Product References

Boston Biochem has the industry's most referenced product range. Our products have been used in hundreds of UPP-related publications. Below is a select list of the most recent references. Products referenced in each article are listed below in red. Please inquire to request archives.

* Published online ahead of print

E1 Activating

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | E1

Zou, C., et al. (2011) “LPS Impairs Phospholipid Synthesis by Triggering [beta]-Transducin Repeat-containing Protein ([beta]-TrCP)-mediated Polyubiquitination and Degradation of the Surfactant Enzyme Acyl-CoA:Lysophosphatidylcholine Acyltransferase I (LPCAT1).”

21068446 | E1

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

21775430 | E1

Hyuk Lee, D., et al. (2011) “The Pepper E3 Ubiquitin Ligase RING1 Gene, CaRING1, Is Required for Cell Death and the Salicylic Acid-Dependent Defense Response.” Plant Physiology 156: 2011 - 2025.

21628629 | Yeast E1

Wu, K., et al. (2011) “Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1.” J. Biol. Chem. 286: 34060 - 34070.

21813641 | E1

Zhu, M., et al. (2011) “Pheromone- and RSP5-dependent Ubiquitination of the G Protein [beta] Subunit Ste4 in Yeast.” J. Biol. Chem. 286: 27147 - 27155.

21685393 | human E1-activating enzyme Uba1

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” 

21343341 | Ubiquitin E1 activation enzyme

Bocik, W., et al. (2011) “Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2G2.” The Journal of Biological Chemistry, 286: 3981-3991.

21098018 | E1

Bosanac, I., et al. (2011) “Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.” Journal of Mol. Bio.: doi:10.1016/j.jmb.2011.03.011."

21396940 | recombinant human E1

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | E1 enzyme

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | E1 enzyme

Cheng, P., et al. (2011) “Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development.” Neuron, 69: 231-243.

21262463 | All the enzymes used for ubiquitination assay

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

21768287 | UBE1

Bocik, W., et al. (2011) “Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2G2.” The Journal of Biological Chemistry, 286: 3981-3991.

21098018 | E1

Bosanac, I., et al. (2011) “Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.” Journal of Mol. Bio.: doi:10.1016/j.jmb.2011.03.011."

21396940 | recombinant human E1

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | E1 enzyme

Chang, C., et al (2011) “A Novel Cyclic AMP/Epac1/CaMKI Signaling Cascade Promotes GCM1 Desumoylation and Placental Cell Fusion.” Mol. Cell. Biol. 31: 3820 - 3831.

21791615 | recombinant SAE1/SAE2

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” 

21343341 | Ubiquitin E1 activation enzyme

Cheng, P., et al. (2011) “Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development.” Neuron, 69: 231-243.

21262463 | All the enzymes used for ubiquitination assay

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

21768287 | UBE1

Cui, Y., et al. (2011) "SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.” The EMBO Journal 30(13): 2675–2689.

21572392 | E1

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | E1

Hadian, K., et al. (2011) “NF-B Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-B Activation.” J. Biol. Chem. 286: 26107 - 26117.

21622571 | E1 enzyme UBE1

Hessa, T., et al. (2011) "Protein targeting and degradation are coupled for elimination of mislocalized proteins.” Nature 475(7356): 394–397.

21743475 | human E1 enzyme

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

E1

Inhibitors

Rinetti, G.V. and Schweizer, F. (2010) “Ubiquitination Acutely Regulates Presynaptic Neurotransmitter Release in Mammalian Neurons.” J. Neurosci. 30: 3157 - 3166.

20203175 | clasto-lactacystin [beta]-lactone

E2 Conjugating

Huang, H.S., et al. (2011) "Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.” Nature 481(7380): 185–189.

22190039 | UBCH7

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | E2

Gannavaram, S., et al. (2011) “Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani.” PLoS one 6: e16156. doi:10.1371/journal.pone.0016156.

21264253 | Human recombinant Uba5

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

21775430 | E2

Zhu, F., et al. (2011) “Phosphorylation of H2AX at Ser139 and a New Phosphorylation Site Ser16 by RSK2 Decreases H2AX Ubiquitination and Inhibits Cell Transformation.” Cancer Research, 71: 393.

21224359 | recombinant UbcH5a

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | UbcH7

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

21768287 | UBCH10, UBCH5

Galisson, F., et al. (2011) “A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells.” Molecular and Cellular Proteomics, 10: M110.004796.

21098080 | hUbC9, GST- RanGAP fragment 418–587

Hadian, K., et al. (2011) “NF-B Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-B Activation.” J. Biol. Chem. 286: 26107 - 26117.

21622571 | Lys-63 specific E2 complex UbcH13/Uev1a

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

21258371 | His–Ubc H3, His–Ubc H5

Jones, J., et al. (2011) “The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3.” Immunology Letters, 2: 156-162.

1256161 | UbcH2

Kim, J., et al (2011) “Role of TRIM5[alpha] RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus.” J. Virol. 85: 8116 - 8132.

21680520 | UbcH5a

Lin, D., et al. (2011) “Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.” The Journal of Biological Chemistry, 286: 441-449.

20980253 | E2 enzymes

Lu, J., et al. (2011) “RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation.” J. Biol. Chem. 286: 24426 - 24433.

21610068 | UbcH5b

Lu, K., et al. (2011) “Pivotal role of the SMURF1 C2 domain in substrate selection.” The Journal of Biological Chemistry: doi:10.1074/jbc.M110.211979.

21402695 | UbcH5c (E2)

Mao, X., et al. (2011) “COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding.” J. Biol. Chem. 286: 32355 - 32365.

21778237 | human His6-E1 (Uba1), UbcH10, UbcH3, UbcH5a, UbcH5b, UbcH5c, UbcH7

Meisenberg, C., et al. (2011) “Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.” Nucleic Acids Res. 10.1093/nar/gkr744.

21933813 | E2

Nagel, C., et al. (2011) “Herpes Simplex Virus Immediate-Early Protein ICP0 Is Targeted by SIAH-1 for Proteasomal Degradation.” J. Virol. 85: 7644 - 7657.

21632771 | ubiquitin-conjugating enzyme UbcH5b

Shibata, E., et al. (2011) “Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex.” Mol. Cell. Biol. 31: 3136 - 3145.

21628527 | recombinant UBCH5C

Sung, C.K., et al. (2011) “Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150Sal2.” The FASEB Journal fj.10-173674; published ahead of print January 12, 2011,doi:10.1096/fj.10-173674.

21228219 | UbcH5c (E2-627)

Wang, Y., et al. (2011) “The ubiquitin-dependent proteasomal degradation (UPD) of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and Ubiquitination.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.176685 .

