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Join Our Team!
Boston Biochem is a fast-paced, rapidly growing and privately owned company with extensive expertise in the disciplines of protein biochemistry. Boston Biochem manufactures a full range of specialized reagents for the study of the ubiquitin-proteasome and related pathways. We also offer comprehensive custom services in the areas of fermentation, protein purification, protein expression, protein modification and characterization. Both divisions of the business facilitate the drug discovery efforts of the international biomedical research community. Boston Biochem is an equal opportunity employer.
We are currently recruiting for the following positions:
Scientist II
We seek a highly motivated and experienced protein biochemist to work independently and contribute to all aspects of ongoing research and development for individual products in the form of proteins or active enzymes, from beginning to end. Candidate should be familiar with optimizing source - whether expression system or native, to purification methods development, to extensive characterization and testing of final product.
The candidate must have strong expertise in protein expression and production, FPLC and HPLC protein purification, method development and optimization, protein quantitation, modification and enzyme analysis. Experience with fluorescent or FRET-baed assays is a plus. This individual is expected to initiate, plan and execute critical scientific research and development projects independently. Exceptional written and verbal communication skills will be required for documentation of data and internal report writing, drafting of SOP's, slide and poster preparation, and external representation of the company at conferences or with commercial partners. Strong organization, ability to multitask, and project management skills are essential to work within our interactive and dynamic team environment. Additionally, the cadidate should have highly proficient problem solving and analytical skills and be able to use technical discretion in the design, execution and interpretation of experiments that contribute to project goals.
Requires a Ph.D in the life sciences or biochemistry with a focus on cell signaling as an area of specialty, with 2-5 years post-graduate experience in academia and/or industry.
Scientist I
We seek an experienced protein biochemist to work independently and contribute to all aspects of ongoing research and development for individual products in the form of proteins or active enzymes, from beginning to end. Candidate should be familiar with optimizing source - whether expression system or native, to purification methods development, to extensive characterization and teting of final product.
Hands-on experience and extensive scientific knowledge in protein purification theory and practice is expected. Excellent written and verbal communication skills are essential for detailed report writing. The candidate is expected to be highly motivated and work well within an interactive and dynamic team environment. Additionally, the candidate should have highly proficient problem solving, organizational, and analytical skills, as well as be able to use technical discretion in the design, execution and interpretation of experiments that contribute to project goals. Candidate may be expected to provide guidance and supervision to less senior personnel and may assume a leading role for individual projects.
Requires a Ph.D and 0-2 years post-graduate experience in academia and/or industry, or MS with 5-10 years industry experience. Experience in the field of ubiquitin and/or general cell signaling is a plus.
Research Assistant
Major responsibilities include assisting in the lab with various tasks including basic lab maintenance and organization, preparing media and stock solutions. The candidate will also be trained to perform basic SOP procedures such as recombinant protein expression in E.coli and general protein analysis (solubility analysis, SDS‐PAGE, Western blotting, spectophotometry, quantitation). This is an opportunity to work in a fast paced exciting environment while learning many different aspects of protein biochemistry.
Successful candidates will have a familiarity with general biochemistry techniques, excellent attention to detail, and a desire and motivation to learn. Candidate must be highly organized, able to multitask, work independently and have good interpersonal skills. Must be able to work in a fast‐paced environment. Excellent communication, organization and collaborative skills are vital.
Candidate must have a BA/BS with 0‐2 years relevant lab experience. Recent graduates are encouraged to apply.
Senior Research Associate, Biochemistry/Protein Purification
Responsibilities will include the expression and purification of target proteins from recombinant systems (bacterial,yeast, insect cells) as well as natural sources. The candidate should have familiarity with general protein production and optimization (small and large-scale fermentation) and expression analysis. Hands-on experience and scientific knowledge in protein purification techniques including (extract preparation, inclusion body preparation, clarification, filtration, buffer exchange) and column chromatography (AKTA FPLC operation, ion exchange, gel filtration, affinity, etc.) is essential. Additional skills required for protein analysis include SDS-PAGE, Western blotting, spectrophotometry, quantitation, modification and enzyme assays. Work will be carefully documented in detailed reports.
Candidate must have a BA/BS or MS in life sciences with 2-5 years relevant industrial experience. Must be able to work in a fast-paced environment with minimal supervision. Excellent communication, organization and collaborative skills are vital.
Application Information
Boston Biochem offers an exciting flexible work environment with competitive compensation, benefits, and equity participation. Please email your resume and a cover letter describing your experience to careers@bostonbiochem.com or send it to:
Boston Biochem, Inc.
ATTN: Human Resources
840 Memorial Drive
Cambridge, MA 02139
Fax: (617) 492-3565






