Protein Production/Expression
Protein Purification
Protein Characterization/Modification/Assay Development
Custom Reagent Production
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Purified protein is indispensable for research and drug discovery programs.  Boston Biochem has extensive experience and expertise in protein purification from multiple sources including bacteria, yeast, insect, plant, mammalian cells or tissue sources.  The starting material can be generated in-house or provided by the client.  We perform purification from research to high-throughput screening scale quantities.  Our services are customized to identify efficient and cost-saving methods that accelerate your research.

• Protein denaturation and refolding
• Affinity purification: IMAC, GST, FLAG, Myc, HA, heparin, phosphocellulose, antibody matrices, custom matrices
• Classic chromatography: ion exchange, hydrophobic interaction, size exclusion, dye-ligand, regular and reverse-phase HPLC
  

• Development of de-novo methods for both native source and recombinant proteins
• Improvement of existing protocols with alternative strategies and chemistries
• Resin binding screening to optimize conditions for protein purification
• Refolding screening
• Production scale-up

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