21209460 | UbcH5a

Wu, K., et al. (2011) “Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1.” J. Biol. Chem. 286: 34060 - 34070

21813641 | APP-BP, Uba3, Ubc12, UbcH5c

Zhang, N., et al. (2011) “Ubiquitin Chain Trimming Recycles the Substrate Binding Sites of the 26 S Proteasome and Promotes Degradation of Lysine 48-linked Polyubiquitin Conjugates.” J. Biol. Chem. 286: 25540 - 25546.

21632534 | UbcH10

Zhao, R., et al. (2011) “Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.” JCI, 121: 851-865.

21317535 | E2 (E2-622)

Cui, Y., et al. (2011) "SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.” The EMBO Journal 30(13): 2675–2689.

21572392 | UbcH5c

E3 Ligase

Kalia, L.V., et al. (2011) “Ubiquitinylation of [alpha]-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5).” PloS one, 6: e14695. doi:10.1371/journal.pone.0014695 .

21358815 | HDM2, MuRF1

Bosanac, I., et al. (2011) “Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.” Journal of Mol. Bio.: doi:10.1016/j.jmb.2011.03.011.* .

21396940 | MURF1

Shin, J., et al. (2011) “PARIS (ZNF746) Repression of PGC-1[alpha] Contributes to Neurodegeneration in Parkinson's Disease.” Cell, 144: 689-702.

21376232 | His-Parkin

Jin, X, et al. (2010) “An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-B-inducing Kinase via Lys63-linked Ubiquitination.” J. Biol. Chem. 285: 30539-30547.

20682767 | Lys63-only ubiquitin

Kaneko, M., et al. (2010) “Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-[beta] Generation.” J. Neurosci., 3924 - 3932.

20237263 | RP-HRD1 (E3)

Chymkowitch, P., et al. (2010) "The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.” The EMBO Journal 30(3): 468–479.

21157430 | MDM2

Fu, W., et al. (2009) "MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation." J. Biol. Chem. 284: 13987-14000.

19321440 | MDM2

Siepe, D. and Jentsch, S. (2009) "Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation.” Nature Cell Biology 11(8): 967–972.

19597489 | recombinant E3 (His6-Mdm2)

Newton, K., et al. (2008) "Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies.” Cell 134(4): 668–678.

18724939 | MuRF1 autoubiquitination reactions

Hrecka, K., M. Gierszewska, et al. (2007). "Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle." PNAS 104(28): 11778-11783.

17609381

Fortier, J. M. and J. Kornbluth (2006). "NK Lytic-Associated Molecule, Involved in NK Cytotoxic Function, Is an E3 Ligase." J. Immunol. 176(11): 6454-6463.

Polyclonal UbcH8 Ab

Dai, M.-S., D. et al. (2006). "Regulation of the MDM2-p53 Pathway by Ribosomal Protein L11 Involves a Post-ubiquitination Mechanism." J. Biol. Chem. 281(34): 24304-24313.

16803902 | purified human recombinant E2 (UbcH5a)

Burstein E., et al. (2004) "A novel role for XIAP in copper homeostasis through regulation of MURR1." EMBO J. 23(1): 244-254.

14685266 | E3

Deconjugating

Capodagli, G., et al. (2011) “Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin.” Journal of Virology, 85: 3621-3630.

21228232 | Ub-AMC

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” 

21343341 | ubiquitin aldehyde

James, T., et al. (2011) “Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.” PNAS, 108: 2222-2227.

21245344 | ISG15–AMC

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | Wild-type ubiquitin

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | ubiquitin aldehyde

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

21768287 | HA-UbVS probe

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

21258371 | ubiquitin aldehyde

Lu, J., et al. (2011) “RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation.” J. Biol. Chem. 286: 24426 - 24433.

21610068 | HA-ubiquitin

Lu, K., et al. (2011) “Pivotal role of the SMURF1 C2 domain in substrate selection.” The Journal of Biological Chemistry: doi:10.1074/jbc.M110.211979.

21402695 | HA–ubiquitin

Stringer, D. and Piper, R. (2011) “A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT Ubiquitination.” JCB, 192: 229-242.

21242292 | Ub-Aldehyde

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

21807946 | ubiquitin-aldehyde

Wickliffe, K., et al. (2011) “The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2.” Cell, 144: 769-781.

21376237 | wild-type ubiquitin

Yang, K., et al. (2011) “Regulation of the Fanconi anemia pathway by a SUMO-like delivery network.” Genes & Dev. 25: 1847 - 1858.

21896657 | Ub-AMC

Mansfeld, J., et al. (2011) "APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.” Nature cell biology 13(10): 1234–1243.

21926987 | anti-UbcH10

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Ub-AMC

Jones, M.J.K., et al. (2011) "Dysregulation of DNA polymerase [kappa] recruitment to replication forks results in genomic instability.” The EMBO Journal. 31(4):908-18.

recombinant USP2 catalytic domain (DUB-CD)

Artavanis-Tsakonas, K., et al. (2010) “Characterization and Structural Studies of the Plasmodium falciparum Ubiquitin and Nedd8 Hydrolase UCHL3.” J. Biol. Chem. 285: 6857 - 6866.

20042598 | Nedd8-AMC

Clapp, K. M., et al. (2010) “C331A Mutant of Neuronal Nitric-oxide Synthase Is Labilized for Hsp70/CHIP (C Terminus of HSC70-interacting Protein)-dependent Ubiquitination.” J. Biol. Chem. 285: 33642-33651.

20729196 | ubiquitin aldehyde

de Thonel, A., et al. (2010) “HSP27 controls GATA-1 protein level during erythroid cell differentiation.” Blood116: 85 - 96.

20410505 | ubiquitin-aldehyde

Geng, L., et al. (2010) “RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network.” J. Cell Biol. 191: 249-257.

20937699 | human recombinant UBE2T

Guo, Y., et al. (2010) “Blockade of the Ubiquitin Protease UBP43 Destabilizes Transcription Factor PML/RAR and Inhibits the Growth of Acute Promyelocytic Leukemia.” Cancer Res. 70: 9875-9885.

20935222 | HA-ISG15-vinylmethyl ester (HA-ISG15-VME)

Hallows, K.R., et al. (2010) “Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel.” J. Biol. Chem. 285: 21671 - 21678.

20466724 | HA-tagged ubiquitin

Kops, G., et al. (2010) "APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome." J. Cell Sci. 123: 1623 - 1633.

20392738 | HA-ubiquitin

Sánchez Manchinelly, S.A. (2010) “Mitotic Down-regulation of p190RhoGAP Is Required for the Successful Completion of Cytokinesis.” J. Biol. Chem. 285: 26923 - 26932.

