuma, Y., et al. (2007). "MARCH-XI, a Novel Transmembrane Ubiquitin Ligase Implicated in Ubiquitin-dependent Protein Sorting in Developing Spermatids." J. Biol. Chem. 282(34): 24806-24815.

Olzmann, J.A., et al. (2007) "Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6." J. Cell Biol. 178(6): 1025-1038.

Sun, Z., et al. (2007). "Keap1 Controls Post-Induction Repression of the Nrf2-Mediated Antioxidant Response by Escorting Nuclear Export of Nrf2." Mol. Cell. Biol.: 27(18):6334-6349.

Abramovitch, R. B., et al. (2006). "Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity." PNAS 103(8): 2851-2856.

Gurtan, A. M., et al. (2006) "The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly." J. Biol. Chem. 281(16): 10896-10905.

Ji, P., et al. (2006). "Skp2 Contains a Novel Cyclin A Binding Domain That Directly Protects Cyclin A from Inhibition by p27kip1." J. Biol. Chem. 281(33): 24058-24069.

Lo, S.-C. and M. Hannink (2006). "PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex." J. Biol. Chem.: 281:37893-37903.

Oh, R. S., et al. (2006) "Human Homologs of Ubc6p Ubiquitin-conjugating Enzyme and Phosphorylation of HsUbc6e in Response to Endoplasmic Reticulum Stress." J. Biol. Chem. 281(30): 21480-21490.

Wada K. And Kamitani T. (2006) "UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself." Biochem. Biophys. Res. Comm. 342(1): 253-258.

Yurchenko, V., et al. (2006). "SUMO Modification of Human XRCC4 Regulates Its Localization and Function in DNA Double-Strand Break Repair." Mol. Cell. Biol. 26(5): 1786-1794.

Bottomley M., et al. (2005) "NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1): Insights into Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (Apeced) Disease." J. Biol. Chem. 280(12): 11505-11512.

Furukawa, M. and Xiong Y. (2005) "BTB Protein Keap1 Targets Antioxidant Transcription Factor Nrf2 for Ubiquitination by the Cullin 3-Roc1 Ligase." Mol. Cell. Biol. 25(1): 162-171.

Gentry M. S., et al. (2005) "From The Cover: Insights into Lafora disease: Malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin." PNAS 102(24): 8501-8506.

Horn P. J., et al. (2005) "A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation." Genes & Dev. 19(14): 1705-1714.

Kaneko-Oshikawa C., et al. (2005) "Mammalian E4 Is Required for Cardiac Development and Maintenance of the Nervous System." Mol. Cell. Biol. 25(24): 10953-10964.

Kus B., et al. (2005) "A High Throughput Screen to Identify Substrates for the Ubiquitin Ligase Rsp5." J. Biol. Chem. 280(33): 29470-29478.

Schmidt A., et al. (2005) "Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity." Genes & Dev. 19(4): 502-513.

Stone S. L., et al. (2005) "Functional Analysis of the RING-Type Ubiquitin Ligase Family of Arabidopsis." Plant Physiology 137(1): 13-30.

Wang Z., et al. (2005) "RING-H2 Protein WSSV249 from White Spot Syndrome Virus Sequesters a Shrimp Ubiquitin-Conjugating Enzyme, PvUbc, for Viral Pathogenesis." J. Virol. 79(14): 8764-8772.

Yang J., et al. (2005) "Light Regulates COP1-Mediated Degradation of HFR1, a Transcription Factor Essential for Light Signaling in Arabidopsis." Plant Cell 17(3): 804-821.

Zhang D. D., et al. (2005) "Ubiquitination of Keap1, a BTB-Kelch Substrate Adaptor Protein for Cul3, Targets Keap1 for Degradation by a Proteasome-independent Pathway." J. Biol. Chem. 280(34): 30091-30099.

Adachi K., et al. (2004) "Ubiquitylation of Nascent Globin Chains in a Cell-free System." J. Biol. Chem. 279(40): 41767-41774.

Burstein E., et al. (2004) "A novel role for XIAP in copper homeostasis through regulation of MURR1." EMBO J. 23(1): 244-254.

Fotia A. B., et al. (2004) "Regulation of Neuronal Voltage-gated Sodium Channels by the Ubiquitin-Protein Ligases Nedd4 and Nedd4-2." J. Biol. Chem. 279(28): 28930-28935.

Mudgil Y., et al. (2004) "A Large Complement of the Predicted Arabidopsis ARM Repeat Proteins Are Members of the U-Box E3 Ubiquitin Ligase Family." Plant Physiology 134(1): 59-66.

Rajendra R., et al. (2004) "Topors Functions as an E3 Ubiquitin Ligase with Specific E2 Enzymes and Ubiquitinates p53." J. Biol. Chem. 279(35): 36440-36444.

Watanabe K., et al. (2004) "Rad18 guides pol[beta] to replication stalling sites through physical interaction and PCNA mono-ubiquitination." EMBO J. 23(19): 3886-3896.

Yanagawa Y., et al. (2004) " Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes. " Genes & Dev. 18(17): 2172-2181.

Yang Q.-H. and Du C. (2004) "Smac/DIABLO Selectively Reduces the Levels of c-IAP1 and c-IAP2 but Not That of XIAP and Livin in HeLa Cells." J. Biol. Chem. 279(17): 16963-16970.

Zhang D. D., et al. (2004) "Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex." Mol. Cell. Biol. 24(24): 10941-10953.

Hu S. and Yang X. (2003). "Cellular inhibitor of apoptosis1 and 2 are ubiquitin ligase for the apoptosis inducer Smac/DIABLO." J. Biol. Chem. 278(12): 10055-10060.