20534586 | ubiquitin aldehyde

An, J.Y., et al. (2010) “UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination.” PNAS 107: 1912 - 1917.

20080676 | Ub tagged with ha

Proteasome

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

21364033 | MG-132

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

21364033 | MG-132

Bulut, G., et al. (2011) “Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor.” The Journal of Biological Chemistry, 286: 6449-6457.

21183685 | Lactacystin

Chen, L., et al. (2011) “Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus.” The Journal of Biological Chemistry, 286: 3104-3118.

21075847 | LLVY-AMC

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Z-LRGG-AMC

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | MG-132

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | MG-132

Dammer, E., et al. (2011) “Polyubiquitin linkage profiles in three models of proteolytic stress suggest etiology of Alzheimer disease.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.149633.

21278249 | epoxomicin

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | lactacystin

Emanuele, M.J., et al. (2011) "Global Identification of Modular Cullin-RING Ligase Substrates.” Cell 147(2): 459–474.

21963094 | MG132

Foley, E.A., et al. (2011) "Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.” Nature Cell Biology 13(10): 1265–1271.

21874008 | MG132

Huang, Y., et al. (2011) “UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation.” Mol. Bio. of the Cell: doi:10.1091/mbc.E10-10-0827.

21307340 | MG132

Jo, Y., et al. (2011) “Membrane-associated Ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.211326.

21343306 | MG-132

Li, H., et al. (2011) "Regulation of NF-[kappa]B activity by competition between RelA acetylation and ubiquitination.” Oncogene. 31(5):611-23.

21706061 | MG-132

Mi, L., et al. (2011) “Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.” Carginogenesis, 32: 216-223.

21109604 | purified 20S proteasome extracted from rabbit erythrocytes

Obaidat, A., et al. (2011) “Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs.” Jour. of Pharm. and Exp. Therapeutics: doi:10.1124/jpet.110.177824.

21303921 | Suc-LLVY-AMC

Solis, M., et al. (2011) “RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I.” Journal of Virology, 85: 1224-1236.

21084468 | MG132

Sun, H., et al. (2011) “Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.” Blood, 117: 3151-3162.

21248063 | MG-132

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

21807946 | MG132

Lin, D., et al. (2011) “Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.” The Journal of Biological Chemistry, 286: 441-449.

20980253 | mutant Ubs

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.*.

21177809 | proteasome inhibitor MG132

Dasmahapatra, G., et al. (2010) "The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo." Blood. 115: 4478 - 4487.

20233973 | Suc-LLVY-7-amino-4-methylcoumarin

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.

21177809 | proteasome inhibitor MG132

Bauer, S., et al. (2010) “Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells.” Cancer Res. 70: 150 - 159.

20028860 | MG-132

Byun, H., et al. (2010) “Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function.” PNAS 107: 12287 - 12292.

20566871 | MG132

Inhibitor

Arastu-Kapur, S., et al. (2011) “Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events.” Clinical Cancer Research: doi: 10.1158/1078-0432.CCR-10-1950.

21364033 | MG-132

Bulut, G., et al. (2011) “Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor.” The Journal of Biological Chemistry, 286: 6449-6457.

21183685 | Lactacystin

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.

21343341 | ubiquitin aldehyde

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Ub-VS

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | MG-132, ubiquitin aldehyde

Dammer, E., et al. (2011) “Polyubiquitin linkage profiles in three models of proteolytic stress suggest etiology of Alzheimer disease.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.149633.

21278249 | MG‐132

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | MG132

Feltham, R., et al. (2011) “SMAC-mimetics activate the E3 ligase activity of cIAP1 by promoting RING dimerisation.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M111.222919.

21393245 | MG132

Foley, E.A., et al. (2011) "Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.” Nature Cell Biology 13(10): 1265–1271.

21874008 | MG132

Huang, L., et al. (2011) "Hydrophobicity as a driver of MHC class I antigen processing.” The EMBO Journal 30(8): 1634–1644.

21378750 | epoxomicin

Huang, Y., et al. (2011) “UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation.” Mol. Bio. of the Cell: doi:10.1091/mbc.E10-10-0827.

21307340 | MG132

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

21258371 | ubiquitin aldehyde

Jo, Y., et al. (2011) “Membrane-associated Ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase.” The Journal of Biological Chemistry: doi: 10.1074/jbc.M110.211326.

21343306 | MG-132

Li, H., et al. (2011) "Regulation of NF-[kappa]B activity by competition between RelA acetylation and ubiquitination.” Oncogene. 31(5):611-23.

21706061 | MG-132

Solis, M., et al. (2011) “RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I.” Journal of Virology, 85: 1224-1236.

21084468 | MG132

Stringer, D. and Piper, R. (2011) “A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT Ubiquitination.” JCB, 192: 229-242.

21242292 | Ub-Aldehyde

Sun, H., et al. (2011) “Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.” Blood, 117: 3151-3162.

21248063 | lactacystin

Tanioka, T., et al. (2011) “Inducible Nitric-oxide Synthase and Nitric Oxide Donor Decrease Insulin Receptor Substrate-2 Protein Expression by Promoting Proteasome-dependent Degradation in Pancreatic [beta]-Cells: INVOLVEMENT OF GLYCOGEN SYNTHASE KINASE-3[beta].” J.

21700708 | lactacystin

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

21807946 | MG132

Arnold, M. M. and Patton, J. T. (2010) “Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains.” J. Virol. 10.1128/JVI.01801-10.* 

21177809 | proteasome inhibitor MG132

Bauer, S., et al. (2010) “Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells.” Cancer Res. 70: 150 - 159.

20028860 | MG-262

Byun, H., et al. (2010) “Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function.” PNAS 107: 12287 - 12292.

20566871 | lactacystin

Chandra, A., et al. (2010) “Proteasome Assembly Influences Interaction with Ubiquitinated Proteins and Shuttle Factors.” J. Biol. Chem. 285: 8330 - 8339.

20061387 | Epoxomicin

Clapp, K. M., et al. (2010) “C331A Mutant of Neuronal Nitric-oxide Synthase Is Labilized for Hsp70/CHIP (C Terminus of HSC70-interacting Protein)-dependent Ubiquitination.” J. Biol. Chem. 285: 33642-33651.

20729196 | ubiquitin-activating enzyme (E1)

de Thonel, A., et al. (2010) “HSP27 controls GATA-1 protein level during erythroid cell differentiation.” Blood116: 85 - 96.

20410505 | Ubiquitin-Protein Conjugation Kit

Ubiquitin

Bhandari, D., et al. (2011) “Ubiquitination of mRNA cycling sequence binding protein from Leishmania donovani (LdCSBP) modulates the RNA endonuclease activity of its Smr domain.” FEBS Letters, 585: 809-813.

K48 linked His–Ub

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | mutant forms of ubiquitin, Wild-type ubiquitin

Capodagli, G., et al. (2011) “Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin.” Journal of Virology, 85: 3621-3630.

21228232 | tetra- and di-Ub linked by either K48 or K63 isopeptide bonds

Chen, B.B., et al (2011) “Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.” Molecular and Cellular Biology: doi:10.1128/MCB.00723-10.” .

21343341 | ubiquitin aldehyde

Chenon, M., et al. (2011) "A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.” The EMBO Journal 31(3): 741–753.

22117220 | Lys48-linked poly-Ub chain, Lys63-linked poly-Ub chain

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | myc-Ub, ubiquitin aldehyde

Cotto-Rios, X.M., et al. (2011) “APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.” J. Cell Biol. 194: 177 - 186.

21768287 | ubiquitin aldehyde, ubiquitin

Cui, Y., et al. (2011) "SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.” The EMBO Journal 30(13): 2675–2689.

21572392 | HA-ubiquitin

Durcan, T.M., et al. (2011). “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | K48-linked free Ub chain

Felle, M., et al. (2011). “The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.” Nucleic Acids Res. 10.1093/nar/gkr528.

21745816 | Flag-tagged ubiquitin

Fischer, E.S., et al. (2011). "The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation.” Cell 147(5): 1024–1039.

22118460 | hsUbiquitin, hsUbiquitin-K0

Gao, Y.F., et al. (2011). "Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability.” Nature Cell Biology 13(8): 924–933.

21743465 | ubiquitin

Hessa, T., et al. (2011) "Protein targeting and degradation are coupled for elimination of mislocalized proteins.” Nature 475(7356): 394–397.

21743475 | His-tagged ubiquitin

Hou, F., et al. (2011) "MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.” Cell 146(3): 448–461.

21782231 | K48-Ub4, K63-Ub4

Huang, H.S., et al. (2011) "Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.” Nature 481(7380): 185–189.

22190039 | ubiquitin

Huang, Z., et al. (2011) “Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells.” Nature Cell Biology, 13: 142-152.

21258371 | ubiquitin

Ikeda, F., et al. (2011) "SHARPIN forms a linear ubiquitin ligase complex regulating NF-[kappa] B activity and apoptosis.” Nature 471(7340): 637–641.

21455181 | ubiquitin

James, T., et al. (2011) “Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.” PNAS, 108: 2222-2227.

21245344 | Ub–AMC

Kassmeier, M.D., et al. (2011) "VprBP binds full-length RAG1 and is required for B-cell development and V (D) J recombination fidelity.” The EMBO Journal. 31(4):945-58.

22157821 | myc–Ub

Kim, J., et al (2011) “Role of TRIM5[alpha] RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus.” J. Virol. 85: 8116 - 8132.

21680520 | myc-ubiquitin

Kim, Y., et al (2011) “Mutations of the SLX4 gene in Fanconi anemia.” Nature Genetics, 43, 142-146.

21240275 | mono-Ub

Kuhlbrodt, K., et al. (2011) "The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis.” Nature cell biology 13(3): 273–281.

21317884 | K48-linked ubiquitin chains

LaLonde, D. and Bretscher, A. (2011) “The UBX Protein SAKS1 Negatively Regulates Endoplasmic Reticulum-associated Degradation and p97-dependent Degradation.” The Journal of Biological Chemistry, 286: 4892-4901.

21135095 | Lys-48-linked polyubiquitin chains

Li, C., et al. (2011) "Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1.” Oncogene 30(42): 4350–4364.

21577200 | ubiquitin

Lin, Y., et al. (2011) “The Defective Proteasome but Not Substrate Recognition Function Is Responsible for the Null Phenotypes of the Arabidopsis Proteasome Subunit RPN10.” PLANT CELL 23: 2754 - 2773.

21764993 | Lys-48–linked ubiquitin chains (Ub2-7), Lys-63–linked ubiquitin chains (Ub2-7)

SUMO

Chang, C., et al (2011) “A Novel Cyclic AMP/Epac1/CaMKI Signaling Cascade Promotes GCM1 Desumoylation and Placental Cell Fusion.” Mol. Cell. Biol. 31: 3820 - 3831.

21791615 | His-SUMO1

Chang, C., et al (2011) “A Novel Cyclic AMP/Epac1/CaMKI Signaling Cascade Promotes GCM1 Desumoylation and Placental Cell Fusion.” Mol. Cell. Biol. 31: 3820 - 3831.

21791615 | recombinant SAE1/SAE2

Galisson, F., et al. (2011) “A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells.” Molecular and Cellular Proteomics, 10: M110.004796.

21098080 | SASE1/SAE2 heterodimer

Wyatt, D., et al. (2011) “Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor Trafficking.” The Journal of Biological Chemistry, 286: 3884-3893.

21118812 | anti-SUMO-1 polyclonal antibody

Koike, A, et al. (2010) “Recruitment of Phosphorylated NPM1 to Sites of DNA Damage through RNF8-Dependent Ubiquitin Conjugates.” Cancer Res. 70: 6746 - 6756.

20713529 | SUMO polymers

Chu, Y. and Yang, X. (2010) "SUMO E3 ligase activity of TRIM proteins.” Oncogene 30(9): 1108–1116.

20972456 | SUMO E1, SUMO1, SUMO2

Shanks. J., et al. (2009) "Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages." Infect. Immun. 77 (4): 1636-1648.

19168747 | Di-SUMO-2, Di-SUMO-3

Zunino, R., et al.(2009) "Translocation of SenP5 from the Nucleoli to the Mitochondria Modulates DRP1-dependent Fission during Mitosis." J. Biol. Chem. 284: 17783-17795.

19411255 | His6-SUMO1, SUMO activating enzyme

MacPherson, M.J., et al. (2009) "The CTCF Insulator Protein Is Post-translationally Modified by SUMO." Mol. Cell. Biol. 29(3): 714-725.

19029252 | SUMO1, SUMO2, SUMO3

Dawlaly, M.M., et al. (2008) "Resolution of Sister Centromeres requires RanBP2-mediated SUMOylation of Topoisomerase II[alpha]." Cell 133: 103-115.

18394993 | SUMO1 conjugation kit

Lima, C.D. and Reverter, D. (2008) "Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7." J. Biol. Chem. 283 (46): 32045-32055.

18799455 | di-SUMO2, di-SUMO3, poly-SUMO2, poly-SUMO3

Benson, M. D., et al. (2007). "SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5." PNAS 104(6): 1805-1810.

17261810 | lactacystin

Chou, C.-C., et al. (2007). "SUMO modification regulates the DNA-binding activity of GCMa." J. Biol. Chem.: 282(37): 27239-27249.

17646165 | recombinant SAE1/SAE2

Catic A., et al. (2007) "Screen for ISG15-cross-reactive Deubiquitinases." PLoS ONE 2(7): E769.

17653289 | GST-SUMO1

Miller, S. L. H., et al. (2007). "Ubiquitin-interacting Motifs Inhibit Aggregation of PolyQ-expanded Huntingtin." J. Biol. Chem. 282(13): 10096-10103.

17276991 | SUMO-1

Rytkonen, A., et al. (2007) "SseL, a Salmonella deubiquitinase required for macrophage killing and virulence4." PNAS 104(9): 3502-3507.

SUMO-1-AMC

Avvakumov, G. V., et al. (2006). "Amino-terminal dimerization, NRDP1 (FLRF) - rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin specific protease 8 (USP8/UBPY)." J. Biol. Chem.281(49):38061-38070.

17035239 | SUMO-AMC

Yurchenko, V., et al. (2006). "SUMO Modification of Human XRCC4 Regulates Its Localization and Function in DNA Double-Strand Break Repair." Mol. Cell. Biol. 26(5): 1786-1794.

16478998 | SUMO1

Muromoto, R., et al. (2006). "Sumoylation of Daxx Regulates IFN-Induced Growth Suppression of B Lymphocytes and the Hormone Receptor-Mediated Transactivation." J. Immunol. 177(2): 1160-1170.

16818774 | anti-SUMO1

Zhou H., et al. (2005) "Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation." J. Exp. Med. 202(10): 1327-1332.

16301742 | Sumo-AMC

NEDD8

Capodagli, G., et al. (2011) “Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin.” Journal of Virology, 85: 3621-3630.

21228232 | NEDD8-AMC

Wu, K., et al. (2011) “Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1.” J. Biol. Chem. 286: 34060 - 34070.

21813641 | Nedd8, PK-Nedd8

Hosp, J., et al. (2011) "A tobacco homolog of DCN1 is involved in cellular reprogramming and in developmental transitions.” doi:10101/npre.2011.5728.1

10101 | NEDD8- agarose

Artavanis-Tsakonas, K., et al. (2010) “Characterization and Structural Studies of the Plasmodium falciparum Ubiquitin and Nedd8 Hydrolase UCHL3.” J. Biol. Chem. 285: 6857 - 6866.

20042598 | NedP1

Choi, Y. et al. (2010) "The Human Cdc34 Carboxyl Terminus Contains a Non-covalent Ubiquitin Binding Activity That Contributes to SCF-dependent Ubiquitination." J. Biol. Chem. 285: 17754 - 17762.

20353940 | E1 enzyme for Nedd8 (APP-BP1/Uba3)

Gastaldello, S., et al. (2010) "A deneddylase encoded by Epstein–Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases.” Nature cell biology 12(4): 351–361.

20190741 | NEDD8-VS functional probe

Cooper, E.M., et al. (2009) "K63-specific deubuiquitination by two JAMM/MPN+ complexes:BRISC-associated Brcc-36 and proteasomal Poh1." EMBO J. 28(6) 621-631 .

Nedd8

Kim, A.Y., et al. (2008) “SCCRO (DCUN1D1) Is an Essential Component of the E3 Complex for Neddylation.” J. Biol. Chem. 283(48): 33211-33220.

18826954 | NEDD8

Heuzé, M.L., et al. (2008) "ASB2 targets filamins A and B to proteasomal degradation." Blood 112(13): 5130-5140.

18799729 | NEDD8

Miller, S. L. H., et al. (2007). "Ubiquitin-interacting Motifs Inhibit Aggregation of PolyQ-expanded Huntingtin." J. Biol. Chem. 282(13): 10096-10103.

17276991 | His-tagged NEDD8

Avvakumov, G. V., et al. (2006). "Amino-terminal dimerization, NRDP1 (FLRF) - rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin specific protease 8 (USP8/UBPY)." J. Biol. Chem.281(49):38061-38070.

17035239 | NEDD8-AMC

Oved, S., Y. Mosesson, et al. (2006). "Conjugation to Nedd8 Instigates Ubiquitylation and Down-regulation of Activated Receptor Tyrosine Kinases." J. Biol. Chem. 281(31): 21640-21651.

16735510 | anti-Nedd8, polyclonal

ISG15

Capodagli, G., et al. (2011) “Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin.” Journal of Virology, 85: 3621-3630.

21228232 | ISG15-AMC

James, T., et al. (2011) “Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.” PNAS, 108: 2222-2227.

21245344 | ISG15–AMC

Malakhova O.A. and Zhang D-E. (2008) "ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response." J. Biol. Chem. 283: 8783-8787.

18287095 | ISG15

Ratia, K, et al. (2008). "A non-covalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication." PNAS 105 (42): 16119-16124 .

18852458 | ISG15-AMC

Catic A., et al. (2007) "Screen for ISG15-cross-reactive Deubiquitinases." PLoS ONE 2(7): E769.

17653289 | ISG15

UFM1

Bacik, J., et al. (2010) “Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME.” J. Biol. Chem. 285: 20273 - 20280.

20368332 | UFM1

Autophagy

Havens, C. G., et al. (2006) "Regulation of Late G1/S Phase Transition and APCCdh1 by Reactive Oxygen Species." Mol. Cell. Biol. 26(12): 4701-4711.

16738333

Antibodies

Song, M., et al. (2011) “Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner.” Cell, 144: 187-199.

21241890 | Anti-UbcH10, anti-UbcH5, Anti-UbcH10 (A-650), (A-615)

Wang, H., et al. (2011) “CCI-779 Inhibits Cell-Cycle G2–M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability.” Cancer Res. 71: 4866 - 4876.

21593191 | anti-UBE2C

Chen, A., et al. (2011) “Enzyme E2 from Chinese White Shrimp Inhibits Replication of White Spot Syndrome Virus and Ubiquitinates Its RING Domain Proteins.” J. Virol. 85: 8069 - 8079.

21680526 | anti-ubiquitin / A-100

Chen, L., et al. (2011) “Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus.” The Journal of Biological Chemistry, 286: 3104-3118.

21075847 | Anti-His6 monoclonal antibody

Rakovic, A., et al. (2011) “Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts.” PLoS one, 6: e16746. doi:10.1371/journal.pone.0016746.

21408142 | anti-ubiquitin

Wyatt, D., et al. (2011) “Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor Trafficking.” The Journal of Biological Chemistry, 286: 3884-3893.

21118812 | anti-Ubc9 polyclonal antibody

Kaiser, S.E., et al. (2011) "Protein standard absolute quantification (PSAQ) "method for the measurement of cellular ubiquitin pools.” Nature methods 8(8): 691–696.

Ubiquitin antibody (A-100)

Kaiser, S.E., et al. (2011) "Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools.” Nature methods 8(8): 691–696.

21743460 | Ubiquitin antibody (A-100)

Mansfeld, J., et al. (2011) "APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.” Nature cell biology 13(10): 1234–1243.

21926987 | anti-UbcH10

Bacik, J., et al. (2010) “Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME.” J. Biol. Chem. 285: 20273 - 20280.

20368332 | anti-UFM1 primary rabbit polyclonal antibody

Kavazis, A. N., et al. (2010) “Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72.” Am. J. Physiol. Heart Circ. Physiol. 299: H1515-H1524.

20833957 | ubiquitin-protein conjugates

Tang, W., et al. (2010) “Emi2-mediated Inhibition of E2-substrate Ubiquitin Transfer by the Anaphase-promoting Complex/Cyclosome through a D-Box–independent Mechanism.” Mol. Biol. Cell 21: 2589 - 2597.

20534816 | anti UbcH10

Kumar, B., et al. (2010) “The C Terminus of Rpt3, an ATPase Subunit of PA700 (19 S) Regulatory Complex, Is Essential for 26 S Proteasome Assembly but Not for Activation.” J. Biol. Chem. 285: 39523-39535.

20937828 | anti-Rpt3

Liang, J., et al. (2010) “MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-B signaling.” J. Exp. Med. 207: 2959-2973.

21115689 | anti-ubiquitin

Van Ree, J., et al. (2010) “Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.” J. Cell Biol. 188: 83 - 100.

20065091 | rabbit anti-UbcH10

Vina-Vilaseca, A. and Sorkin, A. (2010) “Lysine 63-linked Polyubiquitination of the Dopamine Transporter Requires WW3 and WW4 Domains of Nedd4-2 and UBE2D Ubiquitin-conjugating Enzymes.” J. Biol. Chem. 285: 7645 - 7656.

20051513 | Affinity purified rabbit polyclonal anti-UBE2L3

Bianchi, G., et al. (2009) "The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition." Blood 113: 3040-3049.

19164601 | rabbit anti-X, rabbit anti-Y

Chen, A., et al. (2009) “The HECT-Type E3 Ubiquitin Ligase AIP2 Inhibits Activation-Induced T-Cell Death by Catalyzing EGR2 Ubiquitination.” Mol. Cell. Biol. 29: 5348 - 5356.

19651900 | anti-ubiquitin antibody

Kadara, H., et al. (2009) “Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System.” Cancer Prevention Research 2: 702 - 711.

19638491 | purified primary rabbit polyclonal anti-human UBE2C/UBCH10 antibody

Williamson, A., et al. (2009) “Identification of a physiological E2 module for the human anaphase-promoting complex.” PNAS 106: 18213 - 18218.

19822757 | anti-UbcH10

Bruce, S.R., et al (2009) "Respiratory Syncytial Virus (RSV) Infection Alters Surfactant Protein-A (SP-A) Expression in Human Pulmonary Epithelial Cells by Reducing Translation Efficiency." Am J Physiol Lung Cell Mol Physiol: 90507.2008.

19525387 | rabbit anti-human ubiquitin antibody

Meyer-Schaller, N., et al. (2009) “The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.” PNAS 106: 12365 - 12370.

19617556 | hUbc12 / A-655

Whitcomb, E.A., et al. (2009) "Novel Control of S Phase of the Cell Cycle by Ubiquitin-conjugating Enzyme H7." Mol. Biol. Cell 20(1): 1-9.

18946090 | anti-Ubc2, anti-UbcH10, anti-UbcH7 polyclonal

Page, E.L., et al. (2008) "Hypoxia-inducible Factor- [alpha] Stabilization in Non-hypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion." Mol. Biol. Cell 19: 86-94.

17942596 | Anti-ubiquitin

Liu, J., et al. (2008) "A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome." Am. J. Physiol. Heart.Circ. Physiol. 295(6): H2541-H2550.

18978187 | anti-COOH-terminal of heat shock protein cognate 70-interacting protein

Kits

Hodson, C., et al. (2011) “Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway.” J. Biol. Chem. 286: 32628 - 32637.

21775430 | His-UbcH7

Sung, C.K., et al. (2011) “Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150Sal2.” The FASEB Journal fj.10-173674; published ahead of print January 12, 2011,doi:10.1096/fj.10-173674.

21228219 | ubiquitin conjugation reaction buffer kit (SK-10)

Dolan, P.J. and Johnson, G. (2010) “A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway.” J. Biol. Chem. 285: 21978 - 21987.

20466727 | UbcH5b

Cohen, S., et al. (2009) "During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation." J. Cell Biol. 185: 1083-1095.

19506036 | UbcH13, Uev1 E2-conjugating enzyme

Pacheco, C.D., et al. (2009) "Tau deletion exacerbates the phenotype of Niemann–Pick type C mice and implicates autophagy in pathogenesis." Hum. Mol. Genet. 18(5): 956-965.

19074461 | 20S Proteasome Assay Kit, SDS-Activation Format

Sun, L., et al. (2009) “JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.” PNAS 106: 10195-10200.

ubiquitin-protein conjugation kit

Stanisic, V., et al (2009) "OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER)a and Affects ERa Transcriptional Activity." J. Biol. Chem. 284: 16135-16145.

19383985 | ubiquitination kit, K-960

Marfella, R., et al. (2008) "Proteasome Activity as a Target of Hormone Replacement Therapy-Dependent Plaque Stabilization in Postmenopausal Women." Hypertension 51: 1135-41.

proteasome 20S SDS activation kit

Marfella, R., et al. (2008) "Effects of Ubiquitin-Proteasome System Deregulation on the Vascular Senescence and Atherosclerosis Process in Elderly Patients." J. Gerontol. A Biol. Sci. Med. Sci. 63: 200-3.

sodium dodecyl sulfate [SDS]-activation kit

Marfella, R., et al. (2007). "Morning Blood Pressure Surge as a Destabilizing Factor of Atherosclerotic Plaque: Role of Ubiquitin-Proteasome Activity." Hypertension 49(4): 784-791.

proteasome-20S SDS-activation kit

Esposito, K., et al. (2006). "Rosiglitazone Cools Down Inflammation in the Metabolic Syndrome." Arterioscler. Thromb. Vasc. Biol. 26(6): 1413-1414.

16709957 | SDS-activation kit

Samuel, T., et al. (2006). "Distinct BIR Domains of cIAP1 Mediate Binding to and Ubiquitination of Tumor Necrosis Factor Receptor-associated Factor 2 and Second Mitochondrial Activator of Caspases." J. Biol. Chem. 281(2): 1080-1090.

16282325 | ubiquitin-protein conjugation kit

Marfella, R., et al. (2006). "The Ubiquitin-Proteasome System and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Rosiglitazone Treatment." Diabetes 55(3): 622-632.

16505224 | proteasome 20S SDS activation kit

Gurova K. V., et al. (2005) "Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors." PNAS 102(48): 17448-17453.

16287968 | kit for assaying proteasomal activity

Buffers, Solutions, Standards

Li, C., et al. (2011) "Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1.” Oncogene 30(42): 4350–4364.

21577200 | ATP

Zhang, X., et al. (2011) "USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1.” The EMBO Journal 30(11): 2177–2189.

21522127 | in vitro ubiquitination reaction buffer / Mg-ATP / stop buffer

James, T., et al. (2011) “Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.” PNAS, 108: 2222-2227.

21245344 | AMC standard

Zhu, F., et al. (2011) “Phosphorylation of H2AX at Ser139 and a New Phosphorylation Site Ser16 by RSK2 Decreases H2AX Ubiquitination and Inhibits Cell Transformation.” Cancer Research, 71: 393.

21224359 | energy regeneration solution (ERS) buffer

Cao, X., et al. (2011) “WW Domain-containing E3 Ubiquitin Protein Ligase 1 (WWP1) Delays Cellular Senescence by Promoting p27 Kip1 Degradation in Human Diploid Fibroblasts.” J. Biol. Chem. 286: 33447 - 33456.

21795702 | reaction buffer

Cosper, P. and Leinwand, L. (2011) “Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner.” Cancer Research, 71: 1710.

21163868 | Energy Regeneration Solution

Galisson, F., et al. (2011) “A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells.” Molecular and Cellular Proteomics, 10: M110.004796.

21098080 | Mg-ATP

Kim, J., et al (2011) “Role of TRIM5[alpha] RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus.” J. Virol. 85: 8116 - 8132.

21680520 | ATP / Energy regeneration system

Mao, X., et al. (2011) “COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding.” J. Biol. Chem. 286: 32355 - 32365.

21778237 | ATP regenerating buffer

Scortegagna, M., et al. (2011) “USP13 Enzyme Regulates Siah2 Ligase Stability and Activity via Noncatalytic Ubiquitin-binding Domains.” J. Biol. Chem. 286: 27333 - 27341.

21659512 | ATP

Uchida, S., et al. (2011) “SCF[beta]TrCP mediates stress-activated MAPK-induced Cdc25B degradation.” J. Cell Sci. 124: 2816 - 2825.

21807946 | ATP-regenerating system

Cui, Y., et al. (2011) "SCFFBXL15 regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.” The EMBO Journal 30(13): 2675–2689.

21572392 | ubiquitination assay buffer

Gerlach, B., et al. (2011) "Linear ubiquitination prevents inflammation and regulates immune signalling.” Nature 471(7340): 591–596.

ERS (energy regeneration system?)

Kassmeier, M.D., et al. (2011) "VprBP binds full-length RAG1 and is required for B-cell development and V (D) J recombination fidelity.” The EMBO Journal. 31(4):945-58.

reconjugation buffer

Tang, L.Y., et al. (2011) "Ablation of Smurf2 reveals an inhibition in TGF-[beta] signalling through multiple mono-ubiquitination of Smad3.” The EMBO Journal. 30(23):4777-89.

22045334 | ATP

Banerjee, S., et al. (2010) “Modulation of SCF[beta]-TrCP-dependent IB Ubiquitination by Hydrogen Peroxide.” J. Biol. Chem. 285: 2665 - 2675.

19933270 | Mg-ATP

Ensminger, A. and Isberg, R. (2010) “E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.” Infect. Immun., 78: 3905 - 3919.

20547746 | Energy regenerating solution

Hallows, K.R., et al. (2010) “Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel.” J. Biol. Chem. 285: 21671 - 21678.

20466724 | ATP

Sánchez Manchinelly, S.A. (2010) “Mitotic Down-regulation of p190RhoGAP Is Required for the Successful Completion of Cytokinesis.” J. Biol. Chem. 285: 26923 - 26932.

20534586 | Energy-Regenerating System

Song, I. Y., et al. (2010) “Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway.” J. Biol. Chem. 285: 31525-31536.

20675655 | ATP-regenerating system

Chu, Y. and Yang, X. (2010) "SUMO E3 ligase activity of TRIM proteins.” Oncogene 30(9): 1108–1116.

20972456 | ATP

Fujita, K., et al. (2010) "Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.” Nature cell biology 12(12): 1205–1212.

21057505 | energy solution / stop buffer

Liu, J. and Ma, J. (2010) "Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos.” Nature cell biology 13(1): 22–29.

21170036 | Mg–ATP

Burns, K.E., et al. (2009) "Proteasomal Protein Degradation in Mycobacteria Is Dependent upon a Prokaryotic Ubiquitin-like Protein." J. Biol. Chem. 284(5): 3069-3075.

19028679 | energy regeneration solution

Christopher, B., et al. (2009) “The EBV Deubiquitinating Enzyme, BPLF1, Reduces EBV Ribonucleotide Reductase Activity.” J. Virol. JVI.02195-08v1 .

19244336 | reaction mixture buffer (50 mM Tris, pH 7.5, 2 mM Mg-ATP)

Substrate Proteins

Galisson, F., et al. (2011) “A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells.” Molecular and Cellular Proteomics, 10: M110.004796.

21098080 | E2-25K

Wu, T., et al. (2010) “UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex.” PNAS 107: 1355 - 1360.

20080579 | E2-25K

Kim, H.T., et al. (2009) "S5a promotes protein degradation by blocking synthesis of non-degradable forked ubiquitin chains." EMBO J. 28: 1867-1877.

Gho, A.M., et al. (2008). "Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins." BMC Biochem. 9:4.

18234089 | E2-25K

Yamada, M., J. Ohnishi, et al. (2006). "NARF, an emo-like Kinase (NLK)-associated Ring Finger Protein Regulates the Ubiquitylation and Degradation of T Cell Factor/Lymphoid Enhancer Factor (TCF/LEF)." J. Biol. Chem. 281(30): 20749-20760.

16714285 | E2-25K

Affinity Matrices

Durcan, T.M., et al. (2011) “The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.” Human Molecular Genetics, 20: 141-154.

20940148 | His-ataxin-3 (14Q)

Gerlach, B., et al. (2011) "Linear ubiquitination prevents inflammation and regulates immune signalling.” Nature 471(7340): 591–596.

21455173 | agarose beads coupled to ubiquitin

LaLonde, D. and Bretscher, A. (2011) “The UBX Protein SAKS1 Negatively Regulates Endoplasmic Reticulum-associated Degradation and p97-dependent Degradation.” The Journal of Biological Chemistry, 286: 4892-4901.

21135095 | His6-tagged Ataxin-3

Sun, H., et al. (2011) “Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.” Blood, 117: 3151-3162.

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. | ataxin-agarose beads, Rap80-agarose beads

Feng, L., et al. (2010) “The Lys63-specific Deubiquitinating Enzyme BRCC36 Is Regulated by Two Scaffold Proteins Localizing in Different Subcellular Compartments.” J. Biol. Chem. 285: 30982-30988.

20656690 | RAP80 UIM-agarose beads

Liang, J., et al. (2010) “MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-B signaling.” J. Exp. Med. 207: 2959-2973.

21115689 | ubiquitin-agarose

De Schutter, J., et al. (2009) “SHIP2 (SH2 Domain-containing Inositol Phosphatase 2) SH2 Domain Negatively Controls SHIP2 Monoubiquitination in Response to Epidermal Growth Factor.” J. Biol. Chem. 284: 36062 - 36076.

19880507 | ubiquitin-agarose beads

Lis, E. T. and F. E. Romesberg (2006). "Role of Doa1 in the Saccharomyces cerevisiae DNA Damage Response." Mol. Cell. Biol. 26(11): 4122-4133.

16705165 | ubiquitin agarose

Kowanetz K., et al. (2004) "Suppressors of T-cell Receptor Signaling Sts-1 and Sts-2 Bind to Cbl and Inhibit Endocytosis of Receptor Tyrosine Kinases." J. Biol. Chem. 279(31): 32786-32795.

15159412 | Ub-Agarose

Fractions

Chaugule, V.K., et al. (2011) "Autoregulation of Parkin activity through its ubiquitin-like domain.” The EMBO Journal 30(14): 2853–2867.

21694720 | HeLa S100 fraction

Arun, P., et al. (2011) “Senescence Marker Protein 30 (SMP30) Expression in Eukaryotic Cells: Existence of Multiple Species and Membrane Localization.” PLoS one, 6: e16545. doi:10.1371/journal.pone.0016545.

21347421 | S-100 Hela degradation mixture

Zhu, F., et al. (2011) “Phosphorylation of H2AX at Ser139 and a New Phosphorylation Site Ser16 by RSK2 Decreases H2AX Ubiquitination and Inhibits Cell Transformation.” Cancer Research, 71: 393.

21224359 | Fraction II (FII)-HeLa

Bhandari, D., et al. (2011) “Ubiquitination of mRNA cycling sequence binding protein from Leishmania donovani (LdCSBP) modulates the RNA endonuclease activity of its Smr domain.” FEBS Letters, 585: 809-813.

S-100 HeLa conjugation kit

Burnett, B.G., et al. (2009) "Regulation of SMN Protein Stability." Mol. Cell. Biol. 29: 1107-1115.

19103745 | ubiquitin conjugation enzyme fraction

Marteijn, J., et al. (2009) "The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.” Leukemia 23(8): 1480–1489.

19340006 | reticulocyte fraction IIA

Wang, X., et al. (2009) “Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.” J. Cell Biol. 187: 655 - 668.

19951915 | FII from rabbit reticulocyte extract

Chiang M-H., et al. (2008) "Ubiquitin-Conjugating Enzyme UBE2D2 Is Responsible for FBXW2 (F-Box and WD Repeat Domain Containing 2)-Mediated Human GCM1 (Glial Cell Missing Homolog 1) Ubiquitination and Degradation." Biol Reprod 79(5):914-920.

18703417 | Recombinant CDC34

Liu, J., et al. (2008) "A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome." Am. J. Physiol. Heart.Circ. Physiol. 295(6): H2541-H2550.

18978187 | ubiquitin conjugation enzymes (F-340)

Todi, S. V., et al. (2007). "Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity." J. Biol. Chem.: 282(40): 29348-29358.

17693639 | rabbit 26 S fractions

Zhu, F., et al. (2006). "COOH-Terminal Src Kinase-Mediated c-Jun Phosphorylation Promotes c-Jun Degradation and Inhibits Cell Transformation." Cancer Res. 66(11): 5729-5736.

16740711 | Fraction II HeLa Conjugation Kit

Doss-Pepe E. W., et al. (2005) "[alpha]-Synuclein and Parkin Contribute to the Assembly of Ubiquitin Lysine 63-linked Multiubiquitin Chains." J. Biol. Chem. 280(17): 16619-16624.

15718234 | Fraction II

Kaneko-Oshikawa C., et al. (2005) "Mammalian E4 Is Required for Cardiac Development and Maintenance of the Nervous System." Mol. Cell. Biol. 25(24): 10953-10964.

16314518 | S100 lysate protein

Marteijn J. A. F., et al. (2005) "The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells." Blood 106(13): 4114-4123.

16118314 | http://bloodjournal.hematologylibrary.org/content/106/13/4114.long

Song B.-L. and DeBose-Boyd R.A. (2004) "Ubiquitination of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Permeabilized Cells Mediated by Cytosolic E1 and a Putative Membrane-bound Ubiquitin Ligase." J. Biol. Chem. 279(27): 28798-28806.

15090540 | Fraction I, Fraction II, S100 isolated from HeLa cells

Sampathu, D.M., et al. (2003) "Ubiquitination of [alpha]-synuclein is not required for formation of pathological inclusions in [alpha]--Synucleinopathies." Am. J. Path. 163: 91-100.

12819014 | ubiquitin conjugation fractions A and B (derived from mammalian cell lysate)

Shim, M., et al. (2003). "Lithium stabilizes the CCAAT/Enhancer-binding protein [alpha] (C/EBP[alpha]) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibitor of proteasomal activity." Genes Cells 11(7): 731-744.

12668682 | HeLa S-100 fraction

Ohh, M., et al. (2002). "An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.” EMBO Reports 3(2): 177-182.

11818338 | HeLa